Interleukin-12 receptor

beta 2 subunit, interleukin 12 receptor, beta 2
beta 2 subunit, interleukin 12 receptor, beta 2
Identifiers
Symbol	IL12RB2
NCBI gene	3595
HGNC	5972
OMIM	601642
RefSeq	NM_001559
UniProt	Q99665
Other data
Locus	Chr. 1 p31.3-31.2
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Search for
Structures	Swiss-model
Domains	InterPro

interleukin 12 receptor, beta 1
interleukin 12 receptor, beta 1
Identifiers
Symbol	IL12RB1
Alt. symbols	IL12RB, CD212
NCBI gene	3594
HGNC	5971
OMIM	601604
RefSeq	NM_005535
UniProt	P42701
Other data
Locus	Chr. 19 p13.1
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Last updated May 28, 2025

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1 ^[1] and beta 2 subunits.^[2]

References

↑ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130" . J. Immunol. 153 (1): 128–36. doi:10.4049/jimmunol.153.1.128. PMID 7911493. S2CID 9211163.
↑ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. Bibcode:1996PNAS...9314002P. doi: 10.1073/pnas.93.24.14002 . PMC 19484 . PMID 8943050.

External links

Receptors,+Interleukin-12 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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[pmid7911493-1] Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130" . J. Immunol. 153 (1): 128–36. doi:10.4049/jimmunol.153.1.128. PMID 7911493. S2CID 9211163.

[pmid8943050-2] Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. Bibcode:1996PNAS...9314002P. doi: 10.1073/pnas.93.24.14002 . PMC 19484 . PMID 8943050.

[1]

[2]