Zinc transporter 7

SLC30A7
Identifiers
Aliases	SLC30A7 , ZNT7, ZnT-7, ZnTL2, solute carrier family 30 member 7
External IDs	OMIM: 611149; MGI: 1913750; HomoloGene: 11332; GeneCards: SLC30A7; OMA:SLC30A7 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p21.2 Start 100,896,076 bp [1] End 100,981,757 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 G1 Start 115,732,622 bp [2] End 115,801,055 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell buccal mucosa cell cartilage tissue mucosa of paranasal sinus tibia visceral pleura nasal epithelium mucosa of ileum jejunal mucosa thymus Top expressed in lacrimal gland seminal vesicula ectoderm otic vesicle saccule Paneth cell otic placode medullary collecting duct salivary gland submandibular gland More reference expression data BioGPS n/a
Gene ontology Molecular function cation transmembrane transporter activity zinc ion transmembrane transporter activity Cellular component cytoplasm integral component of membrane perinuclear region of cytoplasm vesicle Golgi apparatus membrane cytoplasmic vesicle Biological process sequestering of zinc ion regulation of sequestering of zinc ion response to zinc ion cation transport zinc ion transport ion transport cation transmembrane transport zinc ion transmembrane transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 148867 66500 Ensembl ENSG00000162695 ENSMUSG00000054414 UniProt Q8NEW0 Q9JKN1 RefSeq (mRNA) NM_001144884 NM_133496 NM_023214 RefSeq (protein) NP_001138356 NP_598003 NP_075703 Location (UCSC) Chr 1: 100.9 – 100.98 Mb Chr 3: 115.73 – 115.8 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc transporter 7 is a protein that in humans is encoded by the SLC30A7 gene. ^{[5] [6]}

See also

• Solute carrier family

References

1. GRCh38: Ensembl release 89: ENSG00000162695 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000054414 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kirschke CP, Huang L (Feb 2003). "ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus". J Biol Chem. 278 (6): 4096–102. doi: 10.1074/jbc.M207644200 . PMID   12446736.
6. "Entrez Gene: SLC30A7 solute carrier family 30 (zinc transporter), member 7".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Devergnas S, Chimienti F, Naud N, et al. (2004). "Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study". Biochem. Pharmacol. 68 (4): 699–709. doi:10.1016/j.bcp.2004.05.024. PMID   15276077.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.