RAM-378

Last updated
RAM-378
RAM-378.svg
Identifiers
  • 3,6,14-trihydroxy-4,5α-epoxy-17-(2-phenylethyl)morphinan
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C24H27NO4
Molar mass 393.483 g·mol−1
3D model (JSmol)
  • C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CCC6=CC=CC=C6)[C@H]([C@H]1O)OC5=C(C=C4)O)O
  • InChI=1S/C24H27NO4/c26-17-7-6-16-14-19-24(28)10-8-18(27)22-23(24,20(16)21(17)29-22)11-13-25(19)12-9-15-4-2-1-3-5-15/h1-7,18-19,22,26-28H,8-14H2/t18-,19+,22-,23-,24+/m0/s1
  • Key:GAHRZWMAHDWVCL-VKJMTUIMSA-N
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RAM-378 [1] (7,8-Dihydro-14-hydroxy-N-phenethylnormorphine) is an opioid analgesic. It is the N-phenethyl derivative of hydromorphinol.

See also

References

  1. ↑ Ben Haddou T, Béni S, Hosztafi S, Malfacini D, Calo G, Schmidhammer H, Spetea M (2014). "Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity". PLOS ONE. 9 (6) e99231. Bibcode:2014PLoSO...999231B. doi: 10.1371/journal.pone.0099231 . PMC   4053365 . PMID   24919067.


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