Delayed ejaculation

Last updated
Delayed ejaculation
Other namesRetarded ejaculation, inhibited ejaculation
Specialty Urology

Delayed ejaculation (DE) is a man's inability or persistent difficulty in achieving orgasm, despite typical sexual desire and sexual stimulation. Generally, a man can reach orgasm within a few minutes of active thrusting during sexual intercourse, whereas a man with delayed ejaculation either does not have orgasms at all or cannot have an orgasm until after prolonged intercourse which might last for 30–45 minutes or more. [1] Delayed ejaculation is closely related to anorgasmia.

Contents

In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition , the definition of DE requires 1 of 2 symptoms: either a marked delay in or a marked infrequency or absence of ejaculation on 75% to 100% of occasions for at least 6 months of partnered sexual activity without the individual desiring delay, and causing significant distress to the individual. DE is meant to describe any and all of the ejaculatory disorders that result in a delay or absence of ejaculation. The Third International Consultation on Sexual Medicine defined DE as an intravaginal ejaculation latency time threshold beyond 20 to 25 minutes of sexual activity, as well as negative personal consequences such as bother or distress. Of note, most men's intravaginal ejaculation latency time range is approximately 4 to 10 minutes. While ejaculatory latency and control were significant criteria to differentiate men with DE from those without ejaculatory disorders, bother/distress did not emerge as a significant factor. [2]

Delayed ejaculation is the least common of the male sexual dysfunctions, and can result as a side effect of some medications. In one survey, 8% of men reported being unable to achieve orgasm over a two-month period or longer in the previous year. [3] DEs are either primary and lifelong or acquired. Acquired DEs may be situational. While most men do experience occasional or short term delayed ejaculation issues, the prevalence of lifelong DE and acquired long-term DE is estimated around 1% and 4%, respectively. [4]

Signs and symptoms

Delayed ejaculation can be mild (men who still experience orgasm during intercourse, but only under certain conditions), moderate (cannot ejaculate during intercourse, but can during fellatio or a handjob), severe (can ejaculate only when alone), or most severe (cannot ejaculate at all). [3] All forms may result in a sense of sexual frustration. [5] In most cases, delayed ejaculation presents the condition in which the man can climax and ejaculate only during masturbation, but not during sexual intercourse. As of 2015, the DSM-V uses the term "delayed ejaculation" instead of older terms such as "inhibited ejaculation", "impotent ejaculation" or "retarded ejaculation". [6] To determine what amount of time counts as delayed, one source uses a measurement of the mean time for a man to achieve ejaculation in a study of 500 couples having heterosexual vaginal intercourse, which was 8 minutes (with a standard deviation of 7.1 minutes). [7] Due to men's reputation for being reliably able to ejaculate during sex, in cases where a man faces delayed ejaculation, the woman may perceive that it is due to her not being attractive or due to a fault in her sexual techniques. [8]

Causes

The etiologies of delayed ejaculation can be age-related, organic, psychological, or pharmacological. [9]

Primary lifelong DEs are poorly understood and rarely explained by few congenital anatomic causes (viz., Müllerian duct cyst, Wolfian duct abnormalities, prune belly syndrome, imperforate anus, congenital ejaculatory duct obstruction, genetic abnormalities including cystic fibrosis, etc.)

Diagnosis

Diagnosis and management of DE warrant one of the most comprehensive medical evaluation in sexual health assessment that includes a full medical and sexual history performed along with a detailed physical examination. Understanding the quality of the sexual response cycle (desire, arousal, ejaculation, orgasm, and refractory period); details of the ejaculatory response, sensation, frequency, and sexual activity/techniques; cultural context and history of the disorder; partner's assessment of the disorder and if the partner has any sexual dysfunction themselves; and the overall satisfaction of the sexual relationship are all important to garner during history-taking. [35]

Relatively normal latency to orgasm with self masturbation as compared to insertive or intravaginal ejaculation latency time reasonably rules out most of the organic causes of DEs.

Treatment

Primary, lifelong DEs are poorly understood and hence less well studied. Organic causes in the acquired DEs should be addresses promptly. Retraining masturbatory practices and re-calibrating the mismatch of sexual fantasies with arousal are essential when these are contributing to DE. Techniques geared towards reduction of anxiety are important skills that can help overcome performance anxiety, as this can often interrupt the natural erectile function through orgasmic progression. [36]

Sex therapy

Therapy usually involves homework assignments and exercises intended to help a man get used to having orgasms through insertional intercourse, vaginal, anal, or oral, that is through the way to which he is not accustomed. Commonly, the couple is advised to go through three stages. [37] At the first stage, a man masturbates in the presence of his partner. Sometimes, this is not an easy matter as a man may be used to having orgasms alone. After a man learns to ejaculate in the presence of his partner, the man's hand is replaced with the hand of his partner. In the final stage, the receptive partner inserts the insertive partner's penis into the partner's vagina, anus, or mouth as soon as the ejaculation is felt to be imminent. Thus, a man gradually learns to ejaculate inside the desired orifice by an incremental process. [3]

Medication

There is as yet no reliable medication for all cases of delayed ejaculation. Some studies have found that PDE5 inhibitors such as Viagra have little effect. [38] Viagra can have a delaying effect on ejaculation, possibly through additional effect in the brain or decrease of sensitivity in the head of the penis. [39]

Cabergoline, an agonist of dopamine D2 receptors which inhibits prolactin production, was found in a small study to fully restore orgasm in one third of anorgasmic subjects, and partially restore orgasm in another third. Limited data has shown that the drug amantadine may help to relieve SSRI-induced orgasmic dysfunction. [40] [41] [42] Cyproheptadine, buspirone, stimulants such as amphetamines (including the antidepressant bupropion), nefazodone has been used to treat SSRI-induced anorgasmia. [43] Reducing the SSRI dosage may also resolve anorgasmia problems. Yohimbine has been shown to be effective in the treatment of orgasmic dysfunction in men. [44]

Other

Meditation has demonstrated effectiveness in case studies. [45]

See also

References

  1. Knowles, David R. (2005-06-01). "Delayed ejaculation". A.D.A.M. Medical Encyclopedia. A.D.A.M., Inc. Retrieved 2007-05-24.
  2. Rowland DL, Cote-Leger P (October 2020). "Moving Toward Empirically Based Standardization in the Diagnosis of Delayed Ejaculation". J Sex Med. 17 (10): 1896–1902. doi:10.1016/j.jsxm.2020.07.017. PMID   32828700.
  3. 1 2 3 4 Strassberg, D.S.; Perelman, M.A. (2009). "Part III Other Axis I Syndromes 15. Sexual Dysfunctions". In Blaney, P.H.; Millon, T. (eds.). Oxford textbook of psychopathology (2nd ed.). Oxford University Press. pp. 399–430. ISBN   978-0-19-970582-5.
  4. Di Sante S, Mollaioli D, Gravina GL, Ciocca G, Limoncin E, Carosa E, Lenzi A, Jannini EA (August 2016). "Epidemiology of delayed ejaculation". Transl Androl Urol. 5 (4): 541–8. doi: 10.21037/tau.2016.05.10 . PMC   5002002 . PMID   27652226.
  5. Hatzimouratidis K, Amar E, Eardley I, Giuliano F, Hatzichristou D, Montorsi F, Vardi Y, Wespes E (May 2010). "Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation". Eur Urol. 57 (5): 804–14. doi:10.1016/j.eururo.2010.02.020. PMID   20189712.
  6. Wincze & Weisberg 2015 , p. 39
  7. Wincze & Weisberg 2015 , p. 40
  8. Strassberg, Mackaronis & Perelman 2014 , p. 444
  9. Abdel-Hamid IA, Ali OI (January 2018). "Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment". World J Mens Health. 36 (1): 22–40. doi:10.5534/wjmh.17051. PMC   5756804 . PMID   29299903.
  10. Dias J, Freitas R, Amorim R, Espiridião P, Xambre L, Ferraz L (June 2014). "Adult circumcision and male sexual health: a retrospective analysis". Andrologia. 46 (5): 459–64. doi:10.1111/and.12101. PMID   23600924.
  11. Bañuelos Marco, Beatriz; García Heil, Jessica Leigh (2021). "Circumcision in childhood and male sexual function: a blessing or a curse?". International Journal of Impotence Research. 33 (2): 139–148. doi:10.1038/s41443-020-00354-y. PMC   7985026 . PMID   32994555.
  12. Gao, Jingjing; Xu, Chuan; Zhang, Xiansheng (2016). "AB221. Effects of adult male circumcision on premature ejaculation: results from a prospective study in China". Translational Andrology and Urology. 5 (Suppl 1): 221. doi: 10.21037/tau.2016.s221 . ISSN   2223-4691. PMC   4842720 .
  13. Kim, Hyuncheol (2016-06-08). "Long-term Effects of Male Circumcision on Risky Sexual Behaviors and STD Infections: Evidence from Malawian Secondary Schools". AEA Randomized Controlled Trials. doi:10.1257/rct.1335-1.0 . Retrieved 2024-01-06.
  14. Warees, Warees M.; Anand, Sachit; Rodriguez, Alexander M. (2023), "Circumcision", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID   30571057 , retrieved 2024-01-06
  15. Sorrells ML, Snyder JL, Reiss MD, Eden C, Milos MF, Wilcox N, Van Howe RS (April 2007). "Fine-touch pressure thresholds in the adult penis". BJU Int. 99 (4): 864–9. doi:10.1111/j.1464-410X.2006.06685.x. PMID   17378847.
  16. Collins, S.; Upshaw, J.; Rutchik, S.; Ohannessian, C.; Ortenberg, J.; Albertsen, P. (2002). "Collins, S., Upshaw, J., Rutchik, S. O., C., Ortenberg, J., & Albertsen, P. (2002). Effects of circumcision on male sexual function: Debunking a myth? J Urol, 167, 2111-2112". J Urol. 167 (5): 2111–2. doi:10.1016/S0022-5347(05)65097-5. PMID   11956452.
  17. Coursey, J. W.; Morey, A. F.; McAninch, J. W.; Summerton, D. J.; Secrest, C.; White, P.; Miller, K.; Pieczonka, C.; Hochberg, D.; Armenakas, N. (2001). "Coursey, J. W., Morey, A. F., McAninch, J. W., Summerton, D. J., Secrest, C.,White, P., et al. (2001). Erectile function after anterior urethroplasty. J Urol, 166 (6), 2273-2276". J Urol. 166 (6): 2273–6. doi:10.1016/S0022-5347(05)65549-8. PMID   11696750.
  18. Ahmady, Kameel Et al 2023: Blade of Tradition in the Name of Religion (A Phenomenological Investigation into Male Circumcision in Iran), Scholar's Press Publishing, Republic of Moldova.
  19. Ongun, Sakir; Dursun, Murat; Egriboyun, Sedat (2020). "The effect of post-circumcision mucosal cuff length on premature ejaculation". Canadian Urological Association Journal. 14 (7): E309 –E312. doi:10.5489/cuaj.6016. ISSN   1911-6470. PMC   7337711 . PMID   32017696.
  20. Gao, Jingjing; Xu, Chuan; Zhang, Jingjing; Liang, Chaozhao; Su, Puyu; Peng, Zhen; Shi, Kai; Tang, Dongdong; Gao, Pan; Lu, Zhaoxiang; Liu, Jishuang; Xia, Lei; Yang, Jiajia; Hao, Zongyao; Zhou, Jun (2015-01-28). "Effects of Adult Male Circumcision on Premature Ejaculation: Results from a Prospective Study in China". BioMed Research International. 2015: e417846. doi: 10.1155/2015/417846 . ISSN   2314-6133. PMC   4324807 . PMID   25695078.
  21. Namavar, Mohammad Reza; Robati, Boroomand (2011). "Removal of foreskin remnants in circumcised adults for treatment of premature ejaculation". Urology Annals. 3 (2): 87–92. doi: 10.4103/0974-7796.82175 . ISSN   0974-7796. PMC   3130485 . PMID   21747599.
  22. Bernaschina-Rivera, Sebastián A.; López-Chaim, Alexandra I.; Cordero-Pacheco, José A.; Fernández-Crespo, Raúl; Quesada-Olarte, José; Carrión, Rafael (October 2023). "Circumcision and Sexual Medicine". Sexual Medicine Reviews. pp. 412–420. doi:10.1093/sxmrev/qead009. PMID   37085961 . Retrieved 2024-01-06.
  23. Morgentaler A, Polzer P, Althof S, Bolyakov A, Donatucci C, Ni X, Patel AB, Basaria S (September 2017). "Delayed Ejaculation and Associated Complaints: Relationship to Ejaculation Times and Serum Testosterone Levels". J Sex Med. 14 (9): 1116–24. doi:10.1016/j.jsxm.2017.06.013. PMID   28807505.
  24. Paduch DA, Polzer P, Morgentaler A, Althof S, Donatucci C, Ni X, Patel AB, Basaria S (December 2015). "Clinical and Demographic Correlates of Ejaculatory Dysfunctions Other Than Premature Ejaculation: A Prospective, Observational Study". J Sex Med. 12 (12): 2276–86. doi:10.1111/jsm.13027. PMID   26511106.
  25. drugs.com Delayed ejaculation Archived 2019-02-20 at the Wayback Machine Review Date: 6/5/2007. Reviewed By: Marc Greenstein, DO, Urologist, North Jersey Center for Urologic Care
  26. Smith, Shubulade; Robin Murray; Veronica O'Keane (2002). "Sexual dysfunction in patients taking conventional antipsychotic medication". The British Journal of Psychiatry. 181: 49–55. doi: 10.1192/bjp.181.1.49 . PMID   12091263.
  27. Ghadigaonkar, Deepak S.; Murthy, Pratima (2019). "Sexual Dysfunction in Persons with Substance Use Disorders". Journal of Psychosexual Health. 1 (2): 117–121. doi: 10.1177/2631831819849365 . S2CID   196538029.
  28. Mann, Jay (1976). "Retarded ejaculation and treatment". International Congress of Sexology.
  29. 1 2 3 Wincze & Weisberg 2015 , p. 42
  30. Bronner, Gila; Ben-Zion, Itzhak Z. (July 2014). "Unusual Masturbatory Practice as an Etiological Factor in the Diagnosis and Treatment of Sexual Dysfunction in Young Men". The Journal of Sexual Medicine. 11 (7): 1798–1806. doi:10.1111/jsm.12501. PMID   24674621 . Retrieved 31 October 2024.
  31. Althof SE (2012). "Psychological interventions for delayed ejaculation/orgasm". Int J Impot Res. 24 (4): 131–6. doi:10.1038/ijir.2012.2. PMID   22378496.
  32. Sank, Lawrence (1998). "Traumatic masturbatory syndrome". Journal of Sex & Marital Therapy. 24 (1): 37–42. doi:10.1080/00926239808414667. PMID   9509379.
  33. Perelman MA, Rowland DL (December 2006). "Retarded ejaculation". World J Urol. 24 (6): 645–52. doi:10.1007/s00345-006-0127-6. PMID   17082938.
  34. American Psychiatric Association (2022). "Sexual Dysfunctions". Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR(tm)). G - Reference,Information and Interdisciplinary Subjects Series. American Psychiatric Association Publishing. p. 479. ISBN   978-0-89042-576-3.
  35. Rowland D, McMahon CG, Abdo C, Chen J, Jannini E, Waldinger MD, Ahn TY (April 2010). "Disorders of orgasm and ejaculation in men". J Sex Med. 7 (4 Pt 2): 1668–86. doi:10.1111/j.1743-6109.2010.01782.x. PMID   20388164.
  36. "INTRODUCTION - Uroweb". Uroweb - European Association of Urology. Retrieved 2024-05-23.
  37. Dr. David Delvin (2007-06-25). "Delayed ejaculation (retarded ejaculation)". Netdoctor. NetDoctor.co.uk. Archived from the original on 2015-10-21. Retrieved 2007-10-25.
  38. The Carlat Psychiatry Report > PDE-5 Inhibitors: Which to Choose? Archived 2019-12-16 at the Wayback Machine Published in The Carlat Psychiatry Report. December 2004, Volume 2, Number 12
  39. WebMD Health News > Viagra, Paxil Help Premature Ejaculation. May 29, 2002. By Martin F. Downs.
  40. Shrivastava RK, Shrivastava S, Overweg N, Schmitt M (1995). "Amantadine in the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors". Journal of Clinical Psychopharmacology . 15 (1): 83–84. doi:10.1097/00004714-199502000-00014. PMID   7714234.
  41. Balogh S, Hendricks SE, Kang J (1992). "Treatment of fluoxetine-induced anorgasmia with amantadine". The Journal of Clinical Psychiatry . 53 (6): 212–13. PMID   1607353.
  42. Keller Ashton A, Hamer R, Rosen RC (1997). "Serotonin reuptake inhibitor-induced sexual dysfunction and its treatment: a large-scale retrospective study of 596 psychiatric outpatients". Journal of Sex & Marital Therapy . 23 (3): 165–75. doi:10.1080/00926239708403922. PMID   9292832.
  43. Gitlin, Michael J. (1998). "Treatment of Antidepressant-Induced Sexual Dysfunction". Medscape Psychiatry & Mental Health eJournal. 3 (3). Retrieved 4 April 2018.
  44. Adeniyi AA, Brindley GS, Pryor JP, Ralph DJ (May 2007). "Yohimbine in the treatment of orgasmic dysfunction". Asian Journal of Andrology. 9 (3): 403–07. doi: 10.1111/J.1745-7262.2007.00276.x . PMID   17486282.
  45. M. M. Delmonte (June 1984). "Case reports on the use of meditative relaxation as an intervention strategy with retarded ejaculation". Biofeedback and Self-Regulation. 9 (2): 209–214. doi:10.1007/BF00998835. PMID   6391563. S2CID   40959207.

Bibliography