Mitochondrial 2-oxoglutarate/malate carrier protein

Last updated

SLC25A11
Identifiers
Aliases SLC25A11 , OGC, SLC20A4, solute carrier family 25 member 11, PGL6
External IDs OMIM: 604165; MGI: 1915113; HomoloGene: 2637; GeneCards: SLC25A11; OMA:SLC25A11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003562
NM_001165417
NM_001165418

NM_024211

RefSeq (protein)

NP_001158889
NP_001158890
NP_003553

NP_077173

Location (UCSC) Chr 17: 4.94 – 4.94 Mb Chr 11: 70.54 – 70.54 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene. [5] [6] [7] Inactivating mutations in this gene predispose to metastasic paraganglioma. [8]

Contents

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000108528 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000014606 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenetics and Cell Genetics. 83 (3–4): 256–257. doi:10.1159/000015198. PMID   10072597. S2CID   36221506.
  6. Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Sequence. 3 (2): 79–88. doi:10.3109/10425179209034000. PMID   1457818.
  7. "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".
  8. Buffet A, Morin A, Castro-Vega LJ, Habarou F, Lussey-Lepoutre C, Letouzé E, et al. (April 2018). "Germline Mutations in the Mitochondrial 2-Oxoglutarate/Malate Carrier SLC25A11 Gene Confer a Predisposition to Metastatic Paragangliomas". Cancer Research. 78 (8): 1914–1922. doi: 10.1158/0008-5472.CAN-17-2463 . PMID   29431636.

Further reading