Fluperolone acetate

Fluperolone acetate
Clinical data
Other names	9α-Fluoro-11β,17α,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione 21-acetate
ATC code	D07AB05 ( WHO );
Identifiers
	IUPAC name (2S)-1-[(1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-1-oxopropan-2-yl acetate;
CAS Number	2119-75-7 ;
PubChem CID	66257 ;
ChemSpider	59639 ;
UNII	DOL7Q9DPF9 ;
KEGG	D04225 ;
CompTox Dashboard (EPA)	DTXSID50895064 ;
ECHA InfoCard	100.016.662
Chemical and physical data
Formula	C24H31FO6
Molar mass	434.504 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES C[C@@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)OC(=O)C;
	InChI InChI=1S/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1; Key:HHPZZKDXAFJLOH-QZIXMDIESA-N;
	(verify)

Last updated December 31, 2025

Fluperolone acetate is a corticosteroid. It has been used topically.^[1]

References

↑ Thorne N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgraduate Medical Journal. 39 (449): 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046 . PMID 13984971.

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[pmid13984971-1] Thorne N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgraduate Medical Journal. 39 (449): 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046 . PMID 13984971.

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