Tipredane

Last updated
Tipredane
Tipredane.svg
Clinical data
Other namesSQ-27239; 17α-(Ethylthio)-9α-fluoro-11β-hydroxy-20-thiapregn-1,4-diene-3-one; 17α-(Ethylthio)-9α-fluoro-11β-hydroxy-17-(methylthio)androsta-1,4-dien-3-one
Drug class Corticosteroid; Glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
Formula C22H31FO2S2
Molar mass 410.61 g·mol−1
3D model (JSmol)

Tipredane (developmental code name SQ-27239) is a synthetic glucocorticoid corticosteroid which was never marketed. [1] [2]

Related Research Articles

General Secretary of the Communist Party of the Soviet Union De facto Leader of the Soviet Union

The General Secretary of the Central Committee of the Communist Party of the Soviet Union was an office of the Communist Party of the Soviet Union (CPSU) that by the late 1920s had evolved into the most powerful of the Central Committee's various secretaries. With a few exceptions, from 1929 until the union's dissolution the holder of the office was the de facto leader of the Soviet Union, because the post controlled both the CPSU and the Soviet government. Joseph Stalin elevated the office to overall command of the Communist Party and by extension the whole Soviet Union. Nikita Khrushchev renamed the post First Secretary in 1953; the change was reverted in 1966.

Voiced retroflex flap Consonantal sound

The voiced retroflex flap is a type of consonantal sound, used in some spoken languages. The symbol in the International Phonetic Alphabet that represents this sound is ⟨ɽ⟩, and the equivalent X-SAMPA symbol is r`.

Talbutal

Talbutal (Lotusate) is a barbiturate with a short to intermediate duration of action. It is a structural isomer of butalbital. Talbutal is a schedule III drug in the U.S.

Teniposide

Teniposide is a chemotherapeutic medication used in the treatment of childhood acute lymphocytic leukemia (ALL), Hodgkin's lymphoma, certain brain tumours, and other types of cancer. It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body.

Methylergometrine

Methylergometrine is a synthetic analogue of ergometrine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergometrine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams, due to its agonistic action at the 5HT2A-mGlu2 receptor protomers. Clinical efficacy occurs around 200 µg, ten times lower than the hallucinogenic threshold.

The acid mantle is a very fine, slightly acidic film on the surface of human skin acting as a barrier to bacteria, viruses and other potential contaminants that might penetrate the skin. Sebum is secreted by the sebaceous gland and when mixed with sweat becomes the acid mantle. The pH of the skin is between 4.5 and 6.2, slightly acidic. Since blood is slightly alkaline (7.4), pathogenic bacteria that become adapted to the pH of the skin and are able to reach internal tissues will encounter an environment to which they are less well adapted. This combination of acidic exterior and alkaline interior is one of the body's non-specific host defenses against bacterial pathogens.

SM <i>U-9</i>

SM U-9 was a German Type U 9 U-boat. She was one of 329 submarines serving in the Imperial German Navy, and engaged in commerce raiding (Handelskrieg) during World War I.

Swedish invasion of Russia

The invasion of Russia by Charles XII of Sweden was a campaign undertaken during the Great Northern War between Sweden and the allied states of Russia, Poland, and Denmark. The invasion began with Charles's crossing of the Vistula on 1 January 1708, and effectively ended with the Swedish defeat in the Battle of Poltava on 8 July 1709, though Charles continued to pose a military threat to Russia for several years while under the protection of the Ottoman Turks.

Vestgrensa (station) Former Oslo metro station

Vestgrensa was a light rail station on the Sognsvann Line of the Oslo Metro in Norway. It opened on 10 October 1934, and was located between Blindern and Ullevål stadion stations. The station was rebuilt when the Sognsvann Line was upgraded from light rail to metro standard in the early 1990s. It was closed on 22 August 1999, when it was replaced by the new station Forskningsparken.

A cuckold is the husband of an adulterous wife; the wife of an adulterous husband is a cuckquean. In evolutionary biology, a cuckold is a male which unwittingly invests parental effort in juveniles that are not genetically his offspring.

Milton Kort (1917–2003) was an American professional pharmacist, but dabbled in sleight of hand.

East Asia Eastern region of Asia

East Asia is the eastern region of Asia, which is defined in both geographical and ethno-cultural terms. The modern states of East Asia include China, Hong Kong, Japan, Macau, Mongolia, North Korea, South Korea and Taiwan. The East Asian states of China, North Korea, South Korea and Taiwan are all unrecognized by at least one other East Asian state due to severe ongoing political tensions in the region, specifically the division of Korea and the political status of Taiwan. Hong Kong and Macau, two small coastal quasi-dependent territories located in the south of China, are officially highly autonomous but are under de jure Chinese sovereignty. North Asia borders East Asia's north, Southeast Asia the south, South Asia the southwest and Central Asia the west. To the east is the Pacific Ocean and to the southeast is Micronesia. Singapore and Vietnam are also considered a part of the East Asian cultural sphere due to its cultural, religious, and ethnic similarities. Singapore was also one of the Four Asian Tigers.

Berthold Korts

Berthold Korts was a World War II Luftwaffe fighter ace and was credited with 113 aerial victories—that is, 113 aerial combat encounters resulting in the destruction of the enemy aircraft. He was also a recipient of the Knight's Cross of the Iron Cross, the highest award in the military and paramilitary forces of Nazi Germany during World War II.

Körting Hannover

Körting Hannover AG is a long-standing industrial engineering company in Hanover.

Philippi's law refers to a sound rule in Biblical Hebrew first identified by F.W.M. Philippi in 1878, but has since been refined by Thomas O. Lambdin.

Norsemans Knock Classic Swedish card game

Norseman's Knock or Norrlandsknack is a classic Swedish card game for 3 to 5 players, known since the mid-1800s. It is traditionally played for money. The game is about winning as many tricks as possible and above all not being completely left without a trick.

Femkort

Femkort is a classic Swedish card game for 3 to 8 players "with an unusual object", known since the 17th century. It is traditionally played with some kind of bet.

Rödskägg Swedish card game

Rödskägg ("Redbeard") also called Fem Opp, is a Swedish card game for three to seven players in which penalties are incurred for failing to follow certain rituals as well as for failing to take a declared number of tricks. Some rules describe Fem Opp as a variant of Rödskägg. It is an advanced and tactically demanding game and, of games played in Sweden, only Bridge and Poker are considered more difficult.

Byggkasino is a Swedish development of the old English card game of Casino. Like the latter, the aim of Byggkasino is to capture cards laid out on the table by matching them with cards in the hand that have corresponding numerical values.

References

  1. Rainsford KD, Velo GP (6 December 2012). New Developments in Antirheumatic Therapy. Springer Science & Business Media. pp. 154, 164. ISBN   978-94-009-1253-3.
  2. Korting HC, Schafer-Korting M (24 July 1998). The Benefit/Risk Ratio: A Handbook for the Rational Use of Potentially Hazardous Drugs. CRC Press. pp. 363–. ISBN   978-1-4398-0591-6.