| State | Airport | Airline |
|---|
| Alaska | Anchorage (ANC) | Alaska Airlines |
| Atlas Air |
| FedEx Express |
| Polar Air Cargo |
| Ravn Alaska |
| UPS Airlines |
| Arizona | Phoenix-Sky Harbor (PHX) | American Airlines |
| Frontier Airlines (focus city) |
| Southwest Airlines (focus city) |
| Phoenix-Mesa (AZA) | Allegiant Air (focus city) |
| California | Hollywood Burbank Airport (BUR) | Avelo Airlines (focus city) |
| Los Angeles (LAX) | Allegiant Air (focus city) |
| Alaska Airlines |
| American Airlines [8] |
| Delta Air Lines [9] |
| JetBlue Airways (focus city) |
| Southwest Airlines (focus city) |
| United Airlines [10] |
| Oakland (OAK) | Southwest Airlines (focus city) |
| San Diego (SAN) | Alaska Airlines |
| San Francisco (SFO) | Alaska Airlines |
| United Airlines |
| San Jose (SJC) | Alaska Airlines (focus city) |
| Santa Rosa (STS) | Avelo Airlines (focus city) |
| Colorado | Denver (DEN) | Frontier Airlines |
| Southwest Airlines (focus city) |
| United Airlines [10] |
| Connecticut | Hartford (BDL) | Breeze Airways (focus city) |
| Avelo Airlines (focus city) |
| New Haven (HVN) | Avelo Airlines (focus city) |
| Delaware | Wilmington Airport (DE) (ILG) | Avelo Airlines (focus city) |
| Florida | Miami (MIA) | American Airlines [8] |
| Frontier Airlines (focus city) |
| Spirit Airlines (focus city) |
| Eastern Airlines, LLC |
| Fort Lauderdale (FLL) | JetBlue Airways (focus city) |
| Silver Airways |
| Spirit Airlines (focus city) |
| Allegiant Air (focus city) |
| Orlando (MCO) | Southwest Airlines (focus city) |
| Frontier Airlines (focus city) |
| Spirit Airlines (focus city) |
| JetBlue Airways (focus city) |
| Avelo Airlines (focus city) |
| Tampa (TPA) | Silver Airways |
| Frontier Airlines (focus city) |
| Breeze Airways (focus city) |
| Orlando-Sanford (SFB) | Allegiant Air (focus city) |
| Destin-Fort Walton Beach (VPS) | Allegiant Air (focus city) |
| Punta Gorda (PGD) | Allegiant Air (focus city) |
| St. Petersburg (FL) (PIE) | Allegiant Air (focus city) |
| Lakeland | Avelo Airlines (focus city) |
| Sarasota (SRQ) | Allegiant Air (focus city) |
| Georgia | Atlanta (ATL) | Delta Air Lines [11] |
| Frontier Airlines (focus city) |
| Southwest Airlines (focus city) |
| Spirit Airlines (focus city) |
| Savannah (SAV) | Allegiant Air (focus city) |
| Hawaii | Honolulu (HNL) | Hawaiian Airlines |
| Kahului (OGG) | Hawaiian Airlines [12] |
| Idaho | Boise (BOI) | Alaska Airlines (focus city) |
| Illinois | Chicago-Midway (MDW) | Southwest Airlines (focus city) |
| Frontier Airlines (focus city) |
| Chicago-O'Hare (ORD) | American Airlines [8] |
| Spirit Airlines (focus city) |
| United Airlines [10] |
| Indiana | Indianapolis (IND) | Allegiant Air (focus city) |
| FedEx Express |
| Mountain Air Cargo |
| Republic Airways (base) |
| Iowa | Des Moines (DSM) | Allegiant Air (focus city) |
| Kentucky | Cincinnati (CVG) | Allegiant Air (focus city) |
| Amazon Air |
| DHL Aviation |
| Louisville (SDF) | United Parcel Service (UPS) |
| Louisiana | New Orleans (MSY) | Breeze Airways (focus city) |
| Maryland | Baltimore (BWI) | Southwest Airlines (focus city) |
| Massachusetts | Boston (BOS) | Delta Air Lines [13] |
| JetBlue Airways (focus city) |
| Cape Air |
| Michigan | Detroit (DTW) | Delta Air Lines [11] |
| Spirit Airlines (focus city) |
| Flint (FNT) | Allegiant Air (focus city) |
| Grand Rapids (GRR) | Allegiant Air (focus city) |
| Minnesota | Minneapolis (MSP) | Delta Air Lines [11] |
| Sun Country Airlines |
| Nevada | Las Vegas (LAS) | Allegiant Air (focus city) |
| Frontier Airlines (focus city) |
| JSX (focus city) |
| Southwest Airlines (focus city) |
| Spirit Airlines (focus city) |
| Sun Country Airlines (focus city) |
| New Jersey | Atlantic City (ACY) | Spirit Airlines (focus city) |
| Newark (EWR) | United Airlines [14] |
| Trenton (TTN) | Frontier Airlines (focus city) |
| New York | New York-JFK (JFK) | American Airlines [8] |
| Delta Air Lines [11] |
| JetBlue Airways (focus city) |
| Eastern Airlines, LLC (focus city) |
| New York-LaGuardia (LGA) | American Airlines |
| Delta Air Lines |
| North Carolina | Raleigh (RDU) | Delta Air Lines (focus city) |
| Avelo Airlines (focus city) |
| Charlotte (CLT) | American Airlines |
| Greensboro (GSO) | FedEx Express |
| Asheville (AVL) | Allegiant Air (focus city) |
| Ohio | Cleveland (CLE) | Frontier Airlines (focus city) |
| Oregon | Portland (PDX) | Alaska Airlines |
| Pennsylvania | Philadelphia (PHL) | American Airlines |
| Frontier Airlines (focus city) |
| Pittsburgh (PIT) | Southern Airways Express |
| Allegiant Air (focus city) |
| Allentown (ABE) | Allegiant Air (focus city) |
| South Carolina | Charleston (CHS) | Breeze Airways (focus city) |
| Columbia (CAE) | United Parcel Service (UPS) |
| Tennessee | Memphis (MEM) | FedEx Express |
| Southern Airways Express |
| Knoxville (TYS) | Allegiant Air (focus city) |
| Nashville (BNA) | Southwest Airlines (focus city) |
| Allegiant Air (focus city) |
| Texas | Dallas/Fort Worth (DFW) | American Airlines [8] |
| Spirit Airlines (focus city) |
| Sun Country Airlines (focus city) |
| Dallas-Love Field (DAL) | Southwest Airlines (focus city) |
| Houston-Intercontinental (IAH) | United Airlines [14] |
| Houston-Hobby (HOU) | Southwest Airlines (focus city) |
| Austin (AUS) | Allegiant Air (focus city) |
| Utah | Salt Lake City (SLC) | Delta Air Lines [11] |
| Provo (PVU) | Allegiant Air (focus city) [15] |
| Virginia | Norfolk (ORF) | Breeze Airways (focus city) |
| Washington-Dulles (IAD) | United Airlines [10] |
| Washington-Reagan (DCA) | American Airlines |
| Washington | Seattle (SEA) | Alaska Airlines |
| Delta Air Lines [11] |
| Bellingham (BLI) | Allegiant Air (focus city) |
| Wisconsin | Appleton (ATW) | Allegiant Air (focus city) |