Percavirus

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Percavirus
Virus classification Red Pencil Icon.png
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Herpesviridae
Subfamily: Gammaherpesvirinae
Genus:Percavirus
Type species
Equid gammaherpesvirus 2
Species

See text

Percavirus is a genus of viruses in the order Herpesvirales , in the family Herpesviridae , in the subfamily Gammaherpesvirinae . Mammals serve as natural hosts. There are currently six species in this genus including the type species Equid gammaherpesvirus 2 . Diseases associated with this genus include: conjunctivitis, immunosuppression in foals, pneumonia, respiratory disease. [1] [2]

Contents

Species

The genus consists of the following six species: [2]

Structure

Viruses in Percavirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length. [1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
PercavirusSpherical pleomorphicT=16EnvelopedLinearMonopartite

Life cycle

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Mammals serve as the natural host. [1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
PercavirusMammalsB-lymphocytesGlycoprotiensBuddingNucleusNucleusSex; saliva

Related Research Articles

Rhadinovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. Humans and other mammals serve as natural hosts. There are currently nine species in this genus including the type species Saimiriine gammaherpesvirus 2. Diseases associated with this genus include: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, caused by Human gammaherpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). The term rhadino comes from the Latin fragile, referring to the tendency of the viral genome to break apart when it is isolated.

Mardivirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Chickens, turkeys, and quail serve as natural hosts. There are currently five species in this genus including the type species Gallid herpesvirus 2. Diseases associated with this genus include: Marek's disease, which causes asymmetric paralysis of one or more limbs, neurological symptoms, and development of multiple lymphomas that manifest as solid tumors. Gallid herpesvirus 2 is the only one of these viruses known to be pathogenic and due to the antigenic similarity between the three viruses the other two have been used to vaccinate against Marek's disease. These viruses have double stranded DNA genomes with no RNA intermediate.

<i>Alphaherpesvirinae</i> subfamily of viruses

Alphaherpesvirinae is a subfamily of viruses in the family Herpesviridae, primarily distinguished by reproducing more quickly than other subfamilies in the Herpesviridae. In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and Bovine herpesvirus 1 is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. Mammals serve as natural hosts. There are currently 42 species in this subfamily, divided among 5 genera with one species unassigned to a genus. Diseases associated with this subfamily include: HHV-1 and HHV-2: skin vesicles or mucosal ulcers, rarely encephalitis and meningitis, HHV-3: chickenpox (varicella) and shingles, GaHV-2: Marek's disease.

<i>Gammaherpesvirinae</i> subfamily of viruses

Gammaherpesvirinae is a subfamily of viruses in the order Herpesvirales and in the family Herpesviridae. Viruses in Gammaherpesvirinae are distinguished by reproducing at a more variable rate than other subfamilies of Herpesviridae. Mammals serve as natural hosts. There are currently 39 species in this subfamily, divided among 4 genera with three species unassigned to a genus. Diseases associated with this subfamily include: HHV-4: infectious mononucleosis. HHV-8: kaposi's sarcoma.

Betaherpesvirinae is a subfamily of viruses in the order Herpesvirales and in the family Herpesviridae. Mammals serve as natural hosts. There are currently 25 species in this subfamily, divided among 4 genera with two species unassigned to a genus. Diseases associated with this subfamily include: human cytomegalovirus (HHV-5): congenital CMV infection; HHV-6: 'sixth disease' ; HHV-7: symptoms analogous to the 'sixth disease'.

Varicellovirus (var′i-sel′ō-vi′rŭs) is a genus of viruses belonging to subfamily Alphaherpesvirinae, a member of family Herpesviridae. Humans and mammals serve as natural hosts. There are currently 18 species in this genus including the type species Human alphaherpesvirus 3 also known as Varicella zoster virus (VZV). Diseases associated with this genus include: HHV-3—chickenpox (varicella) and shingles; BoHV-1—infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IPV); SuHV-1 —Aujesky's disease characterized by central nervous system signs, high mortality rates in young animals, and respiratory illness in older pigs.

<i>Iltovirus</i> genus of viruses

Iltovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Birds, galliform birds, psittacine birds, chickens, turkeys, and quail serve as natural hosts. There are currently only two species in this genus including the type species Gallid alphaherpesvirus 1. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease.

<i>Lymphocryptovirus</i> Genus of viruses

Lymphocryptovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. This genus includes the human-infecting Human gammaherpesvirus 4, as well as viruses that infect both Old World monkeys and New World monkeys. Other names for the Lymphocryptovirus genus include Lymphocryptoviridae and gamma-1 herpesviruses. There are currently nine species in this genus including the type species Human gammaherpesvirus 4. Diseases associated with this genus include: mononucleosis, Burkitt's lymphoma, and nasopharyngeal carcinoma.

<i>Simplexvirus</i> genus of viruses

Simplexvirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Humans and mammals serve as natural hosts. Diseases associated with this genus include skin vesicles or mucosal ulcers, rarely encephalitis, and meningitis.

<i>Orthohepadnavirus</i> genus of viruses

Orthohepadnavirus is a genus of viruses, in the family Hepadnaviridae. Humans and other mammals serve as natural hosts. There are currently 12 species in this genus including the type species Hepatitis B virus. Diseases associated with this genus include: hepatitis, hepatocellular carcinoma, and cirrhosis.

Muromegalovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. Rodents serve as natural hosts. There are currently three species in this genus including the type species Murid betaherpesvirus 1. Diseases associated with this genus include: infected peritoneal macrophages, dendritic cells (DC) and hepatocytes, inducing significant pathology in both the spleen and the liver. Murid viruses Murid betaherpesvirus 1 (MuHV-1) and Murid betaherpesvirus 2 (MuHV-2), previously defined as mouse cytomegalovirus (MCMV) and rat cytomegalovirus (RCMV), belong to this genus.

Babuvirus is a genus of viruses, in the family Nanoviridae. Musa species serve as natural hosts. There are currently three species in this genus including the type species Banana bunchy top virus. Diseases associated with this genus include: stunting, severe necrosis and early plant death. BBTV induces banana bunchy top disease (BBTD).

Betapapillomavirus is a genus of viruses, in the family Papillomaviridae. Human serve as natural hosts. There are currently six species in this genus including the type species Betapapillomavirus 1. Diseases associated with this genus include warts, papilloma, and malignant tumours.

Curtovirus is a genus of ssDNA viruses, in the family Geminiviridae. Dicotyledonous plants serve as natural hosts. Curtoviruses are transmitted by leafhoppers. The type species is Beet curly top virus. Diseases associated with this genus include: Curly top disease.

Ictalurivirus is a genus of viruses in the order Herpesvirales, in the family Alloherpesviridae. Fish serve as natural hosts. There are currently three species in this genus including the type species Ictalurid herpesvirus 1. Diseases associated with this genus include: channel catfish disease.

Macavirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. Mammals serve as natural hosts. There are currently nine species in this genus including the type species Alcelaphine herpesvirus 1. Diseases associated with this genus include: inapparent infection in their reservoir hosts, but fatal lymphoproliferative disease when they infect MCF-susceptible hosts, including cattle, deer, bison, water buffalo and pigs.

Topocuvirus is a genus of viruses, in the family Geminiviridae. Dicotyledonous plants serve as natural hosts. There is currently only one species in this genus: the type species Tomato pseudo-curly top virus. Diseases associated with this genus include: vein swelling, curling of the leaves and leaf distortion.

Scutavirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Alphaherpesvirinae. Turtles and tortoises serve as natural hosts. Diseases associated with this genus include fibropapillomatosis.

Batrachovirus is a genus of viruses in the order Herpesvirales, in the family Alloherpesviridae. Frogs serve as natural hosts. There are currently three species in this genus, including the type species Ranid herpesvirus 1. Diseases associated with this genus include: raHV-1: Lucké tumor.

Kappatorquevirus is a genus of viruses, in the family Anelloviridae. Pigs serve as natural hosts. There are currently two species in this genus including the type species Torque teno sus virus k2. Diseases associated with this genus include: possibly post-weaning multisystemic wasting syndrome (PMWS).

References

  1. 1 2 3 "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. 1 2 "Virus Taxonomy: 2019 Release". talk.ictvonline.org. International Committee on Taxonomy of Viruses. Retrieved 9 May 2020.