P-7521

Last updated

P-7521
P-7521 structure.png
Identifiers
  • 3-[9-methoxy-3-(2-phenylethyl)-3-azabicyclo[3.3.1]nonan-9-yl]phenol
CAS Number
PubChem CID
Chemical and physical data
Formula C23H29NO2
Molar mass 351.490 g·mol−1
3D model (JSmol)
  • COC1(C2CCCC1CN(C2)CCC3=CC=CC=C3)C4=CC(=CC=C4)O
  • InChI=1S/C23H29NO2/c1-26-23(19-9-6-12-22(25)15-19)20-10-5-11-21(23)17-24(16-20)14-13-18-7-3-2-4-8-18/h2-4,6-9,12,15,20-21,25H,5,10-11,13-14,16-17H2,1H3
  • Key:UXFOUDJIDGKJDT-UHFFFAOYSA-N

P-7521 is an opioid analgesic drug developed in China in the 1980s. [1] [2] [3] [4]

See also

References

  1. ↑ Zhou J, Zheng WJ, Chi ZQ (January 1987). "[Analgesic activity and respiratory inhibition of 3-beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicyclo [3,3,1]-nonane (P-7521) in rabbits]". Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 8 (1): 10–13. PMID   2955652.
  2. ↑ Zhou DH, Ge BL, Xu XJ, Chi ZQ (November 1988). "[Effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (P-7521) on opiate receptor binding in vitro]". Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 9 (6): 511–515. PMID   2855686.
  3. ↑ Jin WQ, Fan LQ, Chen XJ, Chi ZQ (May 1989). "P-7521--a new irreversible opioid ligand". Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica. 10 (3): 205–210. PMID   2558497.
  4. ↑ Chi ZQ, Jin WQ (1990). "A potent and long-lasting ligand, azabicyclononane (P-7521)". Progress in Clinical and Biological Research. 328: 1–4. PMID   2154758.
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