Route 405 or Highway 405 may refer to:
Interstate 405 
Georgia State Route 405 (unsigned designation for Interstate 95)
Maryland Route 405 
Pennsylvania Route 405 
Puerto Rico Highway 405 
Virginia State Route 405 | Preceded by 404 | Lists of highways 405 | Succeeded by 406 |
Interstate 5 (I-5) is the main north–south Interstate Highway on the West Coast of the United States, running largely parallel to the Pacific Coast of the contiguous U.S. from Mexico to Canada. It travels through the states of California, Oregon, and Washington, serving several large cities on the West Coast, including San Diego, Los Angeles, Sacramento, Portland, and Seattle. It is the only continuous Interstate highway to touch both the Mexican and Canadian borders. Upon crossing the Mexican border at its southern terminus, the highway continues to Tijuana, Baja California, as Mexican Federal Highway 1 (Fed. 1). Upon crossing the Canadian border at its northern terminus, it continues to Vancouver as British Columbia Highway 99 (BC 99).
Interstate 405 may refer to:
