Fluocortin

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Fluocortin
Fluocortin.svg
Clinical data
Other names6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20,21-trione
ATC code
Pharmacokinetic data
Bioavailability 80% i.v.
Elimination half-life 1.3 hr.
Identifiers
  • 2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-Fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.046.698 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C22H27FO5
Molar mass 390.451 g·mol−1
3D model (JSmol)
  • C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)C(=O)O)C)O)C)F
  • InChI=1S/C22H27FO5/c1-10-6-13-12-8-15(23)14-7-11(24)4-5-21(14,2)18(12)16(25)9-22(13,3)17(10)19(26)20(27)28/h4-5,7,10,12-13,15-18,25H,6,8-9H2,1-3H3,(H,27,28)/t10-,12+,13+,15+,16+,17-,18-,21+,22+/m1/s1
  • Key:PUWHHWCHAVXSIG-NCLPIGKXSA-N
   (verify)

Fluocortin is a corticosteroid. It is similar to fluocortolone, but with one more keto group. [1]

Related Research Articles

Corticosteroid Class of steroid hormones

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.

ATC code C05Vasoprotectives is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. Subgroup C05 is part of the anatomical group C Cardiovascular system.

ATC code H02Corticosteroids for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. Subgroup H02 is part of the anatomical group H Systemic hormonal preparations, excluding sex hormones and insulins.

Fluocortolone

Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.

Guided bone regeneration (GBR) and guided tissue regeneration (GTR) are dental surgical procedures that use barrier membranes to direct the growth of new bone and gingival tissue at sites with insufficient volumes or dimensions of bone or gingiva for proper function, esthetics or prosthetic restoration. Guided bone regeneration typically refers to ridge augmentation or bone regenerative procedures; guided tissue regeneration typically refers to regeneration of periodontal attachment.

Topical steroids are the topical forms of corticosteroids. Topical steroids are the most commonly prescribed topical medications for the treatment of rash, eczema, and dermatitis. Topical steroids have anti-inflammatory properties, and are classified based on their skin vasoconstrictive abilities. There are numerous topical steroid products. All the preparations in each class have the same anti-inflammatory properties, but essentially differ in base and price.

The molecular formula C22H29FO4 (molar mass: 376.46 g/mol) may refer to:

References

  1. ↑ Täuber U, Haack D, Nieuweboer B, Kloss G, Vecsei P, Wendt H (January 1984). "The pharmacokinetics of fluocortolone and prednisolone after intravenous and oral administration". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 22 (1): 48–55. PMID   6698661.
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