Bolazine capronate

Bolazine capronate
Clinical data
Trade names	Roxilon Inject
Other names	Bolazine caproate; Bolazine hexanoate; Di(drostanolone capronate) azine; 2α-Methyl-5α-androstan-17β-ol-3-one 17β-hexanoate azine
Routes of; administration	Intramuscular injection
Identifiers
	IUPAC name (1S,2S,4R,5Z,7S,10R,11S,14S,15S)-5-{2-[(1S,2S,4R,5E,7S,10R,11S,14S,15S)-14-(hexanoyloxy)-2,4,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-ylidene]hydrazin-1-ylidene}-2,4,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl hexanoate;
ChemSpider	8254591 ;
Chemical and physical data
Formula	C52H84N2O4
Molar mass	801.254 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES CCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C\C(=N\N=C5/C[C@@H]6CC[C@H]7[C@@H]8CC[C@H](OC(=O)CCCCC)[C@@]8(C)CC[C@@H]7[C@@]6(C)C[C@H]5C)[C@H](C)C[C@]4(C)[C@H]3CC[C@]12C;
	InChI InChI=1S/C52H84N2O4/c1-9-11-13-15-47(55)57-45-23-21-39-37-19-17-35-29-43(33(3)31-51(35,7)41(37)25-27-49(39,45)5)53-54-44-30-36-18-20-38-40-22-24-46(58-48(56)16-14-12-10-2)50(40,6)28-26-42(38)52(36,8)32-34(44)4/h33-42,45-46H,9-32H2,1-8H3/b53-43-,54-44+/t33-,34-,35+,36+,37+,38+,39+,40+,41+,42+,45+,46+,49?,50+,51?,52+/m1/s1; Key:AOAFJVPZPNBTQX-VNBRUOELSA-N;

Last updated December 09, 2023

Bolazine capronate (INN Tooltip International Nonproprietary Name)^{[ additional citation(s) needed ]} (brand name Roxilon Inject), also known as bolazine caproate or bolazine hexanoate, as well as di(drostanolone capronate) azine or 2α-methyl-5α-androstan-17β-ol-3-one 17β-hexanoate azine, is a synthetic, injected androgen/anabolic steroid (AAS), and derivative of dihydrotestosterone (DHT).^[1]^[2] It is an androgen ester – specifically, the C17β hexanoate ester of bolazine.^[1]^[2]

Related Research Articles

Metenolone enanthate, or methenolone enanthate, sold under the brand names Primobolan Depot and Nibal Injection, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. It is given by injection into muscle. Although it was widely used in the past, the drug has mostly been discontinued and hence is now mostly only available on the black market. A related drug, metenolone acetate, is taken by mouth.

Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of trestolone. The medication was first described in 1963.

<span class="mw-page-title-main">Bolazine</span> Chemical compound

Bolazine, also known as 2α-methyl-5α-androstan-17β-ol-3-one azine, is a synthetic androgen/anabolic steroid (AAS) of the dihydrotestosterone (DHT) group which was never marketed. It is not orally active and is used as the ester prodrug bolazine capronate via depot intramuscular injection. Bolazine has a unique and unusual chemical structure, being a dimer of drostanolone linked at the C3 position of the A-ring by an azine group, and reportedly acts as a prodrug of drostanolone.

<span class="mw-page-title-main">Mebolazine</span> Chemical compound

Mebolazine is a synthetic, orally active androgen/anabolic steroid (AAS) and a 17α-alkylated derivative of dihydrotestosterone (DHT) which is no longer marketed. It has a unique and unusual chemical structure, being a dimer of methasterone linked at the 3-position of the A-ring by an azine group, and reportedly acts as a prodrug of methasterone.

Cloxotestosterone acetate, also known as testosterone 17β-chloral hemiacetal O-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ether and ester – specifically, the O-acetate ester of cloxotestosterone, the 17β-trichloro hemiacetal ether of testosterone. It is administered via intramuscular injection, as a 100 mg, 2 mL aqueous suspension and lasts 4 to 6 weeks with a single administration. The drug was first marketed in the early 1960s.

Androstanolone benzoate, also known as stanolone benzoate or dihydrotestosterone benzoate (DHTB), as well as 5α-androstan-17β-ol-3-one 17β-benzoate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester. It is used as an injectable and acts as a prodrug of androstanolone.

Androstanolone enanthate, also known as stanolone enanthate or dihydrotestosterone heptanoate (DHTH), as well as 5α-androstan-17β-ol-3-one 17β-heptanoate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester. It is used as an injectable and acts as a prodrug of androstanolone. The drug has been studied in and found to be effective in the treatment of gynecomastia in boys and adult men. The pharmacology of androstanolone enanthate has been studied.

Androstanolone propionate, also known as stanolone propionate or dihydrotestosterone propionate (DHTP), as well as 5α-androstan-17β-ol-3-one 17β-propionate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that is marketed in Italy. It is used as an injectable and acts as a prodrug of androstanolone.

Androstanolone valerate, also known as stanolone valerate or dihydrotestosterone pentanoate, as well as 5α-androstan-17β-3-one 17β-valerate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester. It is used as an injectable and acts as a prodrug of androstanolone.

Dihydrotestosterone acetate, also known as androstanolone acetate or stanolone acetate, as well as 5α-dihydrotestosterone 17β-acetate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.

Dihydrotestosterone butyrate, also known as androstanolone butyrate or stanolone butyrate, as well as 5α-dihydrotestosterone 17β-butanoate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.

Dihydrotestosterone formate, also known as androstanolone formate or stanolone formate, as well as 5α-dihydrotestosterone 17β-formate, is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.

Nandrolone caproate, or nandrolone hexanoate, also known as 19-nortestosterone 17β-hexanoate, is a synthetic androgen and anabolic steroid and a nandrolone ester.

Norclostebol acetate, or norchlorotestosterone acetate (NClTA), also known as 4-chloro-19-nortestosterone 17β-acetate or as 4-chloroestr-4-en-17β-ol-3-one, is a synthetic, injectable anabolic-androgenic steroid (AAS) and derivative of 19-nortestosterone (nandrolone). It is an androgen ester – specifically, the C17β acetate ester of norclostebol (4-chloro-19-nortestosterone).

Boldenone undecylenate, or boldenone undecenoate, sold under the brand names Equipoise and Parenabol among others, is an androgen and anabolic steroid (AAS) medication which is used in veterinary medicine, mainly in horses. It was formerly used in humans as well. It is given by injection into muscle.

Stenbolone acetate, also known as 2-methyl-4,5α-dihydro-δ¹-testosterone 17β-acetate or as 2-methyl-5α-androst-1-en-17β-ol-3-one 17β-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT) which has been marketed in Spain.

Metenolone acetate, or methenolone acetate, sold under the brand names Primobolan and Nibal, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. It is taken by mouth. Although it was widely used in the past, the drug has mostly been discontinued and hence is now mostly no longer available. A related drug, metenolone enanthate, is given by injection into muscle.

Clostebol caproate, also known as clostebol hexanoate or chlorotestosterone caproate (JAN), as well as 4-chlorotestosterone 17β-caproate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-caproate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an androgen ester – specifically, the C17β caproate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection.

Nisterime acetate (USAN) (developmental code name ORF-9326), also known as 2α-chloro-4,5α-dihydrotestosterone O-(p-nitrophenyl)oxime 17β-acetate or as 2α-chloro-5α-androstan-17β-ol-3-one O-(p-nitrophenyl)oxime 17β-acetate, is a synthetic, orally active anabolic-androgenic steroid (AAS) and a derivative of dihydrotestosterone (DHT) that was developed as a postcoital contraceptive but was never marketed. It is an androgen ester – specifically, the C17α acetate ester of nisterime. Unlike antiprogestogens like mifepristone, nisterime acetate does not prevent implantation and instead induces embryo resorption as well as interrupts the post-implantation stage of pregnancy.

References

1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 653–. ISBN 978-1-4757-2085-3.
1 2 García-Manso JM, Valverde Esteve T (2016). Consequences of the Use of Anabolic-Androgenic Steroids on Female Athletes' Fertility. Springer. pp. 229–238. doi:10.1007/978-1-4939-3402-7_14. ISBN 978-1-4939-3400-3.

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[Elks2014-1] 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 653–. ISBN 978-1-4757-2085-3.

[García-MansoValverde_Esteve2016-2] 1 2 García-Manso JM, Valverde Esteve T (2016). Consequences of the Use of Anabolic-Androgenic Steroids on Female Athletes' Fertility. Springer. pp. 229–238. doi:10.1007/978-1-4939-3402-7_14. ISBN 978-1-4939-3400-3.

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Bolazine capronate

See also

Related Research Articles

References