HSPA4L

HSPA4L
Identifiers
Aliases	HSPA4L , APG-1, HSPH3, Osp94, heat shock protein family A (Hsp70) member 4 like, APG1
External IDs	MGI: 107422; HomoloGene: 22610; GeneCards: HSPA4L; OMA:HSPA4L - orthologs
Gene location (Human) Chr. Chromosome 4 (human) [1] Band 4q28.1 Start 127,781,821 bp [1] End 127,840,733 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 B Start 40,699,814 bp [2] End 40,750,538 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis Brodmann area 23 secondary oocyte postcentral gyrus pons gonad pars compacta bronchial epithelial cell Top expressed in spermatid spermatocyte neural layer of retina primary visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus zygote ventricular zone esophagus right kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding ATP binding Cellular component cytoplasm cytosol nucleus Biological process response to unfolded protein protein folding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22824 18415 Ensembl ENSG00000164070 ENSMUSG00000025757 UniProt O95757 P48722 RefSeq (mRNA) NM_014278 NM_001317381 NM_001317382 NM_001317383 NM_011020 RefSeq (protein) NP_001304310 NP_001304311 NP_001304312 NP_055093 NP_035150 Location (UCSC) Chr 4: 127.78 – 127.84 Mb Chr 3: 40.7 – 40.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heat shock 70 kDa protein 4L is a protein that in humans is encoded by the HSPA4L gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000164070 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025757 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nonoguchi K, Itoh K, Xue JH, Tokuchi H, Nishiyama H, Kaneko Y, Tatsumi K, Okuno H, Tomiwa K, Fujita J (Nov 1999). "Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes". Gene. 237 (1): 21–8. doi:10.1016/S0378-1119(99)00325-X. PMID   10524232.
6. "Entrez Gene: HSPA4L heat shock 70kDa protein 4-like".

Further reading

• Nonoguchi K, Tokuchi H, Okuno H, Watanabe H, Egawa H, Saito K, Ogawa O, Fujita J (2001). "Expression of Apg-1, a member of the Hsp110 family, in the human testis and sperm". Int. J. Urol. 8 (6): 308–14. doi: 10.1046/j.1442-2042.2001.00304.x . PMID   11389747. S2CID   27280317.
• Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K, Hama T, Suzuki A, Hamada F, Otaka M, Shoji Y, Takada G (2003). "Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization". Eur. J. Biochem. 269 (22): 5632–41. doi: 10.1046/j.1432-1033.2002.03272.x . PMID   12423363.
• Colgan SP, Pitman RS, Nagaishi T, Mizoguchi A, Mizoguchi E, Mayer LF, Shao L, Sartor RB, Subjeck JR, Blumberg RS (2003). "Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells". J. Clin. Invest. 112 (5): 745–54. doi:10.1172/JCI17241. PMC   182184 . PMID   12952923.
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.

External links

• HSPA4L+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)