This is a list of administrative divisions of Ukraine sorted by their gross regional domestic product (GRPD). GRPD is the regional counterpart of the national gross regional domestic product (GDP), the most comprehensive measure of national economic activity.
Crimea and Sevastopol are excluded because they have no data and are fully controlled by Russia.
| Rank | Region | 2021 |
|---|---|---|
| 1 |  Kyiv | 33.1 |
| 2 |  Dnipropetrovsk Oblast | 15.1 |
| 3 |  Kharkiv Oblast | 8.3 |
| 4 |  Lviv Oblast | 7.7 |
| 5 |  Kyiv Oblast | 7.6 |
| 6 |  Donetsk Oblast | 7.3 |
| 7 |  Odesa Oblast | 7.0 |
| 8 |  Poltava Oblast | 6.9 |
| 9 |  Zaporizhzhia Oblast | 5.9 |
| 10 |  Vinnytsia Oblast | 4.5 |
| 11 |  Cherkasy Oblast | 3.4 |
| 12 |  Mykolaiv Oblast | 3.2 |
| 13 |  Khmelnytskyi Oblast | 3.1 |
| 14 |  Ivano-Frankivsk Oblast | 3.1 |
| 15 |  Zhytomyr Oblast | 3.0 |
| 16 |  Chernihiv Oblast | 2.9 |
| 17 |  Sumy Oblast | 2.7 |
| 18 |  Kirovohrad Oblast | 2.6 |
| 19 |  Volyn Oblast | 2.4 |
| 20 |  Rivne Oblast | 2.3 |
| 21 |  Kherson Oblast | 2.3 |
| 22 |  Ternopil Oblast | 2.1 |
| 23 |  Zakarpattia Oblast | 2.0 |
| 24 |  Chernivtsi Oblast | 1.4 |
| 25 |  Luhansk Oblast | 1.4 |
| — | Ukraine | 141.3 |