MRPL12 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | MRPL12 , 5c5-2, L12mt, MRP-L31/34, MRPL7, MRPL7/L12, RPML12, mitochondrial ribosomal protein L12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602375 MGI: 1926273 HomoloGene: 2212 GeneCards: MRPL12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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39S ribosomal protein L12, mitochondrial is a protein that in humans is encoded by the MRPL12 gene. [4] [5] [6]
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [6]
28S ribosomal protein S12, mitochondrial is a protein that in humans is encoded by the MRPS12 gene.
28S ribosomal protein L42, mitochondrial is a protein that in humans is encoded by the MRPL42 gene.
39S ribosomal protein L15, mitochondrial is a protein that in humans is encoded by the MRPL15 gene.
28S ribosomal protein S7, mitochondrial is a protein that in humans is encoded by the MRPS7 gene.
28S ribosomal protein S22, mitochondrial is a protein that in humans is encoded by the MRPS22 gene.
39S ribosomal protein L20, mitochondrial is a protein that in humans is encoded by the MRPL20 gene.
28S ribosomal protein S11, mitochondrial is a protein that in humans is encoded by the MRPS11 gene.
39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.
28S ribosomal protein S16, mitochondrial is a protein that in humans is encoded by the MRPS16 gene.
39S ribosomal protein L4, mitochondrial is a protein that in humans is encoded by the MRPL4 gene.
28S ribosomal protein S17, mitochondrial is a protein that in humans is encoded by the MRPS17 gene.
28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.
28S ribosomal protein S6, mitochondrial is a protein that in humans is encoded by the MRPS6 gene.
39S ribosomal protein L32, mitochondrial is a protein that in humans is encoded by the MRPL32 gene.
39S ribosomal protein L24, mitochondrial is a protein that in humans is encoded by the MRPL24 gene.
28S ribosomal protein S18b, mitochondrial is a protein that in humans is encoded by the MRPS18B gene.
28S ribosomal protein S18a, mitochondrial is a protein that in humans is encoded by the MRPS18A gene.
39S ribosomal protein L23, mitochondrial is a protein that in humans is encoded by the MRPL23 gene.
28S ribosomal protein S25, mitochondrial is a protein that in humans is encoded by the MRPS25 gene.
39S ribosomal protein L10, mitochondrial is a protein that in humans is encoded by the MRPL10 gene.