Trimetozine

Last updated
Trimetozine
Trimetozine.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration 		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • Morpholin-4-yl-(3,4,5-trimethoxyphenyl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.010.215 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C14H19NO5
Molar mass 281.308 g·mol−1
3D model (JSmol)
  • COC1=CC(=CC(=C1OC)OC)C(=O)N2CCOCC2

Trimetozine (Opalene, Trimolide, Trioxazine) is a sedative that has been marketed in Europe since 1959. [1] [2] It also has mild tranquilizing effects and has been used in the treatment of anxiety. [3] [4] Its mechanism of action is unclear.[ citation needed ]

Conversion of the amide in trimetozine to the thioamide gives Tritiozine.

References

  1. ↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. p. 1932. ISBN   3-88763-075-0.
  2. ↑ David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN   0-412-46630-9.
  3. ↑ Taverna P, Ferrari G (June 1970). "[Clinical trial of a new tranquilizing agent: trioxazine]". Minerva Medica (in Italian). 61 (46): 2574–90. PMID   5425739.
  4. ↑ Shpak VM, Shcheglova AI (August 1968). "[Trioxazine in the treatment of night anxiety in children]". Pediatriia (in Russian). 47 (8): 76–7. PMID   5730033.
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