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Other names | Testosterone 17β-trimethylsilyl ether; Testosterone O-trimethylsilyl ether; 17β-Trimethylsilyltestosterone; O-Trimethylsilyltestosterone; 17β-(trimethylsiloxy)androst-4-en-3-one; SC-16148; NSC-95147 |
Routes of administration | By mouth, intramuscular injection, subcutaneous injection |
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ECHA InfoCard | 100.023.414 |
Chemical and physical data | |
Formula | C22H36O2Si |
Molar mass | 360.613 g·mol−1 |
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Silandrone (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name) (developmental code name SC-16148), also known as testosterone 17β-trimethylsilyl ether or 17β-trimethylsilyltestosterone, as well as 17β-(trimethylsiloxy)androst-4-en-3-one, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ether – specifically, the 17β-trimethylsilyl ether of testosterone – which was developed by the G. D. Searle & Company in the 1960s but was never marketed. [1] It has a very long duration of action when given via subcutaneous or intramuscular injection, as well as significantly greater potency than that of testosterone propionate. [2] [3] In addition, silandrone, unlike testosterone and most esters of testosterone like testosterone propionate, is orally active. [4]
Testosterone cypionate, sold under the brand name Depo-Testosterone among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It is also used in hormone therapy for transgender men. It is given by injection into muscle or subcutaneously, once every one to four weeks, depending on clinical indication.
Testosterone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It is also used in hormone therapy for transgender men. It is given by injection into muscle or subcutaneously usually once every one to four weeks.
Testosterone propionate, sold under the brand name Testoviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It has also been used to treat breast cancer in women. It is given by injection into muscle usually once every two to three days.
Drostanolone propionate, or dromostanolone propionate, sold under the brand names Drolban, Masteril, and Masteron among others, is an androgen and anabolic steroid (AAS) medication which was used to treat breast cancer in women but is now no longer marketed. It is given by injection into muscle.
Methandriol, also known as methylandrostenediol, is an androgen and anabolic steroid (AAS) medication which was developed by Organon and is used in both oral and injectable formulations. It is an orally active 17α-alkylated AAS and a derivative of the endogenous androgen prohormone androstenediol.
Propetandrol, or propethandrol, also known as 17α-ethyl-19-nortestosterone 3β-propionate or 17α-ethyl-19-nor-4-androstenediol 3β-propionate, as well as 17α-ethylestr-4-en-3β,17β-diol 3β-propionate, is a synthetic and orally active anabolic–androgenic steroid (AAS) and progestogen and a 17α-alkylated derivative of 19-nortestosterone. It is an androgen ester – specifically, the 3β-propionate ester of norethandrolone (17α-ethyl-19-nortestosterone).
Cloxotestosterone, also known as 17β-chloral hemiacetal testosterone, is a synthetic anabolic–androgenic steroid (AAS) and an androgen ether – specifically, the 17β-trichloro hemiacetal ether of testosterone – which was never marketed. The O-acetate ester of cloxotestosterone, cloxotestosterone acetate, in contrast to cloxotestosterone, has been marketed.
Orestrate, also known as estradiol 3-propionate 17β-(1-cyclohexenyl) ether, is an estrogen medication and estrogen ester which was never marketed. It is the C3 propionate ester and C17β-(1-cyclohexenyl) ether of estradiol.
Cloxotestosterone acetate, also known as testosterone 17β-chloral hemiacetal O-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ether and ester – specifically, the O-acetate ester of cloxotestosterone, the 17β-trichloro hemiacetal ether of testosterone. It is administered via intramuscular injection, as a 100 mg, 2 mL aqueous suspension and lasts 4 to 6 weeks with a single administration. The drug was first marketed in the early 1960s.
Bolandiol dipropionate (USAN), or bolandiol propionate (JAN), also known as norpropandrolate or 19-nor-4-androstenediol dipropionate, as well as estr-4-ene-3β,17β-diol 3,17-dipropionate, is a synthetic anabolic-androgenic steroid (AAS) and derivative of 19-nortestosterone (nandrolone). It is an androgen ester – specifically, the 3,17-dipropionate ester of bolandiol (19-nor-4-androstenediol).
Boldenone undecylenate, or boldenone undecenoate, sold under the brand names Equipoise and Parenabol among others, is an androgen and anabolic steroid (AAS) medication which is used in veterinary medicine, mainly in horses. It was formerly used in humans as well. It is given by injection into muscle.
Clostebol acetate (BAN), also known as 4-chlorotestosterone 17β-acetate (4-CLTA) or as 4-chloroandrost-4-en-17β-ol-3-one 17β-acetate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone that is marketed in Germany and Italy. It is an androgen ester – specifically, the C17β acetate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection.
Clostebol caproate, also known as clostebol hexanoate or chlorotestosterone caproate (JAN), as well as 4-chlorotestosterone 17β-caproate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-caproate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an androgen ester – specifically, the C17β caproate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection.
Clostebol propionate, also known as 4-chlorotestosterone 17β-propionate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-propionate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an androgen ester – specifically, the C17β propionate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection.
Testosterone valerate, or testosterone pentanoate, also known as androst-4-en-17β-ol-3-one 17β-valerate, is a synthetic, steroidal androgen and an androgen ester – specifically, the C17β valerate ester of testosterone – which is used in veterinary medicine. It is administered via intramuscular injection and acts as a long-lasting prodrug of testosterone. The medication is available as a component of the veterinary drug Deposterona, which is marketed in Mexico and also contains testosterone acetate and testosterone undecanoate. Testosterone valerate is a short-to-medium duration ester of testosterone, with an elimination half-life of approximately twice that of the short-acting testosterone propionate.
Testosterone butyrate, or testosterone butanoate, also known as androst-4-en-17β-ol-3-one 17β-butanoate, is a synthetic, steroidal androgen and an androgen ester – specifically, the C17β butanoate ester of testosterone – which was first synthesized in the 1930s and was never marketed. Its ester side-chain length and duration of effect are intermediate between those of testosterone propionate and testosterone valerate.
Testosterone benzoate, or testosterone 17β-benzoate, also known as androst-4-en-17β-ol-3-one 17β-benzoate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ester – specifically, the benzoate C17β ester of testosterone – which was never marketed. It is a prodrug of testosterone and, when administered via intramuscular injection, is associated with a long-lasting depot effect and extended duration of action. The drug was first described in 1936 and was the first androgen ester and ester of testosterone to be synthesized.
Testosterone acetate propionate, or testosterone 3β-acetate 17β-propanoate, also known as 4-androstenediol acetate propionate, as well as androst-4-ene-3β,17β-diol 3β-acetate 17β-propanoate, is a synthetic anabolic-androgenic steroid and an androgen ester which was never marketed. It is the 3β-acetate, 17β-propionate (propanoate) diester of testosterone (androst-4-en-17β-ol-3-one), or, more accurately, of 4-androstenediol (androst-4-ene-3β,17β-diol).