Solute carrier organic anion transporter family member 4A1

SLCO4A1
Identifiers
Aliases	SLCO4A1 , OATP-E, OATP1, OATP4A1, OATPE, OATPRP1, POAT, SLC21A12, solute carrier organic anion transporter family member 4A1
External IDs	OMIM: 612436 MGI: 1351866 HomoloGene: 9482 GeneCards: SLCO4A1
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20q13.33 Start 62,642,503 bp [1] End 62,685,785 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 H4 Start 180,098,038 bp [2] End 180,116,660 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lung upper lobe of left lung skin of abdomen left uterine tube tibial nerve gastric mucosa gastrocnemius muscle subcutaneous adipose tissue left ventricle body of stomach Top expressed in Paneth cell retinal pigment epithelium trigeminal ganglion conjunctival fornix epithelium of stomach secondary oocyte ciliary body hair follicle facial motor nucleus seminal vesicula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transporter activity sodium-independent organic anion transmembrane transporter activity thyroid hormone transmembrane transporter activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process ion transport sodium-independent organic anion transport thyroid hormone transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 28231 108115 Ensembl ENSG00000101187 ENSMUSG00000038963 UniProt Q96BD0 Q8K078 RefSeq (mRNA) NM_016354 NM_148933 NM_001355218 RefSeq (protein) NP_057438 NP_683735 NP_001342147 Location (UCSC) Chr 20: 62.64 – 62.69 Mb Chr 2: 180.1 – 180.12 Mb PubMed search [3] [4]
Wikidata
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Solute carrier organic anion transporter family member 4A1 is a protein that in humans is encoded by the SLCO4A1 gene. ^{[5] [6]}

See also

• Solute carrier family

References

1. GRCh38: Ensembl release 89: ENSG00000101187 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038963 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A (Jul 2000). "Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family". Biochem Biophys Res Commun. 273 (1): 251–60. doi:10.1006/bbrc.2000.2922. PMID   10873595.
6. "Entrez Gene: SLCO4A1 solute carrier organic anion transporter family, member 4A1".

Further reading

• Fujiwara K, Adachi H, Nishio T, et al. (2001). "Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner". Endocrinology. 142 (5): 2005–12. doi: 10.1210/endo.142.5.8115 . PMID   11316767.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Pizzagalli F, Varga Z, Huber RD, et al. (2003). "Identification of steroid sulfate transport processes in the human mammary gland" (PDF). J. Clin. Endocrinol. Metab. 88 (8): 3902–12. doi: 10.1210/jc.2003-030174 . PMID   12915686.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wang P, Wang JJ, Xiao Y, et al. (2005). "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface". J. Biol. Chem. 280 (34): 30143–9. doi: 10.1074/jbc.M503969200 . PMID   15994332.