SLC12A9

SLC12A9
Identifiers
Aliases	SLC12A9 , CCC6, CIP1, WO3.3, hCCC6, solute carrier family 12 member 9
External IDs	OMIM: 616861 MGI: 1933532 HomoloGene: 5429 GeneCards: SLC12A9
Gene location (Human)
Chr.	Chromosome 7 (human)
End	100,867,010 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	137,333,597 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; spleen; ; lymph node; ; upper lobe of left lung; ; right coronary artery; ; left uterine tube; ; gallbladder; ; appendix; ; canal of the cervix;
	Top expressed in
	secondary oocyte; ; yolk sac; ; internal carotid artery; ; external carotid artery; ; superior frontal gyrus; ; blood; ; saccule; ; bone marrow; ; cerebellar cortex; ; otic placode;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium:chloride symporter activity ; transporter activity ; cation:chloride symporter activity ;
Cellular component	extracellular exosome ; plasma membrane ; membrane ; integral component of membrane ;
Biological process	ion transport ; transmembrane transport ; potassium ion transmembrane transport ; chloride transmembrane transport ; chloride transport ; transport ; cell volume homeostasis ; chloride ion homeostasis ; potassium ion homeostasis ; potassium ion import across plasma membrane ;
	Sources:Amigo / QuickGO
Orthologs
	56996
	83704
	ENSG00000146828
	ENSMUSG00000037344
	Q9BXP2
	Q99MR3
	NM_001267812 ; NM_001267814 ; NM_020246 ; NM_001363493 ; NM_001363494
	NM_031406 ; NM_001359611
	NP_001254741 ; NP_001254743 ; NP_064631 ; NP_001350422 ; NP_001350423
	NP_113583 ; NP_001346540
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Solute carrier family 12 member 9 (SLC12A9), also known as cation-chloride cotransporter 6 (CCC6) or cation-chloride cotransporter-interacting protein 1 (CIP1), is a protein that in humans is encoded by the SLC12A9 gene.^[5]^[6]^[7]

Related Research Articles

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The sodium-chloride symporter (also known as Na⁺-Cl⁻ cotransporter, NCC or NCCT, or as the thiazide-sensitive Na⁺-Cl⁻ cotransporter or TSC) is a cotransporter in the kidney which has the function of reabsorbing sodium and chloride ions from the tubular fluid into the cells of the distal convoluted tubule of the nephron. It is a member of the SLC12 cotransporter family of electroneutral cation-coupled chloride cotransporters. In humans, it is encoded by the SLC12A3 gene (solute carrier family 12 member 3) located in 16q13.

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Sodium bicarbonate cotransporter 3 is a protein which in humans is encoded by the SLC4A7 gene.

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<span class="mw-page-title-main">Electroneutral sodium bicarbonate exchanger 1</span> Protein-coding gene in the species Homo sapiens

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Solute carrier family 12 member 7 is a protein that in humans is encoded by the SLC12A7 gene.

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.

Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene.

Sodium-dependent phosphate transport protein 1 is a protein that in humans is encoded by the SLC17A1 gene.

Solute carrier family 13 member 3 also called sodium-dependent dicarboxylate transporter (NaDC3) is a protein that in humans is encoded by the SLC13A3 gene.

Solute carrier family 13 member 2 is a protein that is encoded in humans by the SLC13A2 gene.

P3 protein is a protein that in humans is encoded by the SLC10A3 gene.

Sodium/bile acid cotransporter 7 is a protein which in humans is encoded by the SLC10A7 gene.

Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.

Solute carrier family 12 member 8 (SLC12A8), also known as cation-chloride cotransporter 9 (CCC9), is a protein that in humans is encoded by the SLC12A8 gene.

Proton myo-inositol cotransporter, also known as solute carrier family 2 member 13 is a protein that in humans is encoded by the SLC2A13 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000146828 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037344 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: solute carrier family 12 (potassium/chloride transporters)".
↑ Caron L; Rousseau F; Gagnon E; Isenring P (October 2000). "Cloning and functional characterization of a cation-Cl⁻ cotransporter-interacting protein". J. Biol. Chem. 275 (41): 32027–36. doi: 10.1074/jbc.M000108200 . PMID 10871601.
↑ Wilson MD; Riemer C; Martindale DW; Schnupf P; Boright AP; Cheung TL; Hardy DM; Schwartz S; Scherer SW; Tsui LC; Miller W; Koop BF (March 2001). "Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5". Nucleic Acids Res. 29 (6): 1352–65. doi:10.1093/nar/29.6.1352. PMC 29746 . PMID 11239002.

SLC12A9

Related Research Articles

References

Further reading