Choline transporter-like protein 2

SLC44A2
Identifiers
Aliases	SLC44A2 , CTL2, PP1292, solute carrier family 44 member 2
External IDs	OMIM: 606106 MGI: 1915932 HomoloGene: 10711 GeneCards: SLC44A2
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.2 Start 10,602,457 bp [1] End 10,644,557 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A3 Start 21,231,994 bp [2] End 21,266,324 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve right lung spleen right coronary artery popliteal artery upper lobe of left lung left coronary artery stromal cell of endometrium right lobe of thyroid gland body of stomach Top expressed in aortic valve ascending aorta left lung lobe right lung lobe stria vascularis hair follicle internal carotid artery external carotid artery medullary collecting duct condyle More reference expression data BioGPS n/a
Gene ontology Molecular function choline transmembrane transporter activity signal transducer activity Cellular component integral component of membrane lysosomal membrane plasma membrane extracellular exosome membrane specific granule membrane Biological process positive regulation of I-kappaB kinase/NF-kappaB signaling phosphatidylcholine biosynthetic process choline transport transmembrane transport signal transduction neutrophil degranulation transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57153 68682 Ensembl ENSG00000129353 ENSMUSG00000057193 UniProt Q8IWA5 Q8BY89 RefSeq (mRNA) NM_001145056 NM_020428 NM_001363611 NM_001199186 NM_152808 NM_001359227 RefSeq (protein) NP_001138528 NP_065161 NP_001350540 NP_001186115 NP_690021 NP_001346156 Location (UCSC) Chr 19: 10.6 – 10.64 Mb Chr 9: 21.23 – 21.27 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Choline transporter-like protein 2 is a protein that in humans is encoded by the SLC44A2 gene. ^{[5] [6] [7]}

See also

• Solute carrier family

References

1. GRCh38: Ensembl release 89: ENSG00000129353 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000057193 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (Mar 2000). "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins". Proc Natl Acad Sci U S A. 97 (4): 1835–40. Bibcode:2000PNAS...97.1835O. doi: 10.1073/pnas.030339697 . PMC   26522 . PMID   10677542.
6. Traiffort E, Ruat M, O'Regan S, Meunier FM (Feb 2005). "Molecular characterization of the family of choline transporter-like proteins and their splice variants". J Neurochem. 92 (5): 1116–25. doi: 10.1111/j.1471-4159.2004.02962.x . PMID   15715662. S2CID   30921826.
7. "Entrez Gene: SLC44A2 solute carrier family 44, member 2".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi: 10.1038/sj.onc.1206406 . PMID   12761501.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Nair TS, Kozma KE, Hoefling NL, et al. (2004). "Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss". J. Neurosci. 24 (7): 1772–9. doi: 10.1523/JNEUROSCI.5063-03.2004 . PMC   6730453 . PMID   14973250.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID   16303743.