Acyl-CoA hydrolase

Last updated
acyl-CoA hydrolase
Identifiers
EC no. 3.1.2.20
CAS no. 37270-64-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

The enzyme acyl-CoA hydrolase (EC 3.1.2.20) catalyzes the reaction

acyl-CoA + H2O CoA + a carboxylate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is acyl-CoA hydrolase. Other names in common use include acyl coenzyme A thioesterase, acyl-CoA thioesterase, acyl coenzyme A hydrolase, thioesterase B, thioesterase II, and acyl-CoA thioesterase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1Y7U and 2GVH.

References