Parafluorofuranylfentanyl

Last updated
Parafluorofuranylfentanyl
Parafluorofuranylfentanyl structure.png
Legal status
Legal status
Identifiers
  • N-(4-fluorophenyl)-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C24H25FN2O2
Molar mass 392.474 g·mol−1
3D model (JSmol)
  • C1CN(CCC1N(C2=CC=C(C=C2)F)C(=O)C3=CC=CO3)CCC4=CC=CC=C4
  • InChI=1S/C24H25FN2O2/c25-20-8-10-21(11-9-20)27(24(28)23-7-4-18-29-23)22-13-16-26(17-14-22)15-12-19-5-2-1-3-6-19/h1-11,18,22H,12-17H2
  • Key:MGEQOAJOFFXWTR-UHFFFAOYSA-N

para-Fluorofuranylfentanyl (FFF, p-F-Fu-F) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. [2] As with other fentanyl analogues, parafluorofuranylfentanyl has significant side effects including itching, nausea and potentially serious respiratory depression, which can be life-threatening, and it has been linked to numerous deaths from overdose. [3] It falls within the definition of Schedule I drugs in the USA under federal drug analogue legislation, and is specifically listed as a Schedule I drug in North Dakota. [4]

See also

References

  1. ↑ Drug Enforcement Administration, Department of Justice (2018). "Schedules of Controlled Substances:Temporary Placement of Fentanyl-Related Substances in Schedule I. Temporary amendment; temporary scheduling order". Federal Register. 83 (25): 5188–92. PMID   29932611.
  2. ↑ Vincenti F, Montesano C, Di Ottavio F, Gregori A, Compagnone D, Sergi M, Dorrestein P (2020). "Molecular Networking: A Useful Tool for the Identification of New Psychoactive Substances in Seizures by LC-HRMS". Frontiers in Chemistry. 8 572952. Bibcode:2020FrCh....8.1039V. doi: 10.3389/fchem.2020.572952 . PMC   7723841 . PMID   33324608.
  3. ↑ Rodriguez Salas J, Krotulski AJ, Newman R, Thogmartin JR, Mohr AL, Logan BK (April 2022). "Concentrations of para-Fluorofuranylfentanyl in Paired Central and Peripheral Blood Collected during Postmortem Death Investigations". Journal of Analytical Toxicology. 46 (4): 358–373. doi:10.1093/jat/bkab025. PMID   33693685.
  4. ↑ "AN ACT to amend and reenact sections 19-03.1-05, 19-03.1-11, and 19-03.1-13 of the North Dakota Century Code, relating to the scheduling of controlled substances; and to declare an emergency" (PDF). Sixty-eighth Legislative Assembly of North Dakota in Regular Session. 3 January 2023.
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