Fluprednisolone

Last updated
Fluprednisolone
Fluprednisolone.svg
Fluprednisolone 3D ball.png
Names
IUPAC name
6α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Systematic IUPAC name
(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-Fluoro-1,10-dihydroxy-1-(hydroxyacetyl)-9a,11a-dimethyl-1,2,3,3a,3b,4,5,9a,9b,10,11,11a-dodecahydro-7H-cyclopenta[a]phenanthren-7-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.000.156 OOjs UI icon edit-ltr-progressive.svg
KEGG
PubChem CID
UNII
  • InChI=1S/C21H27FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7,12-13,15-16,18,23,25,27H,4,6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1 X mark.svgN
    Key: MYYIMZRZXIQBGI-HVIRSNARSA-N X mark.svgN
  • InChI=1/C21H27FO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7,12-13,15-16,18,23,25,27H,4,6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1
    Key: MYYIMZRZXIQBGI-HVIRSNARBK
  • C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@@H](C4=CC(=O)C=C[C@]34C)F)O
Properties
C21H27FO5
Molar mass 378.43 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Fluprednisolone is a pregnane. It is a corticosteroid. [1]

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References

  1. Naggar VF, Gouda MW, Khalil SA (December 1977). "In vitro adsorption of some corticosteroids on antacids". Pharmazie. 32 (12): 778–81. PMID   613316.