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| Clinical data | |
|---|---|
| Trade names | Bebate; Benisone |
| Other names | Betamethasone 17-benzoate |
| Drug class | Corticosteroid; Glucocorticoid |
| Identifiers | |
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| CAS Number | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.040.801  |
| Chemical and physical data | |
| Formula | C29H33FO6 |
| Molar mass | 496.575 g·mol−1 |
| 3D model (JSmol) | |
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Betamethasone benzoate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Optic neuritis is a demyelinating inflammation of the optic nerve. It is also known as optic papillitis, neuroretinitis when there is a combined involvement of optic disc and surrounding retina in the macular area and retrobulbar neuritis. It is most often associated with multiple sclerosis, and it may lead to complete or partial loss of vision in one or both eyes. Other causes include:
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.
Cortisone is a pregnane (21-carbon) steroid hormone. It is one of the main hormones released by the adrenal gland in response to stress. In chemical structure, it is a corticosteroid closely related to cortisol. It is used to treat a variety of ailments and can be administered intravenously, orally, intra-articularly, or transcutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.
Sore throat, also known as throat pain, is pain or irritation of the throat. It is usually caused by pharyngitis or tonsillitis. It can also result from trauma.
Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals. In humans it is encoded by the SERPINA6 gene. It is an alpha-globulin.
Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids. It is taken by mouth.
Methylprednisolone, sold under the brand name Depo-Medrol among others, is a corticosteroid medication used to suppress the immune system and decrease inflammation. Conditions in which it is used include skin diseases, rheumatic disorders, allergies, asthma, croup, COPD, certain cancers, multiple sclerosis, and as add-on therapy for tuberculosis. It is given by mouth, by injection into a vein or muscle, or applied to the skin.
Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. Other trade names for creams, lotions, and ointments include Tridesilon, DesOwen, Desonate. It is a group VI corticosteroid under US classification, the second least potent group.
Fluticasone propionate, sold under the brand names Flovent and Flonase among others, is a steroid medication. When inhaled it is used for the long term management of asthma and COPD. In the nose it is used for hay fever and nasal polyps. It can also be used for mouth ulcers.
Minimal change disease is a disease affecting the kidneys which causes a nephrotic syndrome. Nephrotic syndrome leads to the loss of significant amounts of protein in the urine, which causes the widespread oedema and impaired kidney function commonly experienced by those affected by the disease. It is most common in children and has a peak incidence at 2 to 6 years of age. MCD is responsible for 10-25% of nephrotic syndrome cases in adults. It is also the most common cause of nephrotic syndrome of unclear cause (idiopathic) in children.
Triamcinolone diacetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Flunisolide is a corticosteroid often prescribed as treatment for allergic rhinitis. Intranasal corticosteroids are the most effective medication for controlling symptoms.
Alclometasone dipropionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Tixocortol is a corticosteroid used as an intestinal anti-inflammatory and decongestant.
Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly. Corticosteroids have always been an important part of the pharmacological arsenal of dermatology; however, their tendency to produce side-effects has caused the need to search for new preparations.
Clobetasone butyrate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Fluprednisolone is a pregnane. It is a corticosteroid.
Paramethasone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the acetate ester of paramethasone.
Flumetasone pivalate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of flumetasone.
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