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Christian Friedrich Samuel Hahnemann was a German physician, best known for creating the pseudoscientific system of alternative medicine called homeopathy.
Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S. subsidiary of the German company Schering AG, which was founded in 1851 by Ernst Christian Friedrich Schering. As a result of nationalization, it became an independent company. In 1971, the Schering Corporation merged with Plough to form Schering-Plough. On November 4, 2009 Merck & Co. merged with Schering-Plough with the new company taking the name of Merck & Co.
The Organon is the standard collection of Aristotle's six works on logical analysis and dialectic. The name Organon was given by Aristotle's followers, the Peripatetics.
The Creature from the Pit is the third serial of the 17th season of the British science fiction television series Doctor Who, which was first broadcast in four weekly parts on BBC1 from 27 October to 17 November 1979. It was the first serial to feature David Brierley as the voice of K9.
Slough Feg is an American heavy metal band from Pennsylvania, formed in 1990 and currently based in the San Francisco Bay Area. Taking their name from the Celtic folklore-influenced comic book Sláine, the band released their self-titled debut album in 1996. Slough Feg combines influences from traditional heavy metal bands such as Iron Maiden, Brocas Helm, and Thin Lizzy, as well as English folk metal band Skyclad.
Rapacuronium bromide is a rapidly acting, non-depolarizing aminosteroid neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care. As a non-depolarizing agent it did not cause initial stimulation of muscles before weakening them.
Organon of the Art of Healing by Samuel Hahnemann, 1810, laid out the doctrine of his ideas of homoeopathy. The work was repeatedly revised by Hahnemann and published in six editions, with the name changed from the second onwards to Organon of Medicine, and has been so since the mid-19th century.
Organon & Co. is an American pharmaceutical company headquartered in Jersey City, New Jersey. Organon specializes in the following core therapeutic fields: reproductive medicine, contraception, psychiatry, hormone replacement therapy (HRT), and anesthesia. Organon sells to international markets.
New Organon is the tenth studio album by American heavy metal band Slough Feg. It was released under their original name "The Lord Weird Slough Feg" on June 14, 2019, by Cruz del Sur Music, their return to that label after being signed to Metal Blade Records for their previous album Digital Resistance.
Farampator is an ampakine drug. It was developed by Cortex Pharmaceuticals, and licensed to Organon BioSciences for commercial development. Following the purchase of Organon by Schering-Plough in 2007, the development license to farampator was transferred. The development of farampator was eventually terminated, reportedly due to concerns about cardiac toxicity.
Apronal, or apronalide, also known as allylisopropylacetylurea or allylisopropylacetylcarbamide, is a hypnotic/sedative drug of the ureide (acylurea) group synthesized in 1926 by Hoffmann-La Roche that is no longer used except in Japan. Though it is not a barbiturate, apronalide is similar in structure to the barbiturates. In accordance, it is similar in action to the barbiturates, although considerably milder in comparison. Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use.
The Newhouse Research Site is a drug research facility situated 15 miles (24 km) east of Glasgow in central Scotland. It is located beside the M8 motorway in Newhouse, North Lanarkshire. The site is an early drug discovery research centre with a track record of generating a succession of products in the areas of anaesthesia and psychiatry. In 2007, the Royal Society of Chemistry Malcolm Campbell Memorial Prize was awarded to researchers for its work on a new anaesthesia drug, sugammadex. It currently employs 250 scientists across a range of disciplines including medicinal chemistry, molecular biology and drug metabolism. The site is currently the largest private drug discovery centre in Scotland, and one of the biggest in the UK.
ORG-12962 is a pyridinylpiperazine drug developed by Organon, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity at 5-HT2C and lowest at 5-HT2B subtypes. It was developed as a potential anti-anxiety drug, but was discontinued from human trials after tests in a public speaking challenge showed that its anti-anxiety effects were accompanied by side effects such as dizziness and a "spacey" feeling, which were attributed to poor selectivity in vivo over the hallucinogenic 5-HT2A receptor.
ORG-25435 is a synthetic drug developed by Organon International, which acts as a GABAA receptor positive allosteric modulator, and produces sedative effects. It has been researched for use as an intravenous anesthetic agent, with positive results in initial trials, although negative side effects like hypotension and tachycardia, as well as unpredictable pharmacokinetics at higher doses, have meant it has ultimately not been adopted for medical use.
Chaos on Deponia is a graphic adventure video game developed and published by Daedalic Entertainment. A sequel to Deponia, it continues the story of the main character Rufus as he attempts to escape from his home planet Deponia.
PTI-2 (SGT-49) is an indole-based synthetic cannabinoid. It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-1. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.
PTI-1 (SGT-48) is an indole-based synthetic cannabinoid. It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-2. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.
Tigestol, also known as 17α-ethynylestr-5(10)-en-17β-ol, is a steroidal progestin of the 19-nortestosterone group that was developed by Organon in the 1960s but was never marketed. It is an isomer of the related 19-nortestosterone derivative progestins lynestrenol and cingestol.
Ethinylestradiol/etonogestrel, sold under the brand names NuvaRing among others, is a hormonal vaginal ring used for birth control and to improve menstrual symptoms. It contains ethinylestradiol, an estrogen, and etonogestrel, a progestin. It is used by insertion into the vagina. Pregnancy occurs in about 0.3% of women with perfect use and 9% of women with typical use.
ORG-201745 is a progestin which was originated by Organon and was under development by Schering-Plough for the treatment of "female genital diseases" and as a hormonal contraceptive for the prevention of pregnancy but was never marketed.
References
- ↑ "Research programme: progestogen-based therapeutics - Organon - AdisInsight". adisinsight.springer.com.
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