Oxanamide

Last updated
Oxanamide
Oxanamide.png
Clinical data
ATC code
  • none
Identifiers
  • 2-ethyl-3-propyloxirane-2-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C8H15NO2
Molar mass 157.213 g·mol−1
3D model (JSmol)
  • CCCC1C(O1)(CC)C(=O)N
  • InChI=1S/C8H15NO2/c1-3-5-6-8(4-2,11-6)7(9)10/h6H,3-5H2,1-2H3,(H2,9,10)
  • Key:WBLPIVIXQOFTPQ-UHFFFAOYSA-N
   (verify)

Oxanamide (Quiactin) is an anxiolytic and muscle relaxant which can produce sedative and hypnotic effects in sufficiently high doses. [1] An uncontrolled trial on patients treated in a clinical gynecology practice published in 1959 found that oxanamide was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects. [2]

References

  1. ↑ Kuhn WL, Ketteler HJ, Van Maanen EF (January 1960). "Effects of oxanamide on the central nervous system". Proceedings of the Society for Experimental Biology and Medicine. 103: 101–3. doi:10.3181/00379727-103-25425. PMID   14412594. S2CID   40927309.
  2. ↑ Woodhull RB (April 1959). "Oxanamide; adjunctive use of a new tranquilizer in gynecology". California Medicine. 90 (4): 275–7. PMC   1577644 . PMID   13638840.


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