Occipital lobe

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Occipital lobe
Lobes of the human brain (the occipital lobe is shown in red)
Gray727 occipital lobe.png
Medial surface of left cerebral hemisphere. (Cuneus and lingual gyrus are at left.)
Details
Part of Cerebrum
Artery Posterior cerebral artery
Identifiers
Latin lobus occipitalis
MeSH D009778
NeuroNames 140
NeuroLex ID birnlex_1136
TA98 A14.1.09.132
TA2 5480
FMA 67325
Anatomical terms of neuroanatomy

The occipital lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The name derives from its position at the back of the head, from the Latin ob, 'behind', and caput, 'head'.

Contents

The occipital lobe is the visual processing center of the mammalian brain containing most of the anatomical region of the visual cortex. [1] The primary visual cortex is Brodmann area 17, commonly called V1 (visual one). Human V1 is located on the medial side of the occipital lobe within the calcarine sulcus; the full extent of V1 often continues onto the occipital pole. V1 is often also called striate cortex because it can be identified by a large stripe of myelin, the stria of Gennari. Visually driven regions outside V1 are called extrastriate cortex. There are many extrastriate regions, and these are specialized for different visual tasks, such as visuospatial processing, color differentiation, and motion perception. Bilateral lesions of the occipital lobe can lead to cortical blindness (see Anton's syndrome).

Structure

Diagram of gyri of brain viewed on lateral hemisphere. Occipital gyri shown lower right Gyri of lateral cortex.png
Diagram of gyri of brain viewed on lateral hemisphere. Occipital gyri shown lower right
Animation. Occipital lobe (red) of left cerebral hemisphere. Occipital lobe animation small.gif
Animation. Occipital lobe (red) of left cerebral hemisphere.

The two occipital lobes are the smallest of four paired lobes in the human brain. Located in the rearmost portion of the skull, the occipital lobes are part of the posterior cerebrum. The lobes of the brain are named from the overlying bone and the occipital bone overlies the occipital lobes.

The lobes rest on the tentorium cerebelli, a process of dura mater that separates the cerebrum from the cerebellum. They are structurally isolated in their respective cerebral hemispheres by the separation of the cerebral fissure. At the front edge of the occipital lobe are several occipital gyri, which are separated by lateral occipital sulcus.

The occipital aspects along the inside face of each hemisphere are divided by the calcarine sulcus. Above the medial, Y-shaped sulcus lies the cuneus, and the area below the sulcus is the lingual gyrus.

Damage to the primary visual areas of the occipital lobe can cause partial or complete blindness. [2]

Function

The occipital lobe is divided into several functional visual areas. Each visual area contains a full map of the visual world. Although there are no anatomical markers distinguishing these areas (except for the prominent striations in the striate cortex), physiologists have used electrode recordings to divide the cortex into different functional regions.[ citation needed ]

The first functional area is the primary visual cortex. It contains a low-level description of the local orientation, spatial-frequency and color properties within small receptive fields. Primary visual cortex projects to the occipital areas of the ventral stream (visual area V2 and visual area V4), and the occipital areas of the dorsal streamvisual area V3, visual area MT (V5), and the dorsomedial area (DM).

The ventral stream is known for processing the "what" in vision, while the dorsal stream handles the "where/how". This is because the ventral stream provides important information for the identification of stimuli that are stored in memory. With this information in memory, the dorsal stream is able to focus on motor actions in response to the outside stimuli.

Although numerous studies have shown that the two systems are independent and structured separately from another, there is also evidence that both are essential for successful perception, especially as the stimuli take on more complex forms. For example, a case study using fMRI was done on shape and location. The first procedure consisted of location tasks. The second procedure was in a lit-room where participants were shown stimuli on a screen for 600 ms. They found that the two pathways play a role in shape perception even though location processing continues to lie within the dorsal stream. [3]

The dorsomedial (DM) is not as thoroughly studied. However, there is some evidence that suggests that this stream interacts with other visual areas. A case study on monkeys revealed that information from V1 and V2 areas make up half the inputs in the DM. The remaining inputs are from multiple sources that have to do with any sort of visual processing [4]

A significant functional aspect of the occipital lobe is that it contains the primary visual cortex.[ citation needed ]

Retinal sensors convey stimuli through the optic tracts to the lateral geniculate bodies, where optic radiations continue to the visual cortex. Each visual cortex receives raw sensory information from the outside half of the retina on the same side of the head and from the inside half of the retina on the other side of the head. The cuneus (Brodmann's area 17) receives visual information from the contralateral superior retina representing the inferior visual field. The lingula receives information from the contralateral inferior retina representing the superior visual field. The retinal inputs pass through a "way station" in the lateral geniculate nucleus of the thalamus before projecting to the cortex. Cells on the posterior aspect of the occipital lobes' gray matter are arranged as a spatial map of the retinal field. Functional neuroimaging reveals similar patterns of response in cortical tissue of the lobes when the retinal fields are exposed to a strong pattern.

Clinical significance

If one occipital lobe is damaged, the result can be homonymous hemianopsia vision loss from similarly positioned "field cuts" in each eye. Occipital lesions can cause visual hallucinations. Lesions in the parietal-temporal-occipital association area are associated with color agnosia, movement agnosia, and agraphia. Lesions near the left occipital lobe can result in pure alexia (alexia without agraphia). Damage to the primary visual cortex, which is located on the surface of the posterior occipital lobe, can cause blindness due to the holes in the visual map on the surface of the visual cortex that resulted from the lesions. [5]

Epilepsy

Recent studies have shown that specific neurological findings have affected idiopathic occipital lobe epilepsies. [6] Occipital lobe seizures are triggered by a flash, or a visual image that contains multiple colors. These are called flicker stimulation (usually through TV) these seizures are referred to as photo-sensitivity seizures. Patients having experienced occipital seizures described their seizures as featuring bright colors, and severely blurring their vision (vomiting was also apparent in some patients). Occipital seizures are triggered mainly during the day, through television, video games or any flicker stimulatory system. [7] Occipital seizures originate from an epileptic focus confined within the occipital lobes. They may be spontaneous or triggered by external visual stimuli. Occipital lobe epilepsies are etiologically idiopathic, symptomatic, or cryptogenic. [8] Symptomatic occipital seizures can start at any age, as well as any stage after or during the course of the underlying causative disorder. Idiopathic occipital epilepsy usually starts in childhood. [8] Occipital epilepsies account for approximately 5% to 10% of all epilepsies. [8]

Additional images

See also

Related Research Articles

<span class="mw-page-title-main">Visual cortex</span> Region of the brain that processes visual information

The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 (V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5.

Blindsight is the ability of people who are cortically blind to respond to visual stimuli that they do not consciously see due to lesions in the primary visual cortex, also known as the striate cortex or Brodmann Area 17. The term was coined by Lawrence Weiskrantz and his colleagues in a paper published in a 1974 issue of Brain. A previous paper studying the discriminatory capacity of a cortically blind patient was published in Nature in 1973. The assumed existence of blindsight is controversial, with some arguing that it is merely degraded conscious vision.

<span class="mw-page-title-main">Visual system</span> Body parts responsible for vision

The visual system is the physiological basis of visual perception. The system detects, transduces and interprets information concerning light within the visible range to construct an image and build a mental model of the surrounding environment. The visual system is associated with the eye and functionally divided into the optical system and the neural system.

<span class="mw-page-title-main">Sensory nervous system</span> Part of the nervous system

The sensory nervous system is a part of the nervous system responsible for processing sensory information. A sensory system consists of sensory neurons, neural pathways, and parts of the brain involved in sensory perception and interoception. Commonly recognized sensory systems are those for vision, hearing, touch, taste, smell, balance and visceral sensation. Sense organs are transducers that convert data from the outer physical world to the realm of the mind where people interpret the information, creating their perception of the world around them.

<span class="mw-page-title-main">Parietal lobe</span> Part of the brain responsible for sensory input and some language processing

The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus.

<span class="mw-page-title-main">Brodmann area 19</span>

Brodmann area 19, or BA 19, is part of the occipital lobe cortex in the human brain. Along with area 18, it comprises the extrastriate cortex. In humans with normal sight, extrastriate cortex is a visual association area, with feature-extracting, shape recognition, attentional, and multimodal integrating functions.

<span class="mw-page-title-main">Optic radiation</span> Neural pathway in the visual system

In neuroanatomy, the optic radiation are axons from the neurons in the lateral geniculate nucleus to the primary visual cortex. The optic radiation receives blood through deep branches of the middle cerebral artery and posterior cerebral artery.

<span class="mw-page-title-main">Lobes of the brain</span> Parts of the cerebrum

The lobes of the brain are the major identifiable zones of the human cerebral cortex, and they comprise the surface of each hemisphere of the cerebrum. The two hemispheres are roughly symmetrical in structure, and are connected by the corpus callosum. They traditionally have been divided into four lobes, but are today considered as having six lobes each. The lobes are large areas that are anatomically distinguishable, and are also functionally distinct to some degree. Each lobe of the brain has numerous ridges, or gyri, and furrows, the sulci that constitute further subzones of the cortex. The expression "lobes of the brain" usually refers only to those of the cerebrum, not to the distinct areas of the cerebellum.

<span class="mw-page-title-main">Cuneus</span> Region in the occipital lobe of the brain

The cuneus is a smaller lobe in the occipital lobe of the brain. The cuneus is bounded anteriorly by the parieto-occipital sulcus and inferiorly by the calcarine sulcus.

<span class="mw-page-title-main">Retinotopy</span> Mapping of visual input from the retina to neurons

Retinotopy is the mapping of visual input from the retina to neurons, particularly those neurons within the visual stream. For clarity, 'retinotopy' can be replaced with 'retinal mapping', and 'retinotopic' with 'retinally mapped'.

<span class="mw-page-title-main">Posterior cerebral artery</span> Artery which supplies blood to the occipital lobe of the brain

The posterior cerebral artery (PCA) is one of a pair of cerebral arteries that supply oxygenated blood to the occipital lobe, part of the back of the human brain. The two arteries originate from the distal end of the basilar artery, where it bifurcates into the left and right posterior cerebral arteries. These anastomose with the middle cerebral arteries and internal carotid arteries via the posterior communicating arteries.

<span class="mw-page-title-main">Inferior temporal gyrus</span> One of three gyri of the temporal lobe of the brain

The inferior temporal gyrus is one of three gyri of the temporal lobe and is located below the middle temporal gyrus, connected behind with the inferior occipital gyrus; it also extends around the infero-lateral border on to the inferior surface of the temporal lobe, where it is limited by the inferior sulcus. This region is one of the higher levels of the ventral stream of visual processing, associated with the representation of objects, places, faces, and colors. It may also be involved in face perception, and in the recognition of numbers and words.

<span class="mw-page-title-main">Colour centre</span> Brain region responsible for colour processing

The colour centre is a region in the brain primarily responsible for visual perception and cortical processing of colour signals received by the eye, which ultimately results in colour vision. The colour centre in humans is thought to be located in the ventral occipital lobe as part of the visual system, in addition to other areas responsible for recognizing and processing specific visual stimuli, such as faces, words, and objects. Many functional magnetic resonance imaging (fMRI) studies in both humans and macaque monkeys have shown colour stimuli to activate multiple areas in the brain, including the fusiform gyrus and the lingual gyrus. These areas, as well as others identified as having a role in colour vision processing, are collectively labelled visual area 4 (V4). The exact mechanisms, location, and function of V4 are still being investigated.

The Riddoch syndrome is a term coined by Zeki and Ffytche (1998) in a paper published in Brain. The term acknowledges the work of George Riddoch who was the first to describe a condition in which a form of visual impairment, caused by lesions in the occipital lobe, leaves the sufferer blind but able to distinguish visual stimuli with specific characteristics when these appear in the patient's blind field. The most common stimuli that can be perceived consciously are the presence and direction of fast moving objects ; in his work these moving objects were described as "vague and shadowy". Riddoch concluded from his observations that "movement may be recognized as a special visual perception".

The neuroanatomy of memory encompasses a wide variety of anatomical structures in the brain.

Cortical stimulation mapping (CSM) is a type of electrocorticography that involves a physically invasive procedure and aims to localize the function of specific brain regions through direct electrical stimulation of the cerebral cortex. It remains one of the earliest methods of analyzing the brain and has allowed researchers to study the relationship between cortical structure and systemic function. Cortical stimulation mapping is used for a number of clinical and therapeutic applications, and remains the preferred method for the pre-surgical mapping of the motor cortex and language areas to prevent unnecessary functional damage. There are also some clinical applications for cortical stimulation mapping, such as the treatment of epilepsy.

Form perception is the recognition of visual elements of objects, specifically those to do with shapes, patterns and previously identified important characteristics. An object is perceived by the retina as a two-dimensional image, but the image can vary for the same object in terms of the context with which it is viewed, the apparent size of the object, the angle from which it is viewed, how illuminated it is, as well as where it resides in the field of vision. Despite the fact that each instance of observing an object leads to a unique retinal response pattern, the visual processing in the brain is capable of recognizing these experiences as analogous, allowing invariant object recognition. Visual processing occurs in a hierarchy with the lowest levels recognizing lines and contours, and slightly higher levels performing tasks such as completing boundaries and recognizing contour combinations. The highest levels integrate the perceived information to recognize an entire object. Essentially object recognition is the ability to assign labels to objects in order to categorize and identify them, thus distinguishing one object from another. During visual processing information is not created, but rather reformatted in a way that draws out the most detailed information of the stimulus.

<span class="mw-page-title-main">Disconnection syndrome</span> Collection of neurological symptoms

Disconnection syndrome is a general term for a collection of neurological symptoms caused – via lesions to associational or commissural nerve fibres – by damage to the white matter axons of communication pathways in the cerebrum, independent of any lesions to the cortex. The behavioral effects of such disconnections are relatively predictable in adults. Disconnection syndromes usually reflect circumstances where regions A and B still have their functional specializations except in domains that depend on the interconnections between the two regions.

Cerebral diplopia or polyopia describes seeing two or more images arranged in ordered rows, columns, or diagonals after fixation on a stimulus. The polyopic images occur monocular bilaterally and binocularly, differentiating it from ocular diplopia or polyopia. The number of duplicated images can range from one to hundreds. Some patients report difficulty in distinguishing the replicated images from the real images, while others report that the false images differ in size, intensity, or color. Cerebral polyopia is sometimes confused with palinopsia, in which multiple images appear while watching an object. However, in cerebral polyopia, the duplicated images are of a stationary object which are perceived even after the object is removed from the visual field. Movement of the original object causes all of the duplicated images to move, or the polyopic images disappear during motion. In palinoptic polyopia, movement causes each polyopic image to leave an image in its wake, creating hundreds of persistent images (entomopia).

<span class="mw-page-title-main">Occipital epilepsy</span> Medical condition

Occipital epilepsy is a neurological disorder that arises from excessive neural activity in the occipital lobe of the brain that may or may not be symptomatic. Occipital lobe epilepsy is fairly rare, and may sometimes be misdiagnosed as migraine when symptomatic. Epileptic seizures are the result of synchronized neural activity that is excessive, and may stem from a failure of inhibitory neurons to regulate properly.

References

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  2. Schacter, D. L., Gilbert, D. L. & Wegner, D. M. (2009). Psychology. (2nd ed.). New York: Worth Publishers.
  3. Valyear, Culham, Sharif, Westwood, & Goodale, 2006.
  4. Valyear et al., 2006.
  5. Carlson, Neil R. (2007). Psychology : the science of behaviour. New Jersey, USA: Pearson Education. pp.  115. ISBN   978-0-205-64524-4.
  6. Chilosi, Anna Maria; Brovedani (November 2006). "Neuropsychological Findings in Idiopathic Occipital Lobe Epilepsies". Epilepsia. 47 (s2): 76–78. doi:10.1111/j.1528-1167.2006.00696.x. PMID   17105468. S2CID   23702191.
  7. Destina Yalçin, A.; Kaymaz, A.; Forta, H. (2000). "Reflex occipital lobe epilepsy". Seizure. 9 (6): 436–441. doi: 10.1053/seiz.2000.0424 . PMID   10986003.
  8. 1 2 3 Adcock, Jane E; Panayiotopoulos, Chrysostomos P (31 October 2012). "Journal of Clinical Neurophysiology". Occipital Lobe Seizures and Epilepsies. 29 (5): 397–407. doi:10.1097/wnp.0b013e31826c98fe. PMID   23027097.