Clinical data | |
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Trade names | Flutenal |
Other names | UR-105; Triamcinolone acetonide metembonate; 4,4'-Methylene-bis((9α-fluoro-11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione)3-methoxy-2-naphthoate); 21,21'-[Methylenebis[(2-methoxy-1,3-naphthalenediyl)- carbonyloxy]]bis[9α-fluoro-11β-hydroxy-16α,17α-[(1-methylethylidene)- bis(oxy)]pregna-1,4-diene-3,20-dione |
Routes of administration | Topical [1] |
Drug class | Corticosteroid; Glucocorticoid |
Identifiers | |
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CAS Number | |
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UNII | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.054.209 |
Chemical and physical data | |
Formula | C73H78F2O16 |
Molar mass | 1249.408 g·mol−1 |
3D model (JSmol) | |
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Flupamesone (brand name Flutenal), also known as triamcinolone acetonide metembonate, is a synthetic glucocorticoid corticosteroid which is marketed in Spain. [2] [3] [4] [1] It is a dimer of a C21 ester of triamcinolone acetonide. [2] [3] [1]
ATC code D07Corticosteroids, dermatological preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. Subgroup D07 is part of the anatomical group D Dermatologicals.
Triamcinolone is a glucocorticoid used to treat certain skin diseases, allergies, and rheumatic disorders among others. It is also used to prevent worsening of asthma and COPD. It can be taken in various ways including by mouth, injection into a muscle, and inhalation.
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions. It is also injected into lesions to treat inflammation in some parts of the body, particularly the skin. In nasal spray form, it is used to treat allergic rhinitis. It is used for the treatment of macular edema associated with uveitis. It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone.
Triamcinolone hexacetonide is a synthetic glucocorticoid corticosteroid.
Fluocinolone is a synthetic glucocorticoid corticosteroid which was never marketed. The acetonide cyclic ketal of fluocinolone, fluocinolone acetonide, in contrast, has been marketed.
Triamcinolone furetonide is a synthetic glucocorticoid corticosteroid which was never marketed.
Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid.
Fluclorolone is a synthetic glucocorticoid corticosteroid which was never marketed. The acetonide cyclic ketal of fluclorolone, fluclorolone acetonide, in contrast, has been marketed.
Algestone acetonide, also known as algestone 16α,17α-acetonide or 16α,17α-isopropylidenedioxyprogesterone, is a progestin which was never marketed. It is the acetonide cyclic ketal of algestone. Another progestin, algestone acetophenide, in contrast, has been marketed.
Amcinafal, also known as triamcinolone pentanonide, is a synthetic glucocorticoid corticosteroid which was never marketed.
Amcinafide, also known as triamcinolone acetophenide, is a synthetic glucocorticoid corticosteroid which was never marketed.
Descinolone acetonide, also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid corticosteroid which was never marketed.
Triamcinolone aminobenzal benzamidoisobutyrate is a synthetic glucocorticoid corticosteroid which is no longer marketed.
In organic chemistry, acetophenide is a functional group which is composed of the cyclic ketal of a diol with acetophenone. In pharmaceutical chemistry, it is present in algestone acetophenide and amcinafide.
In organic chemistry, acroleinide is a functional group which is composed of a cyclic ketal of a diol with acrolein. In pharmaceutical chemistry, it is present in acrocinonide.
In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal.
In organic chemistry, cyclopentanonide is a functional group which is composed of a cyclic ketal of a diol with cyclopentanone. It is seen in amcinonide.
In organic chemistry, aminobenzal is a functional group which is composed of a cyclic ketal of a diol with 4-dimethylaminobenzylidene. It is seen in triamcinolone aminobenzal benzamidoisobutyrate.