Tralonide

Tralonide
Clinical data
Trade names	Talidan
Other names	6α,21-Difluoro-9α,11β-dichloro-16α,17α-dihydroxypregna-1,4-diene-3,20-dione 16,17-acetonide; 6α,21-Difluoro-9α,11β-dichloro-16α,17α-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,5-Dichloro-12-fluoro-6b-(fluoroacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one;
CAS Number	21365-49-1 ;
PubChem CID	20055296 ;
UNII	38ETX8IT42 ;
KEGG	D06201 ;
ChEMBL	ChEMBL2105543 ;
CompTox Dashboard (EPA)	DTXSID60175627 ;
Chemical and physical data
Formula	C24H28Cl2F2O4
Molar mass	489.38 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CF)C)Cl)Cl)C)F)C;
	InChI InChI=1S/C24H28Cl2F2O4/c1-20(2)31-19-9-13-14-8-16(28)15-7-12(29)5-6-21(15,3)23(14,26)17(25)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1; Key:OGZHZYVCWDUIJV-VSXGLTOVSA-N;

Last updated August 31, 2025

Tralonide (brand name Talidan) is a synthetic glucocorticoid corticosteroid.^[1]^[2]

References

↑ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 3296–. ISBN 978-0-8155-1856-3.
↑ Scherrer R (2 December 2012). Anti-inflammatory Agents Part I: Chemistry and Pharmacology. Elsevier Science. pp. 267–. ISBN 978-0-323-15015-6.

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[Publishing2013-1] William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 3296–. ISBN 978-0-8155-1856-3.

[Scherrer2012-2] Scherrer R (2 December 2012). Anti-inflammatory Agents Part I: Chemistry and Pharmacology. Elsevier Science. pp. 267–. ISBN 978-0-323-15015-6.

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[2]