RPLP0

Last updated
RPLP0
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases RPLP0 , L10E, LP0, P0, PRLP0, RPP0, ribosomal protein lateral stalk subunit P0
External IDs OMIM: 180510 MGI: 1927636 HomoloGene: 6517 GeneCards: RPLP0
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_053275
NM_001002

NM_007475

RefSeq (protein)

NP_000993
NP_444505
NP_000993.1
NP_444505.1

NP_031501

Location (UCSC) Chr 12: 120.2 – 120.2 Mb Chr 5: 115.56 – 115.56 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

60S acidic ribosomal protein P0 is a protein that in humans is encoded by the RPLP0 gene. [5] [6]

Ribosomes catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [6]

Related Research Articles

60S acidic ribosomal protein P2

60S acidic ribosomal protein P2 is a protein that in humans is encoded by the RPLP2 gene.

60S ribosomal protein L6 Protein-coding gene in the species Homo sapiens

60S ribosomal protein L6 is a protein that in humans is encoded by the RPL6 gene.

40S ribosomal protein S13

40S ribosomal protein S13 is a protein that in humans is encoded by the RPS13 gene.

60S ribosomal protein L4

60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.

40S ribosomal protein S9

40S ribosomal protein S9 is a protein that in humans is encoded by the RPS9 gene.

60S ribosomal protein L28

60S ribosomal protein L28 is a protein that in humans is encoded by the RPL28 gene.

60S ribosomal protein L24

60S ribosomal protein L24 is a protein that in humans is encoded by the RPL24 gene.

60S ribosomal protein L13a

60S ribosomal protein L13a is a protein that in humans is encoded by the RPL13A gene.

60S ribosomal protein L8

60S ribosomal protein L8 is a protein that in humans is encoded by the RPL8 gene.

60S ribosomal protein L19

60S ribosomal protein L19 is a protein that in humans is encoded by the RPL19 gene.

40S ribosomal protein S20

40S ribosomal protein S20 is a protein that in humans is encoded by the RPS20 gene.

60S ribosomal protein L35

60S ribosomal protein L35 is a protein that in humans is encoded by the RPL35 gene.

60S ribosomal protein L18

60S ribosomal protein L18 is a protein that in humans is encoded by the RPL18 gene.

40S ribosomal protein S11

40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.

60S ribosomal protein L41

60S ribosomal protein L41 is a protein that in humans is encoded by the RPL41 gene.

60S ribosomal protein L17

60S ribosomal protein L17 is a protein that in humans is encoded by the RPL17 gene.

Mitochondrial ribosomal protein L41

39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.

60S ribosomal protein L37a

60S ribosomal protein L37a is a protein that in humans is encoded by the RPL37A gene.

60S ribosomal protein L39

60S ribosomal protein L39 is a protein that in humans is encoded by the RPL39 gene.

MRPL10

39S ribosomal protein L10, mitochondrial is a protein that in humans is encoded by the MRPL10 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000089157 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000067274 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi: 10.1101/gr.8.5.509 . PMID   9582194.
  6. 1 2 "Entrez Gene: RPLP0 ribosomal protein, large, P0".

Further reading