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Formula | C22H29N3O |
Molar mass | 351.494 g·mol−1 |
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Etodesnitazene (also known as desnitroetonitazene, etazen, etazene, and etazone) is a benzimidazole-derived opioid analgesic drug, which was originally developed in the late 1950s alongside etonitazene and a range of related derivatives. [1] It is many times less potent than etonitazene itself, but still 70 times more potent than morphine in animal studies. Corresponding analogues where the N,N-diethyl group is replaced by piperidine or pyrrolidine rings also retain significant activity (10 times and 20 times morphine, respectively). [2] Etodesnitazene has been sold as a designer drug, [3] first being identified in both Poland and Finland in March 2020. [4] [5]
Since 15 January 2025 it is covered by the UK's generic definition on 2-benzyl benzimidazole derived opioids [6] [7] because it contains the 2-(2-benzyl-benzimidazol-1-yl)ethanamine backbone with only the following modification: [8]