UDP-xylose and UDP-N-acetylglucosamine transporter

SLC35B4
Identifiers
Aliases	SLC35B4 , YEA, YEA4, solute carrier family 35 member B4
External IDs	OMIM: 610923 MGI: 1931249 HomoloGene: 5799 GeneCards: SLC35B4
Gene location (Human)
Chr.	Chromosome 7 (human)
End	134,316,930 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	34,154,046 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; placenta; ; retinal pigment epithelium; ; tibia; ; superior frontal gyrus; ; postcentral gyrus; ; pancreatic epithelial cell;
	Top expressed in
	saccule; ; otic placode; ; proximal tubule; ; yolk sac; ; kidney; ; secondary oocyte; ; superior frontal gyrus; ; thymus; ; cerebellar cortex; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; UDP-xylose transmembrane transporter activity ; GDP-fucose transmembrane transporter activity ; UDP-N-acetylglucosamine transmembrane transporter activity ; 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity ; transmembrane transporter activity ;
Cellular component	integral component of membrane ; endoplasmic reticulum ; membrane ; integral component of Golgi membrane ; integral component of endoplasmic reticulum membrane ; Golgi apparatus ; Golgi membrane ;
Biological process	UDP-xylose transmembrane transport ; regulation of gluconeogenesis ; carbohydrate transport ; transmembrane transport ; GDP-fucose transmembrane transport ; UDP-N-acetylglucosamine transmembrane transport ; 3'-phospho-5'-adenylyl sulfate transmembrane transport ;
	Sources:Amigo / QuickGO
Orthologs
	84912
	58246
	ENSG00000205060
	ENSMUSG00000018999
	Q969S0
	Q8CIA5
	NM_032826
	NM_021435
	NP_116215
	NP_067410
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 17, 2023

UDP-xylose and UDP-N-acetylglucosamine transporter is a protein that in humans is encoded by the SLC35B4 gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000205060 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018999 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

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Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961 . PMID 12690205.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ashikov A, Routier F, Fuhlrott J, et al. (2005). "The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine". J. Biol. Chem. 280 (29): 27230–5. doi: 10.1074/jbc.M504783200 . PMID 15911612.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B (2006). "Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family". Biochem. J. 400 (2): 281–9. doi:10.1042/BJ20060429. PMC 1652819 . PMID 16965264.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000205060 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000018999 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

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UDP-xylose and UDP-N-acetylglucosamine transporter

Contents

See also

Related Research Articles

References

Further reading