| EEF1D | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | EEF1D , EF-1D, EF1D, FP1047, eukaryotic translation elongation factor 1 delta | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 130592 MGI: 1913906 HomoloGene: 23404 GeneCards: EEF1D | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Elongation factor 1-delta is a protein that in humans is encoded by the EEF1D gene. [5]
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants have been found for this gene, however, the full length nature of only two variants has been determined. [6]
EEF1D has been shown to interact with Glycyl-tRNA synthetase, [7] EEF1G [8] [9] and KTN1, [10] and is predicted to interact with TMEM63A. [11]
EF-Tu is a prokaryotic elongation factor responsible for catalyzing the binding of an aminoacyl-tRNA (aa-tRNA) to the ribosome. It is a G-protein, and facilitates the selection and binding of an aa-tRNA to the A-site of the ribosome. As a reflection of its crucial role in translation, EF-Tu is one of the most abundant and highly conserved proteins in prokaryotes. It is found in eukaryotic mitochondria as TUFM.
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIα), a.k.a.Ca2+/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene.
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform is an enzyme that is encoded by the PPP2CA gene.
Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.
Glycine—tRNA ligase also known as glycyl–tRNA synthetase is an enzyme that in humans is encoded by the GARS1 gene.
Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is encoded by the EEF1A1 gene.
Tryptophanyl-tRNA synthetase, cytoplasmic is an aminoacyl-tRNA synthetase enzyme that attaches the amino acid tryptophan to its cognate tRNA. In humans, it is encoded by the WARS gene.
Elongation factor 1-beta is a protein that in humans is encoded by the EEF1B2 gene.
Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G.
Elongation factor 1-gamma is a protein that in humans is encoded by the EEF1G gene.
Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.
Arginyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the RARS gene.
Aspartyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the DARS gene.
Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene.
Glutaminyl-tRNA synthetase is an enzyme that in humans is encoded by the QARS gene.
Valyl-tRNA synthetase is an enzyme that in humans is encoded by the VARS gene.
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.
Elongation factor G 1, mitochondrial is a protein that in humans is encoded by the GFM1 gene. It is an EF-G homolog.
EF-G is a prokaryotic elongation factor involved in protein translation. As a GTPase, EF-G catalyzes the movement (translocation) of transfer RNA (tRNA) and messenger RNA (mRNA) through the ribosome.
DNA polymerase alpha catalytic subunit is an enzyme that in humans is encoded by the POLA1 gene.
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