Laureates
| Citation Laureates | Nationality | Motivations | Institute | |
|---|---|---|---|---|
| 2008 [2] | ||||
| Shizuo Akira (born 1953) |  Japan | "for their research on toll-like receptors and innate immunity." | Osaka University | |
 2011 | Bruce Beutler (born 1957) |  United States | Scripps Research Institute | |
| 2011 | Jules A. Hoffmann (born 1941) |  France | French National Centre for Scientific Research | |
| Victor Ambros (born 1953) | United States | "for their discovery and analysis of the role of microRNAs (miRNAs) in gene regulation." | University of Massachusetts Chan Medical School | |
| Gary Ruvkun (born 1952) | United States | Harvard Medical School | ||
| Rory Collins (born 1955) |  United Kingdom | "for their contributions to clinical medicine and epidemiology through the development and application of meta-analysis." | University of Oxford | |
| Richard Peto (born 1943) | United Kingdom | |||
| 2009 [3] | ||||
| 2009 | Elizabeth Blackburn (born 1948) |  Australia United States | "for their roles in the discovery of and pioneering research on telomeres and telomerases." | University of California, San Francisco |
| 2009 | Carol W. Greider (born 1961) | United States | Johns Hopkins School of Medicine | |
| 2009 | Jack W. Szostak (born 1952) |  Canada United States | ||
| 2013 | James Rothman (born 1950) | United States | "for their research on cellular membrane trafficking." | Yale University |
| 2013 | Randy Schekman (born 1948) | United States | ||
| Seiji Ogawa (born 1934) | Japan | "for his fundamental discoveries leading to functional magnetic resonance imaging (fMRI), which has revolutionized basic research in brain science and diagnosis in clinical medicine." | Ogawa Laboratories for Brain Function Research | |
| 2010 [4] | ||||
| Douglas L. Coleman (1931–2014) | United States | "for the discovery of leptin, a hormone regulating appetite and metabolism." | Jackson Laboratory | |
| Jeffrey M. Friedman (born 1954) | United States | |||
| Ernest McCulloch (1926–2011) | Canada | "for the discovery of stem cells and the development of induced pluripotent stem cells." | Ontario Cancer Institute | |
| James E. Till (born 1931) | Canada | |||
| 2012 | Shinya Yamanaka (born 1962) | Japan | ||
| 2011 | Ralph M. Steinman (1943–2011) | Canada | "for the discovery of dendritic cells, key regulators of immune response." | Rockefeller University |
| 2011 [5] | ||||
| Brian Druker (born 1955) | United States | "for their development of imatinib and dasatinib, revolutionary, targeted treatments for chronic myeloid leukemia." | ||
| Charles Sawyers (born 1959) | United States | |||
| Nicholas Lydon (born 1957) | United Kingdom |
| ||
| Robert S. Langer (born 1948) | United States | "for their pioneering research in tissue engineering and regenerative medicine." | Massachusetts Institute of Technology | |
| Joseph P. Vacanti (born 1948) | United States | |||
| Jacques Miller (born 1931) | France Australia | "for his discovery of the function of the thymus and the identification of T cells and B cells in mammalian species." | ||
| Robert L. Coffman (born 1948) | United States | "for their discovery of two types of T lymphocytes, TH1 and TH2, and their role in regulating host immune response." | Dynavax Technologies | |
| Timothy Mosmann (born 1949) | United States | University of Rochester | ||
| 2012 [6] | ||||
| Charles David Allis (1951–2023) | United States | "for fundamental discoveries concerning histone modifications and their role in genetic regulation." | Rockefeller University | |
| Michael Grunstein (born 1946) | United States | University of California, Los Angeles | ||
| Anthony R. Hunter (born 1943) | United Kingdom United States | "for the discovery of tyrosine phosphorylation and contributions to understanding protein kinases and their role in signal transduction." | ||
| Tony Pawson (1952–2013) | Canada | "for identification of the phosphotyrosine binding SH2 domain and demonstrating its function in protein-protein interactions." | University of Toronto | |
| Richard Hynes (born 1944) | United Kingdom | "for pioneering discoveries of cell adhesion molecules, Hynes and Ruoslahti for integrins and Takeichi for cadherins." | ||
| Erkki Ruoslahti (born 1940) |  Finland | University of California, Santa Barbara | ||
| Masatoshi Takeichi (born 1943) | Japan | Riken Institute of Physical and Chemical Research | ||
| 2013 [7] | ||||
| Adrian Bird (born 1947) | United Kingdom | "for their fundamental discoveries concerning DNA methylation and gene expression." | University of Edinburgh | |
| Howard Cedar (born 1943) |  Israel United States | Hebrew University of Jerusalem | ||
| Aharon Razin (1935–2019) | Israel | |||
| Daniel J. Klionsky (born 1958) | United States | "for elucidating the molecular mechanisms and physiological function of autophagy." | University of Michigan | |
| Noboru Mizushima (born 1966) | Japan | University of Tokyo | ||
| 2016 | Yoshinori Ohsumi (born 1945) | Japan | Tokyo Institute of Technology | |
| Dennis Slamon (born 1948) | United States | "for his pioneering research identifying the HER-2/neu oncogene, leading to more effective cancer therapy." | University of California, Los Angeles | |
| 2014 [8] | ||||
| James E. Darnell] (born 1930) | United States | "for fundamental discoveries concerning eukaryotic transcription and gene regulation." | Rockefeller University | |
| Robert G. Roeder (born 1942) | United States | |||
| Robert Tjian (born 1949) |  Hong Kong United States | |||
| 2021 | David Julius (born 1955) | United States | "for elucidating molecular mechanisms of pain sensation." | University of California, San Francisco |
| Charles Lee (born 1969) |  South Korea | "for their discovery of large-scale copy number variation and its association with specific diseases." | Jackson Laboratory | |
| Stephen W. Scherer (born 1964) | Canada | University of Toronto | ||
| Michael Wigler (born 1947) | United States | Cold Spring Harbor Laboratory | ||
| 2015 [9] | ||||
| Jeffrey I. Gordon (born 1947) | United States | "for demonstrating the relationship between the human gut microbiome and physiology, metabolism, and nutrition." | Washington University in St. Louis | |
| Kazutoshi Mori (born 1958) | Japan | "for independently identifying the mechanism by which unfolded proteins in the endoplasmic reticulum are detected and corrected." | Kyoto University | |
| Peter Walter (born 1954) |  Germany United States | |||
| Alexander Rudensky (born 1956) | United States | "for their seminal discoveries concerning the nature and function of regulatory T cells and the transcription factor Foxp3." | ||
| Shimon Sakaguchi (born 1951) | Japan | Osaka University | ||
| Ethan M. Shevach (born 1943) | United States | National Institute of Allergy and Infectious Diseases | ||
| 2016 [10] | ||||
| 2018 | James P. Allison (born 1948) | United States | "for explaining how CD28 and CTLA-4 are regulators of T cell activation, modulating immune response." | University of Texas |
| Jeffrey Bluestone (born 1954) | United States | University of California, San Francisco | ||
| Craig B. Thompson (born 1953) | United States | Memorial Sloan Kettering Cancer Center | ||
| Gordon J. Freeman (born ?) | United States | "for elucidating programmed cell death-1 (PD-1) and its pathway, which has advanced cancer immunotherapy." | Harvard Medical School | |
| 2018 | Tasuku Honjo (born 1942) | Japan | Kyoto University | |
| Arlene Sharpe (born 1953) | United States | |||
| Michael N. Hall (born 1953) | United States Switzerland | "for discoveries of the growth regulator Target of Rapamycin (TOR) and the mechanistic Target of Rapamycin (mTOR)." | University of Basel | |
| David M. Sabatini (born 1968) | United States | |||
| Stuart Schreiber (born 1956) | United States | |||
| 2017 [11] | ||||
| Lewis C. Cantley (born 1949) | United States | "for discovery of the signaling pathway phosphoinositide 3-kinase (PI3K) and elucidation of its role in tumor growth." | Weill Cornell Medical College | |
| Karl J. Friston (born 1959) | United Kingdom | "for fundamental contributions to the analysis of brain imaging data, specifically through statistical parametric mapping and voxel-based morphometry." | University College London | |
| Yuan Chang-Moore (born 1959) |  Taiwan United States | "for their discovery of the Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8 (KSHV/HHV8)." | University of Pittsburgh Cancer Institute | |
| Patrick S. Moore (born 1956) | United States | |||
| 2018 [12] | ||||
| Minoru Kanehisa (born 1948) | Japan | "for contributions to bioinformatics, specifically for his development of the Kyoto Encyclopedia of Genes andGenomes (KEGG)." | Kyoto University | |
| Solomon H. Snyder (born 1938) | United States | "for his identification of receptors for many neurotransmitters and psychotropic agents." | Johns Hopkins University | |
| Napoleone Ferrara (born 1956) |  Italy United States | "for the discovery of vascular endothelial growth factor (VEGF), a key regulator of angiogenesis." | University of California, San Diego | |
| 2019 [13] | ||||
| Hans Clevers (born 1957) |  Netherlands | "for research on the Wnt signaling pathway and its role in stem cells and cancer." | Hubrecht Institute for Developmental Biology and Stem Cell Research | |
| John Kappler (born 1943) | United States | "for their discovery of T-cell tolerance by clonal elimination in the thymus." | National Jewish Health | |
| Philippa Marrack-Kappler (born 1945) | United Kingdom | |||
| Ernst Bamberg (born 1940) | Germany | "for contributions to the invention and development of optogenetics." | Max Planck Institute of Biophysics | |
| Karl Deisseroth (born 1971) | United States | |||
| Gero Miesenböck (born 1965) |  Austria | Oxford University | ||
| 2020 [14] | ||||
| Pamela J. Bjorkman (born 1956) | United States | "for determining the structure and function of major histocompatibility complex (MHC) proteins, a landmark discovery in molecular immunology that has contributed to drug and vaccine development." | California Institute of Technology | |
| Jack L. Strominger (born 1925) | United States | Harvard University | ||
| Yusuke Nakamura (born 1952) | Japan | "for pioneering research developing and applying genetic polymorphic markers and for contributions to genome-wide association studies, both heralding personalized approaches to cancer treatment." | ||
| Huda Zoghbi (born 1954) |  Lebanon United States | "for discoveries on the pathogenesis of neurological disorders including the genetic origins of Rett syndrome." | ||
| 2021 [15] | ||||
| Jean-Pierre Changeux (born 1936) | France | "for contributions to our understanding of neuroreceptors and especially the identification of the nicotinic acetylcholine receptor and its allosteric properties." | ||
| Toshio Hirano (born 1947) | Japan | "for discovery of interleukin-6, description of its physiological and pathological actions, that has contributed to drug development." | ||
| Tadamitsu Kishimoto (born 1939) | Japan | Osaka University | ||
| Karl Johnson (born 1929) | United States | "for identification and isolation of the Hantaan virus (hantavirus), agent of hemorrhagic fever with renal syndrome." | University of New Mexico | |
| Ho Wang Lee (1928–2022) | South Korea | Korea University|National Academy of Sciences | ||
| 2022 [16] | ||||
| Masato Hasegawa (born 1961) | Japan | "for the identification of TDP-43, a pathological signature of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), and for other contributions to the study of neurodegenerative diseases." | Tokyo Metropolitan Institute of Medical Science | |
| Virginia Man-Yee Lee (born 1945) |  China United States | University of Pennsylvania | ||
| Mary-Claire King (born 1946) | United States | "for demonstrating inherited susceptibility for breast and ovarian cancer and discovering the role played by mutations of the BRCA1 gene." | University of Washington | |
| Stuart Orkin (born 1946) | United States | "for foundational research on the genetic basis of blood diseases and for advancing gene therapy for sickle cell anemia and beta-thalassemia." | ||
| 2023 [17] | ||||
| Carl H. June (born 1953) | United States | "for breakthrough research advancing chimeric antigen receptor T-cell therapy for the treatment of cancer." | University of Pennsylvania | |
| Steven A. Rosenberg (born 1940) | United States | National Cancer Institute | ||
| Michel Sadelain (born 1960) | United States | Memorial Sloan Kettering Cancer Center | ||
| Rob Knight (born 1976) | United States | "for computational and experimental research revealing the complex microbial ecosystems of the human body." | University of California San Diego | |
| Emmanuel Mignot (born 1959) | United States | "for genetic and physiological studies of the sleep/wake cycle and the discovery of hypocretin/orexin as important regulators of sleep involved in the cause of narcolepsy." | Stanford University | |
| Clifford B. Saper (born 1965) | United States | Harvard Medical School | ||
| Masashi Yanagisawa (born 1960) | Japan United States | University of Tsukuba | ||
