The following highways are numbered 622:
| Preceded by 621 | Lists of highways 622 | Succeeded by 623 |
West Virginia Route 622 is a north–south state highway located entirely in Kanawha County, West Virginia. The southern terminus of the route is at West Virginia Route 25 west of Institute. The northern terminus is at Interstate 77 exit 114 north of Pocatalico.
State Route 35 is a primary state highway in the U.S. state of Virginia. The state highway runs 48.71 miles (78.39 km) from the North Carolina state line near Boykins, where the highway continues as North Carolina Highway 35, north to SR 605 and SR 622 in Templeton. SR 35 is the main north–south highway of Southampton County; the highway also connects U.S. Route 58 in Courtland with Interstate 95 (I-95) and US 301 at Templeton south of Petersburg.
State Route 271 is a primary state highway in the U.S. state of Virginia. Known as Pouncey Tract Road, the state highway runs 7.34 miles (11.81 km) from U.S. Route 250 in Short Pump north to SR 620 and SR 622 in Rockville. A small section of it was first added to the state highway system during 1930, and it gained its current routing and designation by 1940.
Secondary Highway 622, commonly referred to as Highway 622, is a provincially maintained secondary highway in the Canadian province of Ontario. It is a long connecting route between Highways 11 and Highway 17 in Northwestern Ontario. The road is connected to Highway 11 by the 3 km-long spur road Highway 11B in Atikokan.
National Route 236 is a national highway connecting Obihiro, Hokkaido and Urakawa, Hokkaido in Japan.
King's Highway 109, or Highway 109, is a former provincial highway in Ontario. It was used on two separate, unrelated routes during the 1950s and 1960s:
Tyler Heights, also known as Flatwoods, is an unincorporated community in Kanawha County, West Virginia, United States. Tyler Heights is located along West Virginia Route 622 at its junction with West Virginia Route 501, 5 miles (8.0 km) east-northeast of Nitro.
Secondary Highway 500, commonly referred to as Highway 500, was a secondary highway in the Canadian province of Ontario which was first designated in 1956. Its route was renumbered in 1964, becoming:
Kentucky Route 622 is a rural secondary state highway in South Central Kentucky. The 20.020-mile-long (32.219 km) route traverses eastern Simpson and south-central Warren Counties.
Old Bridge Road is the name of multiple highways in the United States:
Secondary Highway 514, commonly referred to as Highway 514, was a secondary highway in the Canadian province of Ontario. It was used on two separate routes from the 1950s to the 1990s:
