HSPA4L

Last updated
HSPA4L
Identifiers
Aliases HSPA4L , APG-1, HSPH3, Osp94, heat shock protein family A (Hsp70) member 4 like
External IDs MGI: 107422 HomoloGene: 22610 GeneCards: HSPA4L
Gene location (Human)
Ideogram human chromosome 4.svg
Chr. Chromosome 4 (human) [1]
Human chromosome 4 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 4q28.1Start127,781,821 bp [1]
End127,840,733 bp [1]
RNA expression pattern
PBB GE HSPA4L 205543 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

22824

18415

Ensembl

ENSG00000164070

ENSMUSG00000025757

UniProt

O95757

P48722

RefSeq (mRNA)

NM_014278
NM_001317381
NM_001317382
NM_001317383

NM_011020

RefSeq (protein)

NP_001304310
NP_001304311
NP_001304312
NP_055093

NP_035150

Location (UCSC) Chr 4: 127.78 – 127.84 Mb Chr 3: 40.74 – 40.8 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heat shock 70 kDa protein 4L is a protein that in humans is encoded by the HSPA4L gene. [5] [6]

Contents

Related Research Articles

HSPA8

Heat shock 70 kDa protein 8 also known as heat shock cognate 71 kDa protein or Hsc70 or Hsp73 is a heat shock protein that in humans is encoded by the HSPA8 gene on chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Its functions contribute to biological processes including signal transduction, apoptosis, autophagy, protein homeostasis, and cell growth and differentiation. It has been associated with an extensive number of cancers, neurodegenerative diseases, cell senescence, and aging.

Heat shock protein 47

Heat shock protein 47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen.

HSPA1A

Heat shock 70 kDa protein 1, also termed Hsp72, is a protein that in humans is encoded by the HSPA1A gene. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. In addition, Hsp72 also facilitates DNA repair. Its functions contribute to biological processes including signal transduction, apoptosis, protein homeostasis, and cell growth and differentiation. It has been associated with an extensive number of cancers, neurodegenerative diseases, cell senescence and aging, and inflammatory diseases such as Diabetes mellitus type 2 and rheumatoid arthritis.

Heat shock 70kDa protein 1B, also known as HSPA1B, is a human gene. This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family.

HSF1

Heat shock factor 1 (HSF1) is a protein that in humans is encoded by the HSF1 gene. HSF1 is highly conserved in eukaryotes and is the primary mediator of transcriptional responses to proteotoxic stress with important roles in non-stress regulation such as development and metabolism.

HSP90AB1

Heat shock protein HSP 90-beta also called HSP90beta is a protein that in humans is encoded by the HSP90AB1 gene.

HSPB8

Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene.

Binding immunoglobulin protein

Binding immunoglobulin protein (BiP) also known as (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) or (Byun1) is a protein that in humans is encoded by the HSPA5 gene.

HSPA4

Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene.

HSPA9

Mitochondrial 70kDa heat shock protein (mtHsp70), also known as mortalin, is a protein that in humans is encoded by the HSPA9 gene.

STUB1

STUB1 is a human gene that codes for the protein CHIP.

DNAJB1

DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene.

HSPA1L

Heat shock 70 kDa protein 1L is a protein that in humans is encoded by the HSPA1L gene on chromosome 6. As a member of the heat shock protein 70 (Hsp70) family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded proteins, as well as stabilize or degrade mutant proteins. Its functions contribute to biological processes including signal transduction, apoptosis, protein homeostasis, and cell growth and differentiation. It has been associated with an extensive number of cancers, neurodegenerative diseases, cell senescence and aging, and Graft-versus-host disease.

HSPA2

Heat shock-related 70 kDa protein 2 is a protein that in humans is encoded by the HSPA2 gene.

HSF2

Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.

CCAAT/enhancer binding protein zeta

CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the CEBPZ gene.

HSPA14

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.

HSPA6

Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene.

PTPN21

Tyrosine-protein phosphatase non-receptor type 21 is an enzyme that in humans is encoded by the PTPN21 gene.

Heat shock protein family a (hsp70) member 12b

Heat shock protein family A (Hsp70) member 12B is a protein that in humans is encoded by the HSPA12B gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164070 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025757 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Nonoguchi K, Itoh K, Xue JH, Tokuchi H, Nishiyama H, Kaneko Y, Tatsumi K, Okuno H, Tomiwa K, Fujita J (Nov 1999). "Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes". Gene. 237 (1): 21–8. doi:10.1016/S0378-1119(99)00325-X. PMID   10524232.
  6. ↑ "Entrez Gene: HSPA4L heat shock 70kDa protein 4-like".

Further reading


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