Monocarboxylate transporter 9

SLC16A9
Identifiers
Aliases	SLC16A9 , C10orf36, MCT9, solute carrier family 16 member 9
External IDs	OMIM: 614242 MGI: 1914109 HomoloGene: 32642 GeneCards: SLC16A9
Gene location (Human)
Chr.	Chromosome 10 (human)
End	59,736,002 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	70,121,798 bp
RNA expression pattern
	Top expressed in
	kidney; ; gums; ; rectum; ; palpebral conjunctiva; ; bronchial epithelial cell; ; right uterine tube; ; ganglionic eminence; ; spleen; ; caput epididymis; ; islet of Langerhans;
	Top expressed in
	retinal pigment epithelium; ; meninges; ; kidney; ; right lung; ; right lung lobe; ; proximal tubule; ; ciliary body; ; aortic valve; ; sciatic nerve; ; pineal gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; symporter activity ; monocarboxylic acid transmembrane transporter activity ;
Cellular component	plasma membrane ; membrane ; integral component of membrane ; integral component of plasma membrane ;
Biological process	urate metabolic process ; transmembrane transport ; monocarboxylic acid transport ;
	Sources:Amigo / QuickGO
Orthologs
	220963
	66859
	ENSG00000165449
	ENSMUSG00000037762
	Q7RTY1
	Q7TM99
NM_194298 ; NM_001323977 ; NM_001323978 ; NM_001323979 ; NM_001323980 ;
	NM_001323981
	NM_025807
NP_001310906 ; NP_001310907 ; NP_001310908 ; NP_001310909 ; NP_001310910 ;
	NP_919274
	NP_080083
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 04, 2023

Monocarboxylate transporter 9 (MCT9, solute carrier family 16, member 9, SLC16A9) is a protein that in humans is encoded by the SLC16A9 gene.^[5]

Clinical relevance

Mutations in the SLC16A9 gene have been associated with carnitine levels in blood.^[6]

Related Research Articles

Excitatory amino-acid transporter 5 (EAAT5) is a protein that in humans is encoded by the SLC1A7 gene.

Excitatory amino-acid transporter 4 (EAAT4) is a protein that in humans is encoded by the SLC1A6 gene.

Sialin, also known as H(+)/nitrate cotransporter and H(+)/sialic acid cotransporter, is a protein which in humans is encoded by the SLC17A5 gene.

Monocarboxylate transporter 5 is a protein that in humans is encoded by the SLC16A4 gene.

Sodium bicarbonate transporter-like protein 11 is a protein that in humans is encoded by the SLC4A11 gene.

Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene.

Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene.

Large neutral amino acids transporter small subunit 2 is a protein that in humans is encoded by the SLC7A8 gene.

Monocarboxylate transporter 4 (MCT4) also known as solute carrier family 16 member 3 is a protein that in humans is encoded by the SLC16A3 gene.

Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.

Solute carrier organic anion transporter family member 4A1 is a protein that in humans is encoded by the SLCO4A1 gene.

Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene.

Solute carrier family 13 member 3 also called sodium-dependent dicarboxylate transporter (NaDC3) is a protein that in humans is encoded by the SLC13A3 gene.

Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.

Asc-type amino acid transporter 1 (Asc-1) is a protein that in humans is encoded by the SLC7A10 gene.

Monocarboxylate transporter 10, also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene. SLC16A10 is a member of the solute carrier family.

Solute carrier family 12 member 9 (SLC12A9), also known as cation-chloride cotransporter 6 (CCC6) or cation-chloride cotransporter-interacting protein 1 (CIP1), is a protein that in humans is encoded by the SLC12A9 gene.

Solute carrier family 17, member 3 is a protein that in humans is encoded by the SLC17A3 gene.

N-acetyltransferase 8 is a protein that in humans is encoded by the NAT8 gene.

Solute carrier family 16 member 12 is a protein that in humans is encoded by the SLC16A12 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000165449 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037762 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: solute carrier family 16".
↑ Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF (September 2011). "Human metabolic individuality in biomedical and pharmaceutical research". Nature. 477 (7362): 54–60. Bibcode:2011Natur.477...54S. doi:10.1038/nature10354. PMC 3832838 . PMID 21886157.

Kolz M, Johnson T, Sanna S, et al. (2009). "Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations". PLOS Genet. 5 (6): e1000504. doi: 10.1371/journal.pgen.1000504 . PMC 2683940 . PMID 19503597.
Gunjaca G; Boban M; PehliÄ‡ M; et al. (2010). "Predictive value of 8 genetic loci for serum uric acid concentration". Croat. Med. J. 51 (1): 23–31. doi:10.3325/cmj.2010.51.23. PMC 2829178 . PMID 20162742.
Grupe A, Li Y, Rowland C, et al. (2006). "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease". Am. J. Hum. Genet. 78 (1): 78–88. doi:10.1086/498851. PMC 1380225 . PMID 16385451.
Polasek O; JeronciÄ‡ I; MuliÄ‡ R; et al. (2010). "Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series". Croat. Med. J. 51 (1): 32–9. doi:10.3325/cmj.2010.51.32. PMC 2829186 . PMID 20162743.
Stark K, Reinhard W, Grassl M, et al. (2009). "Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease". PLOS ONE. 4 (11): e7729. Bibcode:2009PLoSO...4.7729S. doi: 10.1371/journal.pone.0007729 . PMC 2766838 . PMID 19890391.
van der Harst P, Bakker SJ, de Boer RA, et al. (2010). "Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms". Hum. Mol. Genet. 19 (2): 387–95. doi: 10.1093/hmg/ddp489 . PMID 19861489.
Illig T, Gieger C, Zhai G, et al. (2010). "A genome-wide perspective of genetic variation in human metabolism". Nat. Genet. 42 (2): 137–41. doi:10.1038/ng.507. PMC 3773904 . PMID 20037589.
Halestrap AP, Meredith D (2004). "The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond". Pflügers Arch. 447 (5): 619–28. doi:10.1007/s00424-003-1067-2. PMID 12739169. S2CID 15498611.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000165449 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037762 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: solute carrier family 16".

[pmid21886157-6] Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF (September 2011). "Human metabolic individuality in biomedical and pharmaceutical research". Nature. 477 (7362): 54–60. Bibcode:2011Natur.477...54S. doi:10.1038/nature10354. PMC 3832838 . PMID 21886157.

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Monocarboxylate transporter 9

Contents

Clinical relevance

Related Research Articles

References

Further reading