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The 1858 Philadelphia mayoral election saw the election of Alexander Henry, who unseated incumbent mayor Richard Vaux.
| Party | Candidate | Votes | % | |
|---|---|---|---|---|
| People's | Alexander Henry | 33,771 | 53.74 | |
| Democratic | Richard Vaux (incumbent) | 29,068 | 46.26 | |
| Total votes | 62,839 | 100.00 | ||