Clobetasone butyrate

Clobetasone butyrate

Clinical data
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name (16β)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate
CAS Number	25122-57-0
ChemSpider	64481
UNII	8U0H6XI6EO
CompTox Dashboard (EPA)	DTXSID3046823
ECHA InfoCard	100.042.381
Chemical and physical data
Formula	C26H32ClFO5
Molar mass	478.99 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(CC(=O)[C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)C)C)C(=O)CCl
InChI InChI=1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1 Key:FBRAWBYQGRLCEK-AVVSTMBFSA-N

Clobetasone butyrate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester that is used in the treatment of skin disorders such as eczema and psoriasis. ^[1]

References

1. Goustas P, Cork MJ, Higson D (June 2003). "Eumovate (clobetasone butyrate 0.05%) cream: a review of clinical efficacy and safety". The Journal of Dermatological Treatment. 14 (2): 71–85. doi:10.1080/09546630310004180. PMID   12775314.