Misuse of Drugs Act 1971

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Misuse of Drugs Act 1971 [1]
Act of Parliament
Coat of arms of the United Kingdom (2022, variant 1).svg
Long title An Act to make new provision with respect to dangerous or otherwise harmful drugs and related matters, and for purposes connected therewith.
Citation 1971 c. 38
Introduced by Reginald Maudling
Territorial extent England and Wales; Scotland; Northern Ireland
Dates
Royal assent 27 May 1971
Status: Amended
Text of statute as originally enacted
Revised text of statute as amended

The Misuse of Drugs Act 1971 [1] (c. 38) is an act of the Parliament of the United Kingdom. It represents action in line with treaty commitments under the Single Convention on Narcotic Drugs, [2] the Convention on Psychotropic Substances, [3] and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. [4]

Contents

Offences under the act include: [5]

The act establishes the Home Secretary as the principal authority in a drug licensing system. Therefore, for example, various opiates are available legally as prescription-only medicines, and cannabis (hemp) [6] may be grown under licence for 'industrial purposes'. The Misuse of Drugs Regulations 2001 (SI 2001/3998), [7] created under the 1971 Act, are about licensing of production, possession and supply of substances classified under the act.

The act creates three classes of controlled substances, A, B, and C, and ranges of penalties for illegal or unlicensed possession and possession with intent to supply are graded differently within each class. The lists of substances within each class can be amended by Order in Council, so the Home Secretary can list new drugs and upgrade, downgrade or delist previously controlled drugs with less of the bureaucracy and delay associated with passing an act through both Houses of Parliament.

Critics of the act such as David Nutt say that its classification is not based on how harmful or addictive the substances are, and that it is unscientific to omit substances like tobacco and alcohol.

Provisions

Section 37 Interpretation

Section 37(5) became spent on the repeal of sections 8 to 10 of the Pharmacy and Poisons Act 1933. [8] It was repealed by Group 7 of Part 17 of Schedule 1 to the Statute Law (Repeals) Act 2004.

List of controlled drugs

These drugs are known in the UK as controlled drug, because this is the term by which the act itself refers to them. In more general terms, however, many of these drugs are also controlled by the Medicines Act 1968, there are many other drugs which are controlled by the Medicines Act but not by the Misuse of Drugs Act, and some other drugs (alcohol, for example) are controlled by other laws.

The act sets out four separate categories: Class A, Class B, Class C and temporary class drugs. Substances may be removed and added to different parts of the schedule by statutory instrument, provided a report of the Advisory Council on the Misuse of Drugs has been commissioned and has reached a conclusion, although the Secretary of State is not bound by the council's findings.

In reality the potential harm has little bearing on the class, [9] which has led to dissatisfaction with drug laws. [10]

Substances may be removed and added to different parts of the schedule by statutory instrument, provided a report of the Advisory Council on the Misuse of Drugs has been commissioned and has reached a conclusion, although the Secretary of State is not bound by the council's findings. This list has in practice been modified a great number of times, sometimes removing substances, but more commonly adding some; for example, many benzodiazepines became Class C drugs in 1985, and many cathinones became Class B drugs in 2010.

Glossary of terminology used in this list

anabolic steroids – hormones that build muscle tissue
benzodiazepines – a class of sedative/anxiolytic drugs
cannabinoids – drugs that bind to cannabinoid receptors
arylcyclohexamines – dissociatives which act on the NMDA receptors
opioids – Drugs that bind to opioid receptors
phenethylamines – psychedelics based on phenethylamine
sedatives – drugs that lower arousal
stimulants – drugs that heighten arousal
tryptamines – psychedelics based on tryptamine

Class A drugs

1. The following substances, namely:— [11] [ non-primary source needed ]

Name as specified
in the Act
Brand or
street name
Drug typeYear
added
Notes and comments
Acetorphine opioid1971primarily used to sedate elephants, giraffes and rhinos
Alfentanil 1984
Allylprodine 1971
Alphacetylmethadol synthetic
Alphameprodine
Alphamethadol
Alphaprodine
Anileridine
Benzethidine
Benzylmorphine
Betacetylmethadol
Betameprodine
Betamethadol
Betaprodine
Bezitramide Burgodin
Bufotenin Toad skin toxintryptaminefound in the skins of psychoactive toads, especially Bufo alvarius
Carfentanil Wildnilopioid1986Strongest known opioid; 10,000 times more potent than morphine, 100 times more potent than fentanyl. Used as a tranquilliser for large game (elephants etc.).
Clonitazene 1971
Coca leaf Erythroxylum the plant from which cocaine is derived
Cocaine Coke, Crack, Rock, Girl, Charlie, Sniff, Snow, Packet, Blow, Whiff, Gear, Bugle, Toot, Bag, The Devil's Dandruff, Marching PowderTropane alkaloid
Desomorphine Krokodil (Russian for crocodile)opioidPrimarily used in Russia and Ukraine. Its full chemical name is dihydrodesoxymorphine, and is a 3,6 diester salt of morphine
Dextromoramide Palfium
Diampromide
Diethylthiambutene
Difenoxin Roskies1975
Dihydrocodeinone O-carboxymethyloxime 1971
Dihydroetorphine opioid (see notes)2003Semi-synthetic opioid; derivative of etorphine [12]
Dihydromorphine Paramorphanopioid1971
Dimenoxadol
Dimepheptanol an analogue of methadone
Dimethylthiambutene
Dioxaphetyl butyrate
Diphenoxylate
Dipipanone
Drotebanol 1973
Ecgonine precursor 1971"and any derivative of ecgonine which is convertible to ecgonine or to cocaine"
Ethylmethylthiambutene opioid
Eticyclidine arylcyclohexylamine1984
Etonitazene opioid1971
Etorphine 1,000–3,000 times more potent than morphine, veterinary use only for large game
Etoxeridine
Etryptamine Tryptamine1998 [13]
Fentanyl Actiq, Duragesic, Sublimazeopioid1971Approximately 100 times the strength of morphine
Furethidine
Hydrocodone Vicodin, Norco, Lortab
Hydromorphinol
Hydromorphone Dilaudid, Palladone, Hymorphan, drug store heroin
Hydroxypethidine
Isomethadone Simple positional isomer of Methadone
Ketobemidone
Levomethorphan
Levomoramide the totally inactive isomer of dextromoramide
Levophenacylmorphan
Levorphanol Levo-Dromoran
Lofentanil 1986
Lysergamide ergoline1971a precursor to LSD
Lysergic acid diethylamide LSD, acid"Lysergide and other N-alkyl derivatives of lysergamide"
Mescaline Mescalphenethylaminefound naturally in types of cactus; cacti themselves not illegal
MDMA MD, Ecstasy (abbreviated E, X, or XTC), Molly (US), or Mandy (UK)1977not specifically named but covered by the ban of alkylenedioxy-substituted phenethylamines
MDA not specifically named but covered by the ban of alkylenedioxy-substituted phenethylamines
Metazocine opioid1971
Methadone Methadose, Dolophineused in opioid replacement therapy to treat addiction
Methadyl acetate used in treating opioid addiction, structurally related to methadone
Methamphetamine Desoxyn, Crystal Meth, Meth, Ice, Glass, Tina, Crank, Gak, and othersstimulant2006moved from class B to class A in 2006 [14]
Methyldesorphine opioid1971
Methyldihydromorphine
Metopon
Morphine MS, Dope, Hard Stuff, Miss Emma, Junk, Mister Blue, God's drug, DreamerDerivative of the opium poppy and powerful narcotic painkiller
Morphine diacetate H, Heroin, Smack, Dope, Boy, Junk, Black Tar, Skag, Hero3,6 diester salt of morphine, Morphine prodrug
Morphine methobromide "morphine N-oxide and other pentavalent nitrogen morphine derivatives"
Myrophine
Nicomorphine 3,6 diester salt of morphine
Noracymethadol
Norlevorphanol
Normethadone
Normorphine
Norpipanone Hexalgonmethadol
Opium Laudanum, Pantoponopioid mixturemilky secretion of the opium poppy – banned "whether raw, prepared or medicinal"
Oxycodone OxyContin, PercocetopioidWidely used strong pain killer
Oxymorphone Numorphan, Opana
Pethidine Meperidine, Demerol, Dolantine
Phenadoxone
Phenampromide
Phenazocine Discontinued in 2001
Phencyclidine Angel Dust, PCParylcyclohexylamine1979
Phenomorphan opioid1971
Phenoperidine
Piminodine
Piritramide Dipidolor
Poppy-straw Papaver somniferum "Poppy-straw and concentrate of poppy-straw."
Proheptazine opioid
Properidine
Psilocin TryptaminePsychoactive ingredient found in most psychedelic mushrooms; includes the prodrug psilocybin.
Psilocybin mushroom Magic Mushrooms, Shroomsfungi2005"Fungus (of any kind) that contains psilocin or an ester of psilocin." [15]
Racemethorphan opioid mixture1971 Racemic mixture of Dextromethorphan (DXM) and Levomethorphan
Racemoramide
Racemorphan
Remifentanil opioid2003 [12] Strong painkiller; cannot be used without plasma infusion equipment
Rolicyclidine PCPyarylcyclohexylamine1984Very similar to phencyclidine (PCP)
Sufentanil Sufentaopioid1983
Tenocyclidine TCParylcyclohexylamine1984Very similar to phencyclidine (PCP), but considerably more potent
Tapentadol Nucyntaopioid2009Dual action as a norepinephrine reuptake inhibitor
Thebacon Acedicone1971
Thebaine
Tilidate Valtran1983
Trimeperidine 1971
2,5-Dimethoxy-4-bromoamphetamine DOBphenethylamine1975a drug of the DOx family
4-Cyano-2-dimethylamino-4,4-diphenylbutane opioid (see note)1971Methadone intermediate
4-Cyano-1-methyl-4-phenyl-piperidine Intermediate chemical in generation of the opioid, Pethidine
N,N-Diethyltryptamine DET, T-9tryptamine
N,N-Dimethyltryptamine DMT, ChangaIntense psychedelic drug
2,5-Dimethoxy-4-methylamphetamine DOMphenethylaminea drug of the DOx family.
N-Hydroxy-tenamphetamine MDOHstimulant1990
1-Methyl-4-phenylpiperidine-4-carboxylic acid Pethidinic acid precursor 1971
2-Methyl-3-morpholino-1,1-diphenylpropanecarboxylic acid opioid (see notes)Converted in the body into the opioid Moramide
4-Methyl-aminorex Icestimulant1990
4-Methyl-5-(4-methylphenyl)-4,5-dihydrooxazol-2-amine Serotoni, 4,4'-DMAR2015 [16] [17]
1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine MT-45opioid
4-Phenylpiperidine-4-carboxylic acid ethyl ester Norpethidineopioid (see notes)1971Commonly used in the production of Pethidine, although it has little opioid activity in its own right
N.B. Sub-paragraphs (b) and (c) were added in 1977 [18] , sub-paragraphs (d) and (e) were added in 1986. Sub-paragraph (ba) was subsequently added in 2001. [19]

(b) any compound structurally derived from tryptamine or from a ring-hydroxy tryptamine by modification.

(ba) a number of phenethylamine derivatives. [20] [21]

(c) compounds structurally derived from phenethylamine an N-alkylphenethylamine, a methylphenethylamine, an N-alkyl-α-methylphenethylamine, an ethylphenethylamine, or an N-alkyl-α-ethylphenethylamine by certain modifications.

(d) compounds structurally derived from fentanyl by certain modifications.

(e) compounds structurally derived from pethidine by certain modifications.

(ea) any compound with a maximum molecular mass of 500 atomic mass units and structurally derived from 2-(2-benzyl-benzimidazol-1-yl)ethanamine.

(f) any compound structurally derived from mescaline, 4-bromo-2,5-dimethoxy-α-methylphenethylamine, 2,5-dimethoxy-α,4-dimethylphenethylamine, N-hydroxytenamphetamine (N-hydroxy-MDA), or a compound specified in sub-paragraph (ba) or (c) above, by substitution at the nitrogen atom of the amino group with a benzyl substituent, whether or not substituted in the phenyl ring of the benzyl group to any extent.

2. Any stereoisomeric of a class A substance, exluding dextromethorphan or dextrorphan.

3. Any ester or ether of a class A substance (that is not listed as a class B substance).

4. Any salt of a class A substance.

5. Any preparation or other product containing a class A substance

6. Any preparation of a class B substance designed for administration by injection.

Class B drugs

1. The following substances, namely:— [11] [ non-primary source needed ]

(a)

Name as specified
in the Act
Brand or
street name
Drug type
Year
added
Notes and comments
Acetyldihydrocodeine opioid1971
Amphetamine Adderall, Speed, whizzstimulant
Codeine Purple drank, Lean, Wockopioidlegal without prescription in quantities of up to 12.8 mg per dosage unit or 15 mg/5 ml in oral solution and only in combination with other drug. UK Codeine law
Cannabinol and derivativescannabinoid, psychoactive2009downgraded from class A to class C in 2004 [22] and upgraded to class B in 2009 [23] (Legalised for medicinal use in July 2018, and law excludes cannabidiol entirely)
Cannabis Cannabis, Green, Hash, Marijuana, Pot, Puff, Gas, Bud, Skunk, Ganja, Weed (among others)cannabinoid, psychedelicAll cannabis varieties, including those grown as hemp, are controlled under the act, not just drug varieties
Downgraded from class B to class C in 2004 [22] and upgraded to class B in 2009 [23]
Dihydrocodeine Paracodine, Synalgos DCopioid1971legal in amounts up to 30 mg prescribed by doctor in tablet form and compounded with an adjunct non-opioid such as paracetamol.
Ethylmorphine Codethyline
Glutethimide Doridensedative1985
Ketamine Ketalar, Special K, Ket, Kenny, Kenneth, horse tranquillisersedative2006, [24] moved to class B in 2014 [25] Used by Doctors on Air Ambulance duties to provide pain relief for serious or life-threatening injuries in extreme circumstances, when casualty sedation is required prior to a potential RSI.
Lefetamine stimulant1985
Lisdexamfetamine Elvanse in the UK, Vyvanse in the US2014 [25]
Mecloqualone sedative1984
a-Methylphenethylhydroxylamine 2001 [19]
Methaqualone Ludes, Mandrake, Mandrax, Quaaludesedative1984
Methcathinone stimulant1998 [13]
Methoxetamine dissociative2013 [26]
4–Methylmethcathinone MCAT, Mephedrone, Meow Meow, Bath Saltsstimulant2010 [27]
Methylone M1
Methylphenidate Ritalin, Concerta1971
Methylphenobarbitone sedative1984
Naphyrone NRG-1stimulant2010
Nicocodeine opioid1971
Nicodicodine 1973
Norcodeine 1971
Pentazocine Talwin, Fortal1985
Phenmetrazine Preludinstimulant1971
Pholcodine opioid
Propiram 1973
Zipeprol 1998 [13]

(aa) [28] Compounds structurally derived from 2–amino–1–phenyl–1–propanone by certain modifications.

(ab) [28] Compounds structurally derived from 2–aminopropan–1–one by certain modifications.

(b) any 5,5 disubstituted barbituric acid.

(c) [29] and (ca) [30] A number of categories of synthetic cannabinoids.

(d) [29] 1-Phenylcyclohexylamine or compounds structurally derived from 1-phenylcyclohexylamine or 2-amino-2-phenylcyclohexanone by certain modifications (that are not already class A substances).

(e) Any compound structurally derived from 1-benzofuran, 2,3-dihydro-1-benzofuran, 1H-indole, indoline, 1H-indene, or indane by certain modifications.

2. Any stereoisomeric form of a class B substance.

3. Any salt of a class B substance.

4. Any preparation or other product containing a class B substance, exluding those designed for administration by injection which are class A.

Class C drugs

1. The following substances, namely:— [11] [ non-primary source needed ]

(a)

Name as specified
in the Act
Brand or
street name
Drug typeYear
added
Notes and comments
Adinazolam Deracynbenzodiazepine2017
Alprazolam Xanax1985
Aminorex stimulant1998 [13]
Benzphetamine Didrex 1971metabolised into amphetamine and methamphetamine
Bromazepam Lexotanbenzodiazepine1985
Brotizolam Lendormin1998 [13]
Buprenorphine Subutex, Buprenexopioid1989used for opioid replacement therapy to treat addiction
Camazepam benzodiazepine1985
Cathine stimulant1986 Khat (Catha edulis), the plant in which Cathine originates, is now also illegal in the UK [31] [32]
Cathinone Khat (Catha edulis), the plant in which Cathinone originates, is now also illegal in the UK [31] [32]
Chlordiazepoxide Libriumbenzodiazepine1985
Chlorphentermine Apsedonstimulant1971
Clobazam Frisiumbenzodiazepine1985
Clorazepic acid Tranxène
Clonazepam Rivotril, Klonopin
Clotiazepam Clozan
Cloxazolam
Delorazepam
Dextropropoxyphene Darvon, Depronalopioid1983
Diazepam Valiumbenzodiazepine1985
Diethylpropion stimulant1984
Estazolam ProSombenzodiazepine1985
Ethchlorvynol Placidylsedative
Ethinamate
Etilamfetamine stimulant1986
Ethyl loflazepate benzodiazepine1985
Fencamfamine stimulant1971Removed from the schedule in 1973, added to the schedule again in 1986
Fenethylline 1986
Fenproporex
Fludiazepam benzodiazepine1985
Flunitrazepam Rohypnol
Flurazepam Dalmane, Staurodorm
Gabapentin [33] [34] NeurontinGabapentinoid2019
gamma-Butyrolactone GBLsedative2009Metabolised to GHB in the body. Classified in December 2009 [35]
Halazepam benzodiazepine1985
Haloxazolam
4-Hydroxy-n-butyric acid GHBsedative2003 [12]
Ketazolam benzodiazepine1985
Loprazolam Dormonoct
Lorazepam Ativan
Lormetazepam Noctamid, Loramet
Mazindol stimulant
Medazepam benzodiazepine
Mefenorex stimulant1986amphetamine derivative, metabolises to amphetamine
Mephentermine 1971
Meprobamate Miltownsedative1985
Mesocarb stimulant1998 [13] used to counteract the effects of benzodiazepines
Methyprylone sedative1985
Midazolam Versedbenzodiazepine1990
Nitrous Oxide WhippetsPsychedelic2023
Nimetazepam benzodiazepine1985
Nitrazepam Mogadon
Nordazepam Calmday
Oxazepam Seresta
Oxazolam
Pemoline stimulant1989
Phendimetrazine Bontril1971
Phentermine Fastin, Ionamin1985
Pinazepam benzodiazepine
Pipradrol stimulant1971
Propylhexedrine 1971legalised in 1995 [36]
Prazepam Lysanxiabenzodiazepine1985
Pregabalin Lyricagabapentinoid2019
Pyrovalerone stimulant1986
Temazepam Restoril, jelliesbenzodiazepine1985becomes class A when prepared for injection
Tetrazepam
Tramadol opioid2014 [25] Also functions as a weak SNRI.
Triazolam Halcionbenzodiazepine1985
Zaleplon Sonata nonbenzodiazepine 2014 [25]
Zolpidem Ambien2003 [12]
Zopiclone Imovane2014 [25]
N.B. Sub-paragraphs (b), (c), (d) and (e) all refer to anabolic steroids that were banned in 1996 [37] (unless referenced otherwise):

(b)

(c) Compounds structurally derived from 17-hydroxyandrostan-3-one or from 17-hydroxyestran-3-one by certain modifications, excluding Trilostane or a compounds listed above.

(ca) 1–benzylpiperazine or compounds structurally derived from 1–benzylpiperazine or 1–phenylpiperazine by certain modifications.

(d) any substance which is an ester and/or ether of a substance specified in (b) or (c) above.

(e)

Derivatives and analogues

The act contains several references to "derivatives" of compounds but the extent of this term is not fully clarified. Where unspecified it is thought to indicate derivatives which can be made from the specified compound in a single synthetic step, although such a definition would indicate that alkyllysergamide analogues would be uncontrolled. Where the derivatives are specified to be "structural derivatives" there is precedent that the statute applies whenever the structure could be converted to the specified derivatives in any number of synthetic steps. [38]

Penalties

The penalties for drug offences depend on the class of drug involved. These penalties are enforced against those who do not have a valid prescription or licence to possess the drug in question. Thus, it is not illegal for someone to possess heroin, a Class A drug, so long as it was administered to them legally (by prescription).

Class A drugs attract the highest penalty, and imprisonment is both "proper and expedient". [39] The maximum penalties possible are as follows: [40]

OffenceCourtClass AClass B/Temporary classClass C
Possession Magistrates 6 months / £5000 fine3 months / £2500 fine3 months / £500 fine
Crown 7 years / unlimited fine5 years / unlimited fine2 years / unlimited fine
Supply and possession
with intent to supply
Magistrates 6 months / £5000 fine6 months / £5000 fine3 months / £2000 fine
Crown Life [41] / unlimited fine14 years / unlimited fine14 years / unlimited fine

International cooperation

The act makes it a crime to assist in, incite, or induce, the commission of an offence, outside the UK, against another nation's corresponding law on drugs. A corresponding law is defined as another country's law "providing for the control and regulation in that country of the production, supply, use, export and import of drugs and other substances in accordance with the provisions of the Single Convention on Narcotic Drugs" or another drug control treaty to which the UK and the other country are parties. An example might be lending money to a United States drug dealer for the purpose of violating that country's Controlled Substances Act.

History

The Drugs (Prevention of Misuse) Act 1964 controlled amphetamines in the United Kingdom in advance of international agreements and was later used to control LSD.

Before 1971, the UK had a relatively liberal drugs policy and it was not until United Nations influence had been brought to bear that controlling incidental drug activities was employed to effectively criminalise drugs use. It is noted that bar the smoking of opium and cannabis; Section 8, part d, under the Misuse of Drugs Act 1971 was not an offence (relating to the prosecution of the owner of a premises/building inside of which controlled drugs were being used). Section 8 of the Misuse of Drugs Act 1971 [42] was amended by Regulation 13 of Misuse of Drugs Regulations 1985 (SI 1985/2066) [43] and Section 38 of the Criminal Justice and Police Act 2001. [44] These amendments were however repealed in 2005 by Schedule 1 (part 6) of the Drugs Act 2005,. [45] [46]

The Current Section 8 covers: people knowingly allowing premises they own, manage, or have responsibility for, to be used by any other person for:

Criticism and controversy

Notable criticism of the act includes:

The Transform Drug Policy Foundation offers rational criticism of the harms caused by the Government's current prohibitionist drug policy. [51] The Drug Equality Alliance (DEA) has launched legal actions against the UK Government's partial and unequal administration of the Act's discretionary powers, making particular reference to the arbitrary exclusion of alcohol and tobacco on the subjective grounds of historical and cultural precedents contrary to the Act's policy and objects. [52]

Classification of cannabis has become especially controversial. In 2004, cannabis [6] was reclassified from class B to class C, [22] in accordance with advice from the Advisory Council on the Misuse of Drugs (ACMD). In 2009, it was returned to class B, [23] against ACMD advice.

In February 2009 the UK government was accused by its most senior expert drugs adviser Professor David Nutt of making a political decisions with regard to drug classification in rejecting the scientific advice to downgrade ecstasy from a class A drug. The Advisory Council on the Misuse of Drugs (ACMD) report on ecstasy, based on a 12-month study of 4,000 academic papers, concluded that it is nowhere near as dangerous as other class A drugs such as heroin and crack cocaine, and should be downgraded to class B. The advice was not followed. [53] Jacqui Smith, then Home Secretary, was also widely criticised by the scientific community for bullying Professor David Nutt into apologising for his comments that, in the course of a normal year, more people died from falling off horses than died from taking ecstasy. [54] Professor Nutt was later sacked by Alan Johnson (Jacqui Smith's successor as Home Secretary); Johnson saying "It is important that the government's messages on drugs are clear and as an advisor you do nothing to undermine public understanding of them. I cannot have public confusion between scientific advice and policy and have therefore lost confidence in your ability to advise me as Chair of the ACMD." [55] [56]

In May 2011, a report named Taking Drugs Seriously was released by Demos. It discusses several issues with the current system, since its enactment in 1971. It states that the constant presence of new drugs will make it difficult for the government to keep up with the latest situation - over 600 drugs are now classified under the act. Comparison levels of harm previously demonstrated by David Nutt show that alcohol and tobacco were among the most lethal, while some class A drugs, such as MDMA, LSD, and magic mushrooms, were among the least harmful. [57]

Use of controlled substances for research

A common misunderstanding amongst researchers is that most national laws (including the Misuse for Drugs Act) allows the use of small amounts of a controlled substance for non-clinical / non-in vivo research without licences. A typical use case might be having a few milligrams or microlitres of a controlled substance within larger chemical collections (often tens of thousands of chemicals) for in vitro screening. Researchers often believe that there is some form of "research exemption" for such small amounts. This incorrect view may be further re-enforced by R&D chemical suppliers often stating and asking scientists to confirm that anything bought is for research use only.

A further misconception is that the Misuse of Drugs Act simply lists a few hundred substances (e.g. MDMA, Fentanyl, Amphetamine, etc.) and compliance can be achieved via checking a CAS number, chemical name or similar identifier. However, the reality is that in most cases all ethers, esters, salts and stereo isomers are also controlled and it is impossible to simply list all of these. The act contains several "generic statements" or "chemical space" laws, which aim to control all chemicals similar to the "named" substance, these provide detailed descriptions similar to Markushes, a good example of a few of these are found in the Misuse of Drugs Act 1971 (amendment) order 2013. [58]

Due to this complexity in legislation the identification of controlled chemicals in research is often carried out computationally, either by in house systems maintained a company's sample logistics department or by the use commercial software solutions. [59] Automated systems are often required as many research operations can often have chemical collections running into 10Ks of molecules at the 1–5 mg scale, which are likely to include controlled substances, especially within medicinal chemistry research, even if the core research of the company is not narcotic or psychotropic drugs. [60] These may not have been controlled when created, but they have subsequently been declared controlled, or fall within chemical space close to known controlled substances.

There are no specific research exemptions in the Misuse of Drugs Act 1971. However, the associated Misuse of Drugs Regulations 2001 (SI 2001/3998) [61] does exempt products containing less than 1 mg of a controlled substance (1 μg for lysergide and derivatives) so long as a number of requirements are met, including that it cannot be recovered by readily applicable means, does not pose a risk to human health and is not meant for administration to a human or animal.

Although this does at first seem to allow research use, in most circumstances the sample, by definition, is "recoverable" - in order to prepare it for use the sample is "recovered" into an assay buffer or solvent such as DMSO or water. In 2017 the Home Office also confirmed that the 1 mg limit applies to the total of all preparations across the entire container in the case of sample microtitre plates. [62] Given this, most companies and researchers choose not to rely on this exemption.

However according to Home Office licensing, "University research departments generally do not require licences to possess and supply drugs in schedules 2, 3, 4 part I, 4 part II and schedule 5, but they do require licences to produce any of those drugs and to produce, possess and/or supply drugs in schedule 1". [63]

See also

Notes

  1. Plants containing mescaline not illegal, only an extract of the substance.

References

UKOpenGovernmentLicence.svg  This article incorporates text published under the British Open Government Licence  v3.0: To maintain the accuracy of the article, some of the text is copied directly from the legislation.

  1. 1 2 The citation of this act by this short title is authorised by section 40(1) of this act.
  2. "Single Convention on Narcotic Drugs, 1961, United Nations Office on Drugs and Crime website, accessed 6 February 2009". Unodc.org. 24 October 2007. Retrieved 23 January 2011.
  3. "Convention on Psychotropic Substances, 1971, United Nations Office on Drugs and Crime website, accessed 6 February 2009". Unodc.org. 24 October 2007. Retrieved 23 January 2011.
  4. "Convention against the Illicit Traffic in Narcotic Drugs and Psychotropic Substances, 1988, United Nations Office on Drugs and Crime website, accessed 6 February 2009". Unodc.org. 24 October 2007. Retrieved 23 January 2011.
  5. "Misuse of Drugs Act, Home Office representation of the act, Home Office website, accessed 27 January 2009". Drugs.homeoffice.gov.uk. Archived from the original on 4 May 2010. Retrieved 23 January 2011.
  6. 1 2 All varieties of cannabis, including those grown as hemp, are controlled under the act, not just drug varieties.
  7. Statutory Instrument 2001 No. 3998 The Misuse of Drugs Regulations 2001
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