Dipyanone

Last updated

Dipyanone
Dipyanone.svg
Identifiers
  • 4,4-diphenyl-6-(1-pyrrolidinyl)-heptan-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C23H29NO
Molar mass 335.491 g·mol−1
3D model (JSmol)
  • CCC(=O)C(CC(C)N1CCCC1)(c1ccccc1)c1ccccc1
  • InChI=1S/C23H29NO/c1-3-22(25)23(20-12-6-4-7-13-20,21-14-8-5-9-15-21)18-19(2)24-16-10-11-17-24/h4-9,12-15,19H,3,10-11,16-18H2,1-2H3
  • Key:LJIUPFDRFKFNJE-UHFFFAOYSA-N

Dipyanone is an opioid analgesic which has been sold as a designer drug, first identified in Germany in 2021. [1] [2] It is closely related to medically used drugs such as methadone, dipipanone and phenadoxone, but is slightly less potent. [3] [4] [5]

See also

References

  1. ↑ European Monitoring Centre for Drugs and Drug Addiction. (June 2022). New psychoactive substances: 25 years of early warning and response in Europe. An update from the EU Early Warning System (PDF). European Monitoring Centre for Drugs and Drug Addiction. doi:10.2810/882318 (inactive 12 July 2025). ISBN   978-92-9497-737-3.{{cite book}}: CS1 maint: DOI inactive as of July 2025 (link)
  2. ↑ Vandeputte MM, Walton SE, Shuda SA, Papsun DM, Krotulski AJ, Stove CP (September 2023). "Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs". Analytical and Bioanalytical Chemistry. 415 (21): 5165–5180. doi:10.1007/s00216-023-04722-7. PMID   37173408.
  3. ↑ Ofner P, Walton E (1950). "444. Search for new analgesics. Part IV. Variations in the basic side-chain of amidone". Journal of the Chemical Society (Resumed): 2158. doi:10.1039/JR9500002158.
  4. ↑ Lenz GR, Evans SM, Walters DE, Hopfinger AJ (1986). Opiates. Academic Press. pp. 406–407. ISBN   978-0-12-443830-9.
  5. ↑ Berardinelli D, Kutzler J, Taoussi O, Zaami S, Pichini S, Basile G, et al. (June 2025). "Dipyanone, a new methadone-like synthetic opioid: In vitro and in vivo human metabolism and pharmacological profiling". Archives of Toxicology. 99 (6): 2339–2353. Bibcode:2025ArTox..99.2339B. doi:10.1007/s00204-025-04023-1. PMC   12185669 . PMID   40295323.
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