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| Formula | C10H10Br2N2 |
| Molar mass | 318.012 g·mol−1 |
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5,6-Dibromotryptamine is a substituted tryptamine and indolic alkaloid found in some marine sponges such as Hyrtios sp. found in the South Pacific area. 5,6-dibromotryptamine is potentially an anti bacterial and anti cancer agent. [1] [2]
Sponges, the members of the phylum Porifera, are a basal animal clade as a sister of the Diploblasts. They are multicellular organisms that have bodies full of pores and channels allowing water to circulate through them, consisting of jelly-like mesohyl sandwiched between two thin layers of cells.
Okadaic acid, C44H68O13, is a toxin produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish. One of the primary causes of diarrhetic shellfish poisoning, okadaic acid is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells. A polyketide, polyether derivative of a C38 fatty acid, okadaic acid and other members of its family have shined light upon many biological processes both with respect to dinoflagellete polyketide synthesis as well as the role of protein phosphatases in cell growth.
Fucoidan is a long chain sulfated polysaccharide found in various species of brown algae. Commercially available fucoidan is commonly extracted from the seaweed species Fucus vesiculosus, Cladosiphon okamuranus, Laminaria japonica and Undaria pinnatifida. Variant forms of fucoidan have also been found in animal species, including the sea cucumber.
A depsipeptide is a peptide in which one or more of its amide, -C(O)NHR-, groups are replaced by the corresponding ester, -C(O)OR, Many depsipeptides have both peptide and ester linkages. They are mainly found in marine and microbial natural products.
5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a psychedelic brominated indole alkaloid found in the sponges Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida alongside 5,6-Dibromo-DMT and seven other alkaloids. It is the 5-bromo derivative of DMT, a psychedelic found in many plants and animals.
Desformylflustrabromine (dFBr) is a monomethyltryptamine derivative which was first isolated as a secondary metabolite of the marine bryozoan Flustra foliacea.
MDPI, acronym of Multidisciplinary Digital Publishing Institute, is a publisher of open access scientific journals. Founded by Shu-Kun Lin as a chemical sample archive, it publishes over 380 diverse, peer-reviewed, open access journals and is continuously expanding its portfolio. MDPI is the largest open access publisher in the world and the fifth largest publisher overall in terms of journal paper output. The number of published papers has been growing significantly in the last decade with year over year growth of over 50% in 2017, 2018 and 2019.
Palau'amine is a toxic alkaloid compound synthesized naturally by Stylotella agminata, a species of sea sponge found in the southwest Pacific Ocean. The name of the molecule derives from the island nation of Palau, near which the sponges are found.
Tenacibaculum mesophilum is a bacterium. It was first isolated from sponge and green algae which were collected on the coast of Japan and Palau. Its type strain is MBIC 1140T.
Daphnoretin is a protein kinase C activator isolated from Wikstroemia indica C.A. Mey, one of the 50 fundamental herbs in traditional Chinese medicine. It has also been found to occur in Stellera chamaejasme - the single species in a genus closely related to Wikstroemia within the family Thymelaceae.
Nicotinamide riboside (NR, SR647) is a pyridine-nucleoside similar to vitamin B3, functioning as a precursor to nicotinamide adenine dinucleotide or NAD+.
Poribacteria are a candidate phylum of bacteria originally discovered in the microbiome of marine sponges (Porifera). Poribacteria are Gram-negative primarily aerobic mixotrophs with the ability for oxidative phosphorylation, glycolysis, and autotrophic carbon fixation via the Wood – Ljungdahl pathway. Poribacterial heterotrophy is characterised by an enriched set of glycoside hydrolases, uronic acid degradation, as well as several specific sulfatases. This heterotrophic repertoire of poribacteria was suggested to be involved in the degradation of the extracellular sponge host matrix.
Dysidea arenaria is a species of marine sponge (poriferan) found in the Pacific Ocean. It is a member of the order Dictyoceratida, one of two sponge orders that make up the keratose or "horny" sponges in which a mineral skeleton is absent and a skeleton of organic fibers is present instead.
Geodia barretti is a massive deep-sea sponge species found in the boreal waters of the North Atlantic Ocean, and is fairly common on the coasts of Norway and Sweden. It is a dominant species in boreal sponge grounds. Supported by morphology and molecular data, this species is classified in the family Geodiidae.
Mycale hentscheli is a marine sponge, which is known to be a rich source of bioactive small molecules. These natural products originate from the sponge's microbiota. Examples of these molecules include the potent cytotoxic polyketides: pateamine, peloruside, and mycalamide.
Latrunculia biformis, the mud-clump sponge, is a widespread deep sea demosponge from the southern hemisphere.
Pseudoceratina is a genus of sponge within the family Pseudoceratinidae. They are characterized by possession of a dendritic fiber skeleton lacking laminar bark but containing pith. They have been found in a variety of habitats including the Great Barrier reef, the Red Sea, and Jamaica. Sponges of this genus have a microbiome known to produce a variety of chemicals that are used in pharmaceutical and anti-fouling activities. Notably, a species in this genus produces a chemical that is effective in inhibiting the migration of metastatic breast cancer cells.
6-Bromotryptamine is a substituted tryptamine that is a marine natural product.
5,6-Dibromo-N-methyltryptamine (5,6-Dibromo-NMT) is a substituted tryptamine alkaloid that occurs naturally in marine sponges.
5,6-Dibromo-DMT is a substituted tryptamine alkaloid found in some marine sponges. It is briefly mentioned in Alexander Shulgin's book TiHKAL under the DMT entry and is stated to be found, along with other typtamines, in Smenospongia aurea and other sponges.
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