RRP15

RRP15
Identifiers
Aliases	RRP15 , KIAA0507, CGI-115, ribosomal RNA processing 15 homolog
External IDs	OMIM: 611193 MGI: 1914473 HomoloGene: 32293 GeneCards: RRP15
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q41 Start 218,285,293 bp [1] End 218,337,983 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H5 Start 186,453,175 bp [2] End 186,481,555 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte Achilles tendon germinal epithelium gastrocnemius muscle right ventricle palpebral conjunctiva biceps brachii myocardium amniotic fluid islet of Langerhans Top expressed in primitive streak abdominal wall somite morula hair follicle yolk sac otic placode maxillary prominence Paneth cell interventricular septum More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 51018 67223 Ensembl ENSG00000067533 ENSMUSG00000001305 UniProt Q9Y3B9 Q9CYX7 RefSeq (mRNA) NM_016052 NM_026041 RefSeq (protein) NP_057136 NP_080317 Location (UCSC) Chr 1: 218.29 – 218.34 Mb Chr 1: 186.45 – 186.48 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RRP15-like protein is a protein that in humans is encoded by the RRP15 gene. ^{[5] [6]}

This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000067533 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001305 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. De Marchis ML, Giorgi A, Schinina ME, Bozzoni I, Fatica A (Mar 2005). "Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation". RNA. 11 (4): 495–502. doi:10.1261/rna.7200205. PMC   1370738 . PMID   15769876.
6. "Entrez Gene: RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC   310876 . PMID   10810093.
• Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi: 10.1093/dnares/4.5.345 . PMID   9455484.