The following highways are numbered 381:
Interstate 381 
Georgia State Route 381 (former)
Kentucky Route 381 
Maryland Route 381 
New York State Route 381 (former)
North Carolina Highway 381 
Pennsylvania Route 381 
Puerto Rico Highway 381 
South Carolina Highway 381 
Tennessee State Route 381 
Virginia State Route 381 | Preceded by 380 | Lists of highways 381 | Succeeded by 382 |
North Carolina Highway 79 (NC 79) is an 8.7-mile-long (14.0 km) primary state highway in the U.S. state of North Carolina. NC 79 runs from the South Carolina border as a continuation of South Carolina Highway 79 at Gibson to U.S. Route 15 (US 15), US 401, US 501, and US 74 Business in Laurinburg. While signed north–south, NC 79 physically travels in an east–west direction between its termini. NC 79 is primarily a two-lane road running through rural Scotland County and residential areas west of Laurinburg. Combined with SC 79, the highways form a coherent route between SC 9 northwest of Bennettsville, South Carolina and Laurinburg.
