Route 608 or Highway 608 may refer to:
| Preceded by 607 | Lists of highways 608 | Succeeded by 609 |
State Route 608 (SR 608) is a north–south state highway in the northeastern portion of the U.S. state of Ohio. Its southern terminus is at State Route 528 about 2 miles (3.2 km) south of Middlefield. The northern terminus is at Ravenna Road about 4 miles (6.4 km) south of Painesville. The route passes through one of the largest Amish settlements in Ohio; an Amish-run cheese factory is located at Nauvoo Road north of Middlefield.
