George Bellows (1882–1925), realist painter, known for bold depictions of urban life in New York City, becoming, according to Columbus Museum of Art, "the most acclaimed American artist of his generation"
Charles Csuri (1922–2022), father of digital art and computer animation
Archie Griffin (1954– ), only two-time Heisman Trophy winner; attended Eastmoor High School, then the Ohio State University; won the Heisman Trophy twice as a running back for the OSU Buckeyes; returned to Columbus after his pro career to become the university's assistant athletic director, and president of its alumni association
Jack Nicklaus (1940– ), pro golfer, winner of a record 18 golfmajors and member of World Golf Hall of Fame; born in Columbus and attended the Ohio State University; won the 1961 NCAA Championship while playing for the school
Roosevelt Nix (1992– ), NFL fullback for the Pittsburgh Steelers; born and raised in Columbus; attended high school in Reynoldsburgh and played college football at Kent State
Jesse Owens (1913–1980), track and field; set three world records in one day while in college at the Ohio State University; won four gold medals at the 1936 Olympics; raised in Cleveland, and attended college in Columbus
Gary Trent (1974– ), NBA player; attended Hamilton Township High School and was born and raised in Columbus
Louie Vito (1988– ), professional snowboarder, 2010 US Olympic Team, four-time Overall US Grand Prix Champion and two-time Dew Cup Overall Champion; six career X Games medals, including two gold medals; born in Columbus
Granville Waiters (1961–2021), NBA player; born and raised in Columbus
Samaki Walker (1976– ), NBA player; born and raised in Columbus
Evan White (1996– ), Major League Baseball player; born in Columbus
Herb Williams (1958– ), NBA player and coach; born in Columbus and played basketball for the Ohio State University
Jarren Williams (1997– ), NFL defensive back for New York Giants; born and raised in Columbus
Gilbert C. Hoover (1894–1980), World War I and World War II USN admiral, involved in developing the nuclear bomb
Curtis LeMay (1906–1990), World War II and Cold War U.S. Air Force general; born and raised in Columbus; studied civil engineering at the Ohio State University
Irvin McDowell (1818–1885), army officer; born in Columbus
Harold "Sweets" Edison (1915–1999), jazz trumpeter of the swing/bebop era who played and recorded with Coleman Hawkins, Ben Webster, and Count Basie; born in Columbus and attended East High School
FanFan (范玮琪) (1976– ), Taiwanese-American artist; born in Columbus
Phil Ochs (1940–1976), folk-activist singer and songwriter; grew up in Columbus, which provided the inspiration for his song "Boy in Ohio"; studied journalism at Ohio State University
Jermaine Stewart, an American R&B singer best known for his 1986 hit single "We Don't Have to Take Our Clothes Off", which peaked at number five on the Billboard Hot 100. Born in Columbus.
Dwight Yoakam (1956– ), country singer; raised in Columbus and briefly attended Ohio State
Politicians
Prescott Bush (1895–1972), U.S. Senator elected from Connecticut, father and grandfather of Presidents George H. W. Bush and George W. Bush, respectively; born in Columbus and spent his childhood there until 1908; moved back to Columbus for part of 1923 for a job in business
Harvey C. Mansfield, Jr. (1932– ), Professor of Government at Harvard University; author of numerous books on the subject of political theory; graduated from high school in Columbus[9]
Maggie Smith, poet, freelance writer, and editor, born in Columbus
Donald Ogden Stewart (1894–1980), humorist, playwright, and Academy Award-winning black-listed screenwriter; born and raised in Columbus
R. L. Stine (1943– ), author; born and raised in Columbus; attended the Ohio State University
James Thurber (1894–1961), cartoonist and humorist; born and raised in Columbus; many of his short stories depict episodes from this period of his life
Judah Folkman (1933–2008), medical scientist who founded the field of angiogenesis research; raised in Columbus, and graduated from the Ohio State University
Ruth Ella Moore (1903–1994), academician, bacteriologist, microbiologist, and fashion designer, born in Columbus, awarded a Ph.D. of historical note in 1933 by Ohio State University, professor and department chair at Howard University [12]
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