| Suipoxvirus | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Varidnaviria |
| Kingdom: | Bamfordvirae |
| Phylum: | Nucleocytoviricota |
| Class: | Pokkesviricetes |
| Order: | Chitovirales |
| Family: | Poxviridae |
| Subfamily: | Chordopoxvirinae |
| Genus: | Suipoxvirus |
Suipoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae . Swine serve as natural hosts. There is only one species in this genus: Swinepox virus. Diseases associated with this genus include asymptomatic skin disease. [1] [2]
Viruses in Suipoxvirus are enveloped, with brick-shaped geometries. Genomes are linear, around 175 kilobases in length. [1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Suipoxvirus | Brick-shaped | Enveloped | Linear | Monopartite |
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the viral proteins to host glycosaminoglycans (GAGs), which mediates endocytosis of the virus into the host cell. The virion undergoes fusion with the plasma membrane to release the core into the host cytoplasm. Early genes are transcribed in the cytoplasm by viral RNA polymerase. Early expression begins at 30 minutes post-infection. The core is completely uncoated as early expression ends, and the viral genome is now free in the cytoplasm.[ citation needed ]
Intermediate genes are expressed, triggering genomic DNA replication at approximately 100 minutes post-infection. Late genes are expressed from 140 min to 48 hours post-infection, producing all structural proteins. The assembly of progeny virions starts in cytoplasmic viral factories and produces a spherical, immature particle. This virus particle matures into a brick-shaped, intracellular mature virion (IMV). This IMV virion can be released upon cell lysis, or can acquire a second double membrane from trans-Golgi and bud as external enveloped virion (EEV).[ citation needed ]
Replication follows the DNA strand displacement model. DNA-templated transcription is the method of transcription. The virus exits the host cell by existing in occlusion bodies after cell death and remaining infectious until finding another host. Swine serve as the natural host. [1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Suipoxvirus | Swine | None | Glycosaminoglycans | Lysis; budding | Cytoplasm | Cytoplasm | Unknown |
Swinepox is a worldwide disease of the pig, caused by a virus of the family Poxviridae and the genus Suipoxvirus. It is the most common cause of pox disease in pigs, with vaccinia virus being the next most common cause of outbreaks. [3] It is a mild to severe disease depending on the louse it was contracted from. Symptoms include papules and pustules on the skin of the abdomen. Characteristic lesions on the lower abdomen have dark hemorrhagic centers. [4] Swinepox is transmitted by direct contact and by the pig louse, Hematopinus suis . Often the hooves go crusty due to the animals water content in its body being used for fighting the infection. This in serious Swine pox cases can cause malformed hoofs and damage the ability for the pig to walk properly. In some extremely rare cases, the genetics of the animal can be changed by this disease but go unnoticed in terms of physical symptoms; this, if contracted by breeding pigs is very threatening for the potential baby piglets to be born. Piglets born from parents that both have the severest strain of the disease will be born frequently with disfigurements such as a tail that is bulbous, and crooked snouts. The inside of the animal is also affected by the genetic strain by making the muscles and fat of the animal pus filled and also weakens the piglets organs over time resulting in death.[ citation needed ]
Poxviridae is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox.
Parapoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Chordopoxvirinae. Like all members of the family Poxviridae, they are oval, relatively large, double-stranded DNA viruses. Parapoxviruses have a unique spiral coat that distinguishes them from other poxviruses. Parapoxviruses infect vertebrates, including a wide selection of mammals, and humans.
Orthopoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. Vertebrates, including mammals and humans, and arthropods serve as natural hosts. There are 12 species in this genus. Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and monkeypox. The most widely known member of the genus is Variola virus, which causes smallpox. It was eradicated globally by 1977, through the use of Vaccinia virus as a vaccine. The most recently described species is the Alaskapox virus, first isolated in 2015.
Molluscum contagiosum virus (MCV) is a species of DNA poxvirus that causes the human skin infection molluscum contagiosum. Molluscum contagiosum affects about 200,000 people a year, about 1% of all diagnosed skin diseases. Diagnosis is based on the size and shape of the skin lesions and can be confirmed with a biopsy, as the virus cannot be routinely cultured. Molluscum contagiosum virus is the only species in the genus Molluscipoxvirus. MCV is a member of the subfamily Chordopoxvirinae of family Poxviridae. Other commonly known viruses that reside in the subfamily Chordopoxvirinae are variola virus and monkeypox virus.
Sheeppox is a highly contagious disease of sheep caused by a poxvirus different from the benign orf. This virus is in the family Poxviridae and genus Capripoxvirus. Sheeppox virus (SPV) is the most severe of all the animal pox diseases and can result in some of the most significant economic consequences due to poor wool and leather quality.
Avipoxvirus is a genus of viruses within the family Poxviridae. Poxviridae is the family of viruses which cause the afflicted organism to have poxes as a symptom. Poxviruses have generally large genomes, and other such examples include smallpox and monkeypox. Members of the genus Avipoxvirus infect specifically birds. Avipoxviruses are unable to complete their replication cycle in non-avian species. Although it is comparably slow-spreading, Avipoxvirus is known to cause symptoms like pustules full of pus lining the skin and diphtheria-like symptoms. These diphtheria-like symptoms might include diphtheric necrotic membranes lining the mouth and the upper respiratory tract. Like other avian viruses, it can be transmitted through vectors mechanically such as through mosquitoes. There is no evidence that this virus can infect humans.
Veterinary virology is the study of viruses in non-human animals. It is an important branch of veterinary medicine.
Turkeypox virus is a virus of the family Poxviridae and the genus Avipoxvirus that causes turkeypox. It is one of the most common diseases in the wild turkey population. Turkeypox, like all avipoxviruses, is transmitted either through skin contact or by arthropods acting as mechanical vectors.
Yatapoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Chordopoxvirinae. Monkeys and baboons serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: histiocytomas, tumor-like mass of mononuclear cells.
Chordopoxvirinae is a subfamily of viruses in the family Poxviridae. Humans, vertebrates, and arthropods serve as natural hosts. Currently, 52 species are placed in this subfamily, divided among 18 genera. Diseases associated with this subfamily include smallpox.
Entomopoxvirinae is a subfamily of viruses, in the family Poxviridae. Insects, human, vertebrates, and arthropods serve as natural hosts. There are currently 31 species in this subfamily, divided among 4 genera with one species unassigned to a genus. Diseases associated with this subfamily include: impairment of motility and development.
Capripoxvirus is a genus of viruses in the subfamily Chordopoxvirinae and the family Poxviridae. Capripoxviruses are among the most serious of all animal poxviruses. All CaPV are notifiable diseases to the OIE. Sheep, goat, and cattle serve as natural hosts. These viruses cause negative economic consequences by damaging hides and wool and forcing the establishment of trade restrictions in response to an outbreak. The genus consists of three species: sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV). They share no serological relationship with camel pox, horse pox, or avian poxes. Capripoxviruses for sheeppox and goatpox infect only sheep and goat respectively. However, it is probable that North American relatives, the mountain goat and mountain sheep, may be susceptible to the strains but has not been experimentally proven. Lumpy skin disease virus affects primarily cattle, but studies have been shown that giraffes and impala are also susceptible to LSDV. Humans cannot be infected by Capripoxviruses.
Alphaentomopoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Entomopoxvirinae. Coleoptera insects serve as natural hosts. There are seven species in this genus.
Betaentomopoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Entomopoxvirinae. Lepidoptera and orthoptera insects serve as natural hosts. There are 16 species in this genus.
Cervidpoxvirus is a genus of viruses in the family Poxviridae in the subfamily Chordopoxvirinae. Deer serve as natural hosts. Only one species is in this genus: Mule deerpox virus.
Gammaentomopoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Entomopoxvirinae. Lepidoptera and orthoptera insects serve as natural hosts. There are six species in this genus.
Leporipoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Chordopoxvirinae. Lagomorphs and squirrels serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: myxomatosis.
Crocodylidpoxvirus is a genus of viruses, in the family Poxviridae, in the subfamily Chordopoxvirinae. Crocodiles serve as natural hosts. There is only one species in this genus: Nile crocodilepox virus. Diseases associated with this genus include: nodular skin lesions in young animals. Symptoms vary from a nonfatal dermatitis to more severe disease characterized by ophthalmia, rhinitis resulting in asphyxia, and debilitating illness with stunting and high mortality.
Raccoonpox virus (RCN) is a double-stranded DNA virus and a member of the orthopoxviruses in the family Poxviridae and subfamily Chordopoxvirinae which consists of eight genera: Avipoxvirus, Capripoxvirus, Leporipoxvirus, Molluscipoxvirus, Orthopoxvirus, Parapoxvirus, Suipoxvirus and Yatapoxvirus Vertebrates are the natural host of Chordopoxvirinae subfamily viruses. More specifically, raccoons are the natural hosts of RCN. RCN was isolated in 1961 from the upper respiratory tissues of 2 raccoons in a group of 92 observably healthy raccoons trapped close to Aberdeen, Maryland.
Red deerpox virus (RDPV) is a species of virus in the genus Parapoxvirus. It has been reported in deer in New Zealand, and in wild ruminants in Italy.
