Probable ribosome biogenesis protein RLP24

RSL24D1
Identifiers
Aliases	RSL24D1 , C15orf15, HRP-L30-iso, L30, RLP24, RPL24, RPL24L, TVAS3, ribosomal L24 domain containing 1
External IDs	OMIM: 613262 MGI: 2681840 HomoloGene: 9462 GeneCards: RSL24D1
Gene location (Human) Chr. Chromosome 15 (human) [1] Band 15q21.3 Start 55,180,806 bp [1] End 55,197,049 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 D Start 73,020,708 bp [2] End 73,030,615 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium Achilles tendon parietal pleura tibia ganglionic eminence amniotic fluid secondary oocyte monocyte superficial temporal artery caput epididymis Top expressed in morula neural tube ganglionic eminence yolk sac spermatid spermatocyte placenta thymus mesencephalon ovary More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of ribosome protein binding RNA binding Cellular component cytosolic large ribosomal subunit ribosome nucleolus intracellular anatomical structure nucleus Biological process assembly of large subunit precursor of preribosome protein biosynthesis ribosomal large subunit assembly ribosome biogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51187 225215 Ensembl ENSG00000137876 ENSMUSG00000032215 UniProt Q9UHA3 Q99L28 RefSeq (mRNA) NM_016304 NM_198609 RefSeq (protein) NP_057388 NP_941011 Location (UCSC) Chr 15: 55.18 – 55.2 Mb Chr 9: 73.02 – 73.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable ribosome biogenesis protein RLP24 is a protein that in humans is encoded by the RSL24D1 gene. ^{[5] [6] [7]}

This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000137876 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032215 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Saveanu C, Namane A, Gleizes PE, Lebreton A, Rousselle JC, Noaillac-Depeyre J, Gas N, Jacquier A, Fromont-Racine M (Jun 2003). "Sequential protein association with nascent 60S ribosomal particles". Mol Cell Biol. 23 (13): 4449–60. doi:10.1128/MCB.23.13.4449-4460.2003. PMC   164837 . PMID   12808088.
6. Saveanu C, Bienvenu D, Namane A, Gleizes PE, Gas N, Jacquier A, Fromont-Racine M (Nov 2001). "Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps". EMBO J. 20 (22): 6475–84. doi:10.1093/emboj/20.22.6475. PMC   125736 . PMID   11707418.
7. "Entrez Gene: C15orf15 chromosome 15 open reading frame 15".

External links

• Human RPL24 genome location and RPL24 gene details page in the UCSC Genome Browser .
• Human RSL24D1 genome location and RSL24D1 gene details page in the UCSC Genome Browser .

Further reading

• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC   442147 . PMID   15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.