Avihepadnavirus

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Avihepadnavirus
Virus classification OOjs UI icon edit-ltr.svg
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Blubervirales
Family: Hepadnaviridae
Genus:Avihepadnavirus

Avihepadnavirus is a genus of viruses, in the family Hepadnaviridae . [1] Birds serve as natural hosts. There are five species in this genus. [1] Diseases associated with this genus include: hepatitis, hepatocellular carcinomas (chronic infections), and cirrhosis. [2] [3]

Contents

Taxonomy

The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species: [4]

Structure

Viruses in the genus Avihepadnavirus are enveloped, with spherical geometries, and T=4 symmetry. The diameter is around 42 nm. Genomes are circular, around 3.2kb in length. The genome codes for 7 proteins. [1] [2]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
AvihepadnavirusIcosahedralT=4Non-envelopedCircularMonopartite

Life cycle

Viral replication is nucleo-cytoplasmic. Replication follows the dsDNA(RT) replication model. DNA-templated transcription, specifically dsDNA-RT transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by ribosomal shunting. The virus exits the host cell by budding, and nuclear pore export. Birds serve as the natural host. Transmission routes are parental, sexual, and blood. [1] [2]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
AvihepadnavirusBirdsHepatocytesCell receptor endocytosisBuddingNucleusCytoplasmVertical: parental; sex; blood

References

  1. 1 2 3 4 "ICTV Report Hepadnaviridae".
  2. 1 2 3 "Viral Zone". ExPASy. Retrieved 12 June 2015.
  3. Guo, Haitao; Mason, William (2005). "Identification and Characterization of Avihepadnaviruses Isolated from Exotic Anseriformes Maintained in Captivity". Journal of Virology. 79 (5). American Society for Microbiology: 2729–2742. doi:10.1128/JVI.79.5.2729-2742.2005. PMC   548436 . PMID   15708992.
  4. "Virus Taxonomy: 2024 Release". International Committee on Taxonomy of Viruses. Retrieved 22 March 2025.