SLC2A13

SLC2A13
Identifiers
Aliases	SLC2A13 , HMIT, solute carrier family 2 member 13
External IDs	OMIM: 611036; MGI: 2146030; HomoloGene: 43139; GeneCards: SLC2A13; OMA:SLC2A13 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q12 Start 39,755,025 bp [1] End 40,106,089 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 E3 Start 91,151,899 bp [2] End 91,457,464 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus pars reticulata endothelial cell pars compacta Brodmann area 23 Brodmann area 46 external globus pallidus superior frontal gyrus entorhinal cortex middle temporal gyrus Top expressed in olfactory tubercle suprachiasmatic nucleus habenula dorsal striatum nucleus accumbens subiculum substantia nigra medial dorsal nucleus lateral septal nucleus paraventricular nucleus of hypothalamus More reference expression data BioGPS n/a
Gene ontology Molecular function transporter activity carbohydrate:proton symporter activity transmembrane transporter activity glucose transmembrane transporter activity myo-inositol:proton symporter activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process glucose import transmembrane transport myo-inositol transport proton transmembrane transport hexose transmembrane transport glucose transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114134 239606 Ensembl ENSG00000151229 ENSMUSG00000036298 UniProt Q96QE2 Q3UHK1 RefSeq (mRNA) NM_052885 NM_001033633 RefSeq (protein) NP_443117 NP_001028805 Location (UCSC) Chr 12: 39.76 – 40.11 Mb Chr 15: 91.15 – 91.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Proton myo-inositol cotransporter, also known as solute carrier family 2 member 13 is a protein that in humans is encoded by the SLC2A13 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000151229 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036298 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "SLC2A13 solute carrier family 2 member 13 [ Homo sapiens (human) ]" . Retrieved 2021-04-18.

Further reading

• Uldry M, Ibberson M, Horisberger JD, Chatton JY, Riederer BM, Thorens B (August 2001). "Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain". The EMBO Journal. 20 (16): 4467–77. doi:10.1093/emboj/20.16.4467. PMC   125574 . PMID   11500374.
• Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL (July 2004). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics. 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID   15203218.
• Bankovic J, Stojsic J, Jovanovic D, Andjelkovic T, Milinkovic V, Ruzdijic S, Tanic N (February 2010). "Identification of genes associated with non-small-cell lung cancer promotion and progression". Lung Cancer. 67 (2): 151–9. doi:10.1016/j.lungcan.2009.04.010. PMID   19473719.
• Di Daniel E, Mok MH, Mead E, Mutinelli C, Zambello E, Caberlotto LL, Pell TJ, Langmead CJ, Shah AJ, Duddy G, Kew JN, Maycox PR (July 2009). "Evaluation of expression and function of the H+/myo-inositol transporter HMIT". BMC Cell Biology. 10: 54. doi: 10.1186/1471-2121-10-54 . PMC   2717050 . PMID   19607714.
• Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T (December 2009). "Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease". Nature Genetics. 41 (12): 1303–7. doi:10.1038/ng.485. PMID   19915576. S2CID   205356259.